Biobanks for life sciences and personalized medicine: importance of standardization, biosafety, biosecurity, and data management

Müller, Heimo; Dagher, Georges; Loibner, Martina; Stumptner, Cornelia; Kungl, Penelope; Zatloukal, Kurt

doi:10.1016/j.copbio.2019.12.004

Cited by 61 publications

(45 citation statements)

References 53 publications

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“…Among its various roles, the biobank guarantees the quality of the procedures for collecting, transporting, processing, storing and making available biological samples in compliance with the rules of good practice and regulations [6].…”

Section: Introductionmentioning

confidence: 99%

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Study of laboratory staff’ knowledge of biobanking in Côte d’Ivoire

et al. 2020

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Background A biobank is a structure which collects and manages biological samples and their associated data. The collected samples will then be made available for various uses. The sharing of those samples raised ethical questions which have been answered through specific rules. Thus, a Biobank functioning under tight ethical rules would be immensely valuable from a scientific and an economic view point. In 2009, Côte d’Ivoire established a biobank, which has been chosen to house the regional biobank of Economic Community of West African States (ECOWAS) countries in 2018. To ensure optimal and efficient use of this biobank, the scientific community must be aware of its existence and its role. It was therefore necessary to evaluate the knowledge of laboratories staff on the role and activities of a biobank. Methods This descriptive study was done by questioning staff from laboratories working on human’s health, animals or plants. The laboratories were located in southern Côte d’Ivoire. Results A total of 205 people completed the questionnaire. Of these 205 people, 34.63% were biologists, 7.32% engineers, 48.78% technicians and 9.27% PhD students. The average length of work experience was 10.11 ± 7.83 years. In this study, 43.41% of the participants had never heard of biobanking. Only 48.78% of participants had a good understanding of the role of a biobank. Technicians and PhD students were less educated on the notion of biobank (p < 0.000001). Although biologists were more educated on this issue, 21.13% of them had a misconception of biobank. Good knowledge of the role of a biobank was not significantly related to the work experience’s length (p > 0.88). Conclusion The level of knowledge of laboratory staff about biobanking needs to be improved. Training on the role, activities and interests of the biobank is important.

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Section: Introductionmentioning

confidence: 99%

“…A biobank is defined as a structure that receives, processes, stores and makes available biological samples with their associated data for research and clinical care purposes. Samples can be from humans, animals, plants or the environment [ 3 – 6 ].…”

Section: Introductionmentioning

confidence: 99%

Study of laboratory staff’ knowledge of biobanking in Côte d’Ivoire

et al. 2020

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“… 36 Verification of these aspects of quality and standardization of the processes associated with collection and storage of biospecimens and data is increasingly recognized to be important. 37 Quality control (QC) approaches to determine the quality of extracted derivatives such as DNA, RNA, and proteins are well recognized in the laboratory. In addition several organizations have created internationally recognized biobanking standards, including the recent development of the ISO 20387 standard, and associated external quality assurance (QA) programs for biobanks that provide assurance of a known standard and level of quality around the broader “biobanking processes.” 38 …”

Section: Biobanking For Research – the Research Perspectivementioning

confidence: 99%

Biobanking for Cancer Biomarker Research: Issues and Solutions

Matzke

Watson

2020

Biomark�Insights

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Biomarkers are critical tools that underpin precision medicine. However there has been slow progress and frequent failure of biomarker development. The root causes are multifactorial. Here, we focus on the need for fast, efficient, and reliable access to quality biospecimens as a critical area that impacts biomarker development. We discuss the past history of biobanking and the evolution of biobanking processes relevant to the specific area of cancer biomarker development as an example, and describe some solutions that can improve this area, thus potentially accelerating biomarker research.

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“…A biobank is de ned as a structure that receives, processes, stores and makes available biological samples and associated data for research and clinical care purposes. Samples can be of human, animal, plant and environmental origin [3][4][5][6].…”

Section: Introductionmentioning

confidence: 99%

“…In its operation, the biobank guarantees the quality of the procedures for collecting, transporting, processing, storing and making available biological samples in compliance with the rules of good practice and regulations [6].…”

Section: Introductionmentioning

confidence: 99%

Study of laboratory staff' knowledge of biobanking in Côte d'Ivoire

Kintossou

N'Dri

Money

et al. 2020

Preprint

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Background: The biobank is a structure that manages and makes available biological resources. The biobank has medical, scientific and economic interests in an ethical manner. In 2009, Côte d'Ivoire established a biobank, which has housed the regional biobank of Economic Community of West African States (ECOWAS) countries since 2018. To ensure optimal and efficient use of this biobank, scientific stakeholders must be aware of its existence and role. It was therefore necessary to assess the knowledge of laboratory staff on the role and activities of a biobank.Methods: This is a descriptive study conducted with staff of human, animal and plant health laboratories located in southern Côte d'Ivoire. Results: A total of 205 people agreed to complete the proposed questionnaire. Of these, 34.63% are biologists, 7.32% engineers, 48.78% technicians and 9.27% PhD students. The average professional experience was 10.11 ± 7.83 years. Respectively, 47.32% and 43.41% have never heard of biocollection and biobank. Only 48.78% of participants had a good understanding of the role of a biobank. Technicians and PhD students were less educated on the notion of biobank (p<0.000001). Biologists, although they were more educated on this issue, 21.13% of them had a misconception of biobank. Good knowledge of the role of a biobank was not significantly related to the duration of professional experience (p>0.88). Conclusion: The level of knowledge of laboratory staff about biobanking remains to be improved. Training on the role, activities and interests of the biobank is important.

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Biobanks for life sciences and personalized medicine: importance of standardization, biosafety, biosecurity, and data management

Cited by 61 publications

References 53 publications

Study of laboratory staff’ knowledge of biobanking in Côte d’Ivoire

Study of laboratory staff’ knowledge of biobanking in Côte d’Ivoire

Biobanking for Cancer Biomarker Research: Issues and Solutions

Study of laboratory staff' knowledge of biobanking in Côte d'Ivoire

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