Biochemical and morphological changes in carp (Cyprinus carpio L.) liver following exposure to copper sulfate and tannic acid

Varanka, Zsolt; Rojik, I.; Varanka, István; Nemcsók, J.; Ábrahám, Magdolna

doi:10.1016/s1532-0456(01)00166-1

Cited by 93 publications

(70 citation statements)

References 30 publications

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“…Our findings are in agreement with those of Varanka et al (2001) who suggested out that metal accumulation in the liver of common carp (Cyprinus carpio L., 1758) causes hepatocyte lysis, cirrhosis and ultimately death.…”

Section: Histological Alterationssupporting

confidence: 93%

Biomarkers in European perch (Perca fluviatilis) liver from a metal-contaminated dam lake

et al. 2014

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The present study was carried out in three seasons -spring, summer and autumn in Topolnitsa Dam Lake (Bulgaria) which has been subjected to continuous contamination with trace metals due to copper extraction in the area. We investigated the trace metal levels in surface water and liver samples of European perch (Perca fluviatilis L.). We also linked the metal levels we determined with the various histological and biochemical changes which we observed. Lesions in the liver parenchyma were found to be degenerative and necrotic, as well as, they were presented as hyperemia which consequently leads to disturbances in the hepatic blood circulation. Activities of the hepatic enzymes lactate dehydrogenase (LDH), alanine aminotransferase (ALAT) and aspartate aminotransferase (ASAT) were found to be significantly elevated, particularly in summer. Therefore, based on our results we could recommend that the investigated tissue and cell alterations may be successfully applied as reliable biomarkers for monitoring polluted with a mixture of trace metals freshwater ecosystems.

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Section: Histological Alterationssupporting

confidence: 93%

Biomarkers in European perch (Perca fluviatilis) liver from a metal-contaminated dam lake

et al. 2014

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“…Several studies had shown a variety of changes in the liver of O. niloticus, resulting from exposure to different toxic chemicals (Visoottiviseth et al 1999, FigueiredoFernandes et al 2006a. Moreover, it was also reported by several studies that chronic copper accumulation in the liver of fish causes hepatocyte lysis, cirrhosis and ultimately death (Pourahamad & O'Brien 2000, Varanka et al 2001.…”

Section: Discus Discus Discus Discus Discussion Sion Sion Sion Sionmentioning

confidence: 87%

“…When exposed to toxic concentrations, organs of aquatic animals may accumulate copper (Pelgrom et al 1995, Grosell et al 1996, Mazon et al 2002, which can lead to redox reactions generating free radicals and, therefore, may cause biochemical and morphological alterations (Varanka et al 2001, Monteiro et al 2005. Gills are the first target of waterborne pollutants due to the constant contact with the external environment, as well as the main place for copper uptake (Campbell et al 1979, Perry & Laurent 1993.…”

Section: Introduction Introduction Introduction Introduction Introducmentioning

confidence: 99%

Histopathological changes in liver and gill epithelium of Nile tilapia, Oreochromis niloticus, exposed to waterborne copper

et al. 2007

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Nile tilapia, Oreochromis niloticus, of both sexes were reared in freshwater and exposed to 0.5, 1.0 and 2.5mg L-1 of waterborne copper for a period of 21 days. Liver and gill samples were collected after 21 days of exposure to copper and lesions were analyzed by light microscopy. The main histopathological changes observed in gills exposed to the highest concentration were edema, lifting of lamellar epithelia and an intense vasodilatation of the lamellar vascular axis. Although less frequent, lamellar fusion caused by the filamentar epithelium proliferation and some lamellar aneurisms were also found. The liver of control group exhibited a quite normal architecture, while the fish exposed to copper showed vacuolation and necrosis. These hepatic alterations were more evident in fish exposed to 1.0 and 2.5mg L-1 copper concentrations. The number of hepatocytes nucleus per mm² of hepatic tissue decreased with the increase of copper concentration. In contrast, the hepatic somatic index was high in fish exposed at 2.5mg L-1 of copper. In short, this work advance new knowledge as influence of copper in the gill and liver histology of O. niloticus and demonstrated that their effects could be observed at different concentrations.

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“…For these reasons, the determination of tannic acid has been of great importance. Several methods have been developed for this purpose including colorimetry, chromatography, chemiluminescence and spectrophotometry (Varanka et al 2001;Xie & Cui 2003;Naczk & Shahidi 2004;Pelozo et al 2008). Compared with those methods above, electrochemical techniques for tannic acid determination have some advantages such as: high sensitivity, accuracy, simplicity and low expense (Lu 2004;Xu et al 2009;Raj et al 2013;Vu et al 2013).…”

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confidence: 99%

Voltammetric determination of tannic acid in beverages using pencil graphite electrode

Vu¹,

Ertek²,

Dilgin³

et al. 2015

Czech J. Food Sci.

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Vu D.L., Ertek B., Dilgin Y., Červenka L. (2015): Voltammetric determination of tannic acid in beverages using pencil graphite electrode. Czech J. Food Sci., 33: 72-76.The pretreated pencil graphite electrode (Pre-PGE) prepared by a chronoamperometry technique was applied for the determination of tannic acid using anodic stripping differential pulse voltammetry. The currents obtained from voltammetry measurements at optimum conditions were linearly correlated with the concentration of tannic acid. Calibration curve was obtained for tannic acid in the concentration range of 5.0-500 × 10 -9 mol/l. The limit of detection was found to be 1.5 × 10 -9 mol/l. The content of tannic acid in beverage samples determined with Pre-PGE was in good agreement with that obtained by the standard spectrophotometric method.

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Biochemical and morphological changes in carp (Cyprinus carpio L.) liver following exposure to copper sulfate and tannic acid

Cited by 93 publications

References 30 publications

Biomarkers in European perch (Perca fluviatilis) liver from a metal-contaminated dam lake

Biomarkers in European perch (Perca fluviatilis) liver from a metal-contaminated dam lake

Histopathological changes in liver and gill epithelium of Nile tilapia, Oreochromis niloticus, exposed to waterborne copper

Voltammetric determination of tannic acid in beverages using pencil graphite electrode

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