Biocatalytic refining of polysaccharides from brown seaweeds

Hreggviðsson, Guðmundur Ó.; Karlsson, Eva Nordberg; Tøndervik, Anne; Aachmann, Finn Lillelund; Dobruchowska, Justyna M.; Linares-Pastén, Javier A.; Christensen, Monica Daugbjerg; Moneart, Antoine; Kristjansdottir, Thordis; Sletta, Håvard; Friðjónsson, Ólafur H.; Aasen, Inga Marie

doi:10.1016/b978-0-12-817943-7.00016-0

Cited by 9 publications

(13 citation statements)

References 178 publications

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“…Alginates are linear block co-polymers composed of a 1,4-linked β-D-mannuronic acid (M) with a 4C1 ring conformation and an α-L-guluronic acid (G) with a 4C1 conformation, both in the pyranose conformation and present in varying amounts in the polymer structure [ 92 ]. Natural alginates have no regular repeating sequences, and the monomers can be arranged in homogeneous blocks of varying lengths (G-, M-, and MG-blocks) or in random patterns [ 93 ]. Cong et al [ 93 ] demonstrated that H. fusiformis alginates were rich in M blocks and the average molecular weights of 04S2P-S and commercial alginate (Alg-S) were 55.5 kDa and 557 kDa, respectively.…”

Section: Resultsmentioning

confidence: 99%

“…Natural alginates have no regular repeating sequences, and the monomers can be arranged in homogeneous blocks of varying lengths (G-, M-, and MG-blocks) or in random patterns [ 93 ]. Cong et al [ 93 ] demonstrated that H. fusiformis alginates were rich in M blocks and the average molecular weights of 04S2P-S and commercial alginate (Alg-S) were 55.5 kDa and 557 kDa, respectively. Sulfation modification of Alg-S resulted in higher molecular weights.…”

Section: Resultsmentioning

confidence: 99%

“…Moreover, the polymer composition, as measured by the M/G ratio, particularly the length of the G-block, is critical in determining the physicochemical properties of alginate [ 94 ]. In the presence of divalent cations such as calcium, barium, and strontium, G-blocks can create strong hydrogels via coordination of the divalent cations in cavities formed by two contiguous G-blocks [ 93 ].…”

Section: Resultsmentioning

confidence: 99%

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Hizikia fusiformis: Pharmacological and Nutritional Properties

Meinita

Harwanto

Sohn

et al. 2021

Foods

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The brown seaweed Hizikia fusiformis (syn. Sargassum fusiforme), commonly known as “Hijiki”, has been utilized in traditional cuisine and medicine in East Asian countries for several centuries. H. fusiformis has attracted much attention owing to its rich nutritional and pharmacological properties. However, there has been no comprehensive review of the nutritional and pharmacological properties of H. fusiformis. The aim of this systematic review was to provide detailed information from the published literature on the nutritional and pharmacological properties of H. fusiformis. A comprehensive online search of the literature was conducted by accessing databases, such as PubMed, SpringerLink, ScienceDirect, and Google Scholar, for published studies on the nutritional and pharmacological properties of H. fusiformis between 2010 and 2021. A total of 916 articles were screened from all the databases using the preferred reporting items for systematic reviews and meta-analyses method. Screening based on the setdown criteria resulted in 59 articles, which were used for this review. In this review, we found that there has been an increase in the number of publications on the pharmacological and nutritional properties of H. fusiformis over the last 10 years. In the last 10 years, studies have focused on the proximate, mineral, polysaccharide, and bioactive compound composition, and pharmacological properties, such as antioxidant, anticancer, antitumor, anti-inflammatory, photoprotective, neuroprotective, antidiabetic, immunomodulatory, osteoprotective, and gastroprotective properties of H. fusiformis extracts. Overall, further studies and strategies are required to develop H. fusiformis as a promising resource for the nutrition and pharmacological industries.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Hizikia fusiformis: Pharmacological and Nutritional Properties

