Biochemical alterations in patients with acute leukaemia

Abstract

After statistical analysis of biochemical parameters in 60 patients with acute leukaemia, it was concluded that most prominent alterations were elevated values of serum lactate-dehydrogenase, uric acid and calcaemia. In patients with acute myeloid leukaemia, prothrombin time and partial thromboplastin time were significantly prolonged, and in patients with acute lymphocytic leukaemia serum immunoglobuline levels were significantly lower. Biochemical alterations may produce some implications for the general state of the patient, as well as for the clinical course of the disease, its complications and outcome, with possible influence on the effect of therapy.