Biobehavioral research on nicotine use in women

Pomerleau, Cynthia S.; Pomerleau, Ovide F.; García, Alfredo

doi:10.1111/j.1360-0443.1991.tb01802.x

Cited by 39 publications

(24 citation statements)

References 36 publications

(29 reference statements)

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“…These findings are consistent with those of Pomerleau et al, who reported possible gender differences in physical response to nicotine, resulting in differences in withdrawal and reduced quit rates among women. 4 We found no gender differences at the higher levels of self-reported emotional and physical dependence. This suggests that, if women perceived their nicotine dependence at baseline to be greater than did men, this perception did not affect sustained quit rates.…”

Section: Discussionmentioning

confidence: 40%

Gender differences in smoking cessation after 3 years in the Lung Health Study.

et al. 1995

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OBJECTIVES. An analysis of gender differences in smoking cessation was conducted among 3923 participants in the Special Intervention group of the Lung Health Study. This report focuses on gender differences in sustained quit rates at 12 and 36 months. METHODS. Special Intervention participants were offered a 12-session, 12-week smoking cessation program using nicotine gum and were followed for 3 years. Self-reported smoking status was validated with carbon monoxide and salivary cotinine. RESULTS. Men had higher sustained quit rates at 12 and 36 months; gender differences were found in baseline variables that also predicted sustained abstinence; and controlling for selected baseline variables reduced the association between gender and sustained abstinence. When other variables were controlled, gender predicted sustained abstinence at 36 months (odds ratio [OR] = 1.24, 95% confidence interval [CI] = 1.04, 1.48) but not 12 months (OR = 1.08, 95% CI = 0.92, 1.27), reflecting more late relapse among women. CONCLUSIONS. Demographics and smoking history were more important than gender per se in sustained smoking cessation in the Lung Health Study. Programs tailoring smoking cessation by gender need to include coping skills for problems associated with less education and social support and for improving persistence with quit attempts.

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Section: Discussionmentioning

confidence: 40%

Gender differences in smoking cessation after 3 years in the Lung Health Study.

et al. 1995

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“…the number of cigarettes smoked [8,[11][12][13] as well as alcohol consumption [13,14] are important predictors of smoking abstinence. The result obtained from our final multivariate model that male gender predicted smoking abstinence could be explained by previous findings showing that gender differences in nicotine metabolism [26] as well as concerns about weight gain might deter more women from quitting than men [27].…”

Section: Discussionmentioning

confidence: 80%

Predictors of adolescent smoking cessation and smoking reduction

Haug

Schaub

Schmid

2014

Patient Education and Counseling

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OBJECTIVE: To investigate the processes of change, demographic, health-and smokingrelated predictors of both smoking cessation and smoking reduction in adolescents. METHODS: Data were drawn from a sample of 755 adolescent smokers who participated in a study testing the efficacy of a text messaging-based intervention for smoking cessation. Demographic, health-and smoking-related variables were assessed at baseline. Five processes of smoking cessation, derived from the Transtheoretical Model and the Social Cognitive Theory, as well as outcome measures were assessed at 6-month follow up. Univariate and multivariate regression analyses were conducted to identify baseline and process variables to predict smoking abstinence and smoking reduction. RESULTS: Male gender (OR=0.43, p<.01), lower alcohol consumption (OR=0.90, p=.05) and a lower number of cigarettes smoked per day at baseline (OR=0.87, p<.01) predicted smoking abstinence. Baseline physical activity predicted smoking reduction (OR=1.04, p=.03). None of the examined process variables significantly predicted smoking abstinence. The process variable "counter-conditioning" predicted smoking reduction (OR=1.46, p=.03). CONCLU-SIONS: Baseline predictors of smoking cessation differ from predictors of smoking reduction. Dynamic or modifiable variables play an important role in predicting adolescent smoking cessation. PRACTICE IMPLICATIONS: Counter-conditioning might be an important element in adolescent smoking cessation interventions. of the 10 examined processes only "counter-conditioning" was effective in changing adolescent smoking behavior. DOIThe aims of this study were to investigate a comprehensive set of demographic, health-and smokingrelated predictors of both smoking cessation and smoking reduction in adolescents. Furthermore, we tested whether the use of various processes of change derived from major theoretical models for adolescent smoking cessation predicted smoking cessation or reduction. The results of this study might increase our understanding of how specific intervention elements and participants` characteristics may influence adolescent smoking cessation. Methods ParticipantsThe data for this study were collected within the randomized controlled trial "Efficacy of a text present in the school classes, of whom 2638 (99.3%) completed the assessment. Afterwards, the students were invited to complete an online screening. The survey included the assessment of demographic data, alcohol consumption, weekly physical activity, tobacco smoking status, number of smoking friends and ownership of a mobile phone. Using these data, daily or occasional smoking students who owned a mobile phone were invited to participate in a study testing the efficacy of a text messaging based smoking cessation intervention. After receiving informed consent online, the following smoking-related variables were assessed: stage of change, number of cigarettes smoked per day, past quit attempts, and age of smoking onset. From 1012 eligible persons, who met the inclusion c...

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“…Although men smoke more than women, the decline in smoking prevalence has been slower for women [38]. Women have less success quitting smoking, and are more likely to relapse, than men [2].…”

Section: Introductionmentioning

confidence: 99%

Sex differences in anxiety-like behavior and locomotor activity following chronic nicotine exposure in mice

Caldarone

King

Picciotto

2008

Neuroscience Letters

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Smoking appears to increase overall levels of stress, despite self-reports that men and women smoke to control symptoms of anxiety. The overall incidence of anxiety disorders is also significantly higher in women. This study examined whether behavioral sensitivity to chronic nicotine varies across sexes in mice. Male and female C57BL/6J mice were exposed chronically to nicotine in the drinking water (50, 100, or 200 µg/ml) and tested for locomotor activation and anxiety-like behavior in the elevated plus maze (EPM). Female mice were less sensitive to locomotor activation. Whereas both males and females showed increases in locomotor activity at the highest (200 µg/ml) concentration of nicotine, only males showed locomotor activation at the middle (100 µg/ml) concentration. The decreased sensitivity in females could not be explained by reduced nicotine intake compared to males. In the EPM, nicotine produced an anxiogenic-like response in females, but had no effect in males. Treatment with the high (200 µg/ml) dose of nicotine reduced the amount of time spent in the open arms of the EPM in female, but not male mice. No differences in the anxiogenic-like response to chronic nicotine was observed between β2-subunit knockout and wildtype mice, suggesting that β2-subunit containing nicotinic receptors do not mediate the anxiogenic-like response to chronic nicotine in females. This shows that female mice have an anxiogenic-like response to chronic nicotine, but are less sensitive to nicotine's psychostimulant properties, which may be related to the increased relapse to smoking following abstinence in women.

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Biobehavioral research on nicotine use in women

Cited by 39 publications

References 36 publications

Gender differences in smoking cessation after 3 years in the Lung Health Study.

Gender differences in smoking cessation after 3 years in the Lung Health Study.

Predictors of adolescent smoking cessation and smoking reduction

Sex differences in anxiety-like behavior and locomotor activity following chronic nicotine exposure in mice

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