Meinita

Harwanto

Sohn

et al. 2021

Foods

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“…Type 3, however, includes α-l-fucosidase, which are exo-acting enzymes that catalyze the degradation of α-l-fucosyl bonds at the non-reducing termini, releasing fucose from the backbone of fucoidan [75]. These enzymes occur in different GH-families in the CAZy database, of which the enzymes classified under GH29 are structurally related to the GH107 endofucoidanases [8].…”

Section: Fucoidanmentioning

confidence: 99%

Extraction and Modification of Macroalgal Polysaccharides for Current and Next-Generation Applications

et al. 2020

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Marine macroalgal (seaweed) polysaccharides are highly promising for next-generation applications in several industries. However, despite the reported comprehensive potential of these polysaccharides, commercial products are scarce on the market. Seaweed cultivations are increasing in number and production quantity, owing to an elevated global trend of utilization interest in seaweed. The extraction of polysaccharides from seaweed generally generates low yields, but novel methods are being developed to facilitate and improve the extraction processes. Current areas of applications for seaweed polysaccharides mainly take advantage of the physicochemical properties of certain polysaccharides, such as gelling, thickening and emulsifying. However, many of the numerous bioactivities reported are still only at research level and lack clinical evidence for commercialization. It has been suggested the construction of smaller units may generate better defined molecules that are more suitable for biomedical applications. Enzymatic modification is a promising tool for the generation of more defined, targeted biomolecules. This review covers; structural differences between the most predominant marine algal polysaccharides, extraction processes, modification alternatives, as well as a summary of current and potential next-generation application areas.

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“…This has led to a focus on the use of macroalgae in microbial anaerobic digestion for biogas production [15], and the production of bio-oil through thermochemical processes such as pyrolysis or hydrothermal liquefaction [16,17]. In order to utilize macroalgae as a feedstock in biorefineries, there is a need for efficient and cost-effective pre-treatment methodologies [18], polysaccharide degrading enzymes [19,20], and versatile fermentative microorganisms that can utilize mixed carbon sources [21,22]. In recent years, there have been efforts to identify natural strains or genetically engineer microorganisms with the ability to ferment sugars from seaweed into biofuels, including ethanol [23][24][25] and butanol [26,27].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Laminaria Digitata Hydrolysate for the Production of Bioethanol and Butanol by Fermentation

et al. 2023

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Seaweeds (macroalgae) are gaining attention as potential sustainable feedstock for the production of fuels and chemicals. This comparative study focuses on the characterization of the microbial production of alcohols from fermentable carbohydrates in the hydrolysate of the macroalgae Laminaria digitata as raw material. The potential of a hydrolysate as a carbon source for the production of selected alcohols was tested, using three physiologically different fermentative microbes, in two main types of processes. For the production of ethanol, Saccharomyces cerevisiae was used as a benchmark microorganism and compared with the strictly anaerobic thermophile Thermoanaerobacterium strain AK17. For mixed production of acetone/isopropanol, butanol, and ethanol (A/IBE), three strictly anaerobic Clostridium strains were compared. All strains grew well on the hydrolysate, and toxicity constraints were not observed, but fermentation performance and product profiles were shown to be both condition- and strain-specific. S. cerevisiae utilized only glucose for ethanol formation, while strain AK17 utilized glucose, mannitol, and parts of the glucan oligosaccharides. The clostridia strains tested showed different nutrient requirements, and were able to utilize glucan, mannitol, and organic acids in the hydrolysate. The novelty of this study embodies the application of different inoculates for fermenting a common brown seaweed found in the northern Atlantic Ocean. It provides important information on the fermentation properties of different microorganisms and pinpoints the value of carbon source utilization when selecting microbes for efficient bioconversion into biofuel and chemical products of interest.

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Biocatalytic refining of polysaccharides from brown seaweeds

Cited by 9 publications

References 178 publications

Hizikia fusiformis: Pharmacological and Nutritional Properties

Hizikia fusiformis: Pharmacological and Nutritional Properties

Extraction and Modification of Macroalgal Polysaccharides for Current and Next-Generation Applications

Evaluation of Laminaria Digitata Hydrolysate for the Production of Bioethanol and Butanol by Fermentation

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