Biochemical and histological effects of five weeks ingestion of Zamzam water on the liver and kidneys of Wistar rats

Doghaither, Huda A. Al; Al-Sohaibani, Razan M.; Omar, Ulfat M.; Alharbi, Hassan

doi:10.1016/j.jsps.2020.12.007

Cited by 3 publications

(1 citation statement)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The microscopic appearance of liver tissue from healthy rats (T-) presents a normal physiological appearance with well-structured and delineated centrilobular veins, biliary ducts, and portal spaces. Several studies that focused on the histological study of rat liver tissue presented the same aspect [83][84][85].…”

Section: Histological Studymentioning

confidence: 98%

Antioxidant Activity and Effectiveness of Fig Extract in Counteracting Carbon Tetrachloride-Induced Oxidative Damage in Rats

Kebal,

Djebli,

Pokajewicz

et al. 2024

Molecules

View full text Add to dashboard Cite

Figs are the edible fruits of the fig tree, Ficus carica L., that have been used for centuries for human consumption and in traditional medicine, to treat skin problems, inflammation, and gastrointestinal disorders. Our previous study investigated the presence of phenolic compounds in aqueous extracts of two Algerian popular fig varieties, azendjar (Az) and taamriouth (Ta), as well as their in vitro antioxidant activity. In this study, we assessed hydroethanolic extracts of these fig varieties. The total phenolic content was measured, along with the phenolic profile. Rutin was determined to be the dominant phenolic compound, followed by vanillic acid, 3,4-dihydroxybenzoic acid, quercetin, 4-hydroxybenzoic acid, rosmarinic acid (in Az only), and cinnamic acid. The antioxidant activity of the extracts was evaluated both in vitro (DPPH and FRAP assays) and in vivo, in rats intoxicated with carbon tetrachloride. In all assays, the fig extract—especially the dark-peeled fig variety azendjar—showed antioxidant potency. The administration of fig extract resulted in a reduction in liver damage, expressed by both different biochemical markers and histopathological study (less degraded liver architecture, reduced fibrosis, and only mild inflammation). A dose-dependent therapeutic effect was observed. The extract from the dark-peeled fig variety, Az, was characterized by a higher phenolic content and a stronger antioxidant activity than the extract from the light-peeled variety—Ta. Our study justifies the use of figs in traditional healing and shows the potential of using fig extracts in natural medicines and functional foods.

show abstract

Section: Histological Studymentioning

confidence: 98%

Antioxidant Activity and Effectiveness of Fig Extract in Counteracting Carbon Tetrachloride-Induced Oxidative Damage in Rats

Kebal,

Djebli,

Pokajewicz

et al. 2024

Molecules

View full text Add to dashboard Cite

show abstract

Metallic profile of Zamzam water: Determination of minerals, metals and metalloids by ICP-MS

Zergui¹,

Aledeh²,

Hamad³

2022

Journal of Trace Elements and Minerals

View full text Add to dashboard Cite

Health Issues of Nigerian Muslim Pilgrims in The Immediate Post-Covid-19 Era Hajj Year 2022– Part II (Non-Communicable Diseases)

Saheed,

Isiaka,

Mande

et al. 2023

IIMJ

View full text Add to dashboard Cite

Background: Hajj is an important rite in the life of devout Muslims, requiring the devolvement of physical and material resources in its execution. Limitations posed by COVID-19 on the performance of Hajj make the year 2022 hajj to be an atypical one compared to other years' international hajj. Nigerian pilgrims are peculiar as a low-and middle-income country (LAMIC) with the highest number of Muslim pilgrims from Africa. The objective of this article is to review the health implications of Hajj and peculiarities of the post- COVID 19 era, regarding non-communicable diseases in Nigerian pilgrims based on literature, the interaction of authors with pilgrims, and the experiences of an author as a pilgrim. Results: Commonly encountered non-communicable respiratory, cardiovascular, nutritional, gastrointestinal, endocrine, reproductive, neurological, and musculoskeletal health issues in Nigerian pilgrims were explored. Preventive health strategies by individual pilgrims, the national medical team of National Hajj Commission of Nigeria (NAHCON), the Ministry of Health (MOH) of the Kingdom of Saudi Arabia (KSA) and other stakeholders involved directly or indirectly in conducting Hajj rites were appraised. This includes but not limited to illness screening, chronic illness management, life style modification, medication adherence, and accident prevention. Conclusions: It was concluded that the efforts of the Kingdom of Saudi Arabia, as well as Nigeria authorities on Hajj health services, are commendable, though there are still a lot of areas that need to be improved upon. Significant importance should be given to pre-hajj and post-hajj screening of pilgrims for communicable health issues in pilgrims to enable optimal execution of hajj task and maintenance of pilgrims’ health beyond hajj period.

show abstract

Biochemical and histological effects of five weeks ingestion of Zamzam water on the liver and kidneys of Wistar rats

Cited by 3 publications

References 20 publications

Antioxidant Activity and Effectiveness of Fig Extract in Counteracting Carbon Tetrachloride-Induced Oxidative Damage in Rats

Antioxidant Activity and Effectiveness of Fig Extract in Counteracting Carbon Tetrachloride-Induced Oxidative Damage in Rats

Metallic profile of Zamzam water: Determination of minerals, metals and metalloids by ICP-MS

Health Issues of Nigerian Muslim Pilgrims in The Immediate Post-Covid-19 Era Hajj Year 2022– Part II (Non-Communicable Diseases)

Contact Info

Product

Resources

About