Bioavailability and impacts of estrogenic compounds from suspended sediment on rainbow trout (Oncorhynchus mykiss)

Müller, Anne-Katrin; Markert, Nele; Leser, Katharina; Kämpfer, David; Schiwy, Sabrina; Riegraf, Carolin; Buchinger, Sebastian; Gan, Lin; Abdallah, Ali T.; Denecke, Bernd; Segner, Helmut; Brinkmann, Markus; Crawford, Sarah E.; Hollert, Henner

doi:10.1016/j.aquatox.2020.105719

Cited by 17 publications

(5 citation statements)

References 50 publications

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“…The estrogenic activity determined at other Guanabara Bay stations ranged from 0.1 to 0.3 ng g −1 E2‐EQ (Exhibit 3). Differential endocrine disrupting compound distribution, transport, and bioavailability, as well as local hydrodynamics, may also influence lower responses (Müller et al., 2021; Ding et al., 2019), especially as endocrine disrupting compound sediment bioavailability is a highly complex process that involves dissolution, diffusion, adsorption, desorption, and degradation (Liu et al., 2017; Cheng & Hua, 2018; Galletti et al., 2019), and is also influenced by grain size (Cauwet, 1987).…”

Section: Resultsmentioning

confidence: 99%

“…Sediments, in particular, comprise chemical pollutant deposits and sources (Ali et al., 2018; Gebremariam et al., 2012; Müller et al., 2021), as ions can be removed and/or released from this matrix through adsorption and desorption processes, as well as transported and stored ( Müller et al., 2021). These processes depend on sediment characteristics, the local environment (i.e., tidal cycles, waves, and currents), and available pollutants, all of which must be considered in environmental exposure assessments (Catanzaro et al., 2004; Ding et al., 2019).…”

Section: Introductionmentioning

confidence: 99%

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Estrogenic activity and acute toxicity assessments of sediments from a chronically polluted estuarine area in southeastern Brazil

Santos,

Nascimento,

Argolo

et al. 2023

Environmental Quality Mgmt

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Compounds displaying estrogenic potential can lead to serious negative aquatic ecosystem impacts, and exposure to mixtures of endocrine disruptors present in environmental matrices with very complex characteristics, including sediments, can cause serious risks to biota, animals, and humans. Within this perspective, the aim of the present study was to assess estrogenic activity and toxicity in sediments sampled from Guanabara Bay, the most important, although chronically polluted, estuary in southeastern Brazil. To this end, estrogenic activity determinations were performed by the yeast estrogen screen (YES) assay, and acute toxicity assays were carried out employing Vibrio fischeri. Estrogenic activity was quantified up for 8.7 ng g−1 in E2‐EQ, although high levels of cytotoxicity (up to 95%) were observed and might have hindered the determination of the real estrogenic potential in most samples. Acute toxicity to V. fischeri ranged from 0 to 45.21%. These results point to potential deleterious effects caused by micropollutants and underline the urgency of continuous monitoring of the degradation degree of the Guanabara Bay estuary.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Estrogenic activity and acute toxicity assessments of sediments from a chronically polluted estuarine area in southeastern Brazil

Santos,

Nascimento,

Argolo

et al. 2023

Environmental Quality Mgmt

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“…Finally, external factors, such as environmental contaminants in sediments, should be of concern, given that several EDCs accumulate in this matrix, and minimal data are available regarding the bioavailability and effects of these EDCs in association with sediments in the environment. For instance, chemicals are released from sediment during floods and become bioavailable to aquatic biota (Müller et al, 2021).…”

Section: Oncorhynchus Mykissmentioning

confidence: 99%

Studies of Endocrine Disruptors: Nonylphenol and Isomers in Biological Models

Parra-Guerra

Acevedo-Barrios

2023

Enviro Toxic and Chemistry

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Certain emerging pollutants are among the most widely used chemicals globally, causing widespread concern in relation to their use in products devoted to cleaniness and asepsis. Nonylphenol ethoxylate (NPEOn) is one such contaminant, along with its degradation product, nonylphenol, an active ingredient presents in nonionic surfactants used as herbicides, cosmetics, paints, plastics, disinfectants, and detergents. These chemicals and their metabolites are commonly found in environmental matrices. Nonylphenol and NPEOn, used, are particularly concerning, given their role as endocrine disruptors chemical and possible neurotoxic effects recorded in several biological models, primarily aquatic organisms. Limiting and detecting these compounds remain of paramount importance. The objective of the present review was to evaluate the toxic effects of nonylphenol and NPEOn in different biological models.

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“…In research by Müller et al [ 98 ] juvenile rainbow trouts ( O. mykiss ) were exposed to the estrogenic compounds deposited in the bottom sediments of the Luppe river (Saxony, Germany). During the study, 2-, 4- and 8-fold dilutions of the sediments were used containing NP and estrone.…”

Section: Impact On Metabolismmentioning

confidence: 99%

Estrogen Receptors Mediated Negative Effects of Estrogens and Xenoestrogens in Teleost Fishes—Review

Wojnarowski

Cholewińska

Palić

et al. 2022

IJMS

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Estrogen receptors (ERs) play a key role in many biochemical and physiological processes, that are involved in maintaining organism homeostasis. At the most basic level, they can be divided into nuclear estrogen receptors and membrane estrogen receptors that imply their effect in two ways: slower genomic, and faster non-genomic. In these ways, estrogens and xenoestrogens can negatively affect animal health and welfare. Most of the available literature focuses on human and mammalian physiology, and clearly, we can observe a need for further research focusing on complex mutual interactions between different estrogens and xenoestrogens in aquatic animals, primarily fishes. Understanding the mechanisms of action of estrogenic compounds on the ERs in fishes and their negative consequences, may improve efforts in environmental protection of these animals and their environment and benefit society in return. In this review, we have summarized the ER-mediated effects of xenoestrogens and estrogens on teleost fishes metabolism, their carcinogenic potential, immune, circulatory, and reproductive systems.

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Bioavailability and impacts of estrogenic compounds from suspended sediment on rainbow trout (Oncorhynchus mykiss)

Cited by 17 publications

References 50 publications

Estrogenic activity and acute toxicity assessments of sediments from a chronically polluted estuarine area in southeastern Brazil

Estrogenic activity and acute toxicity assessments of sediments from a chronically polluted estuarine area in southeastern Brazil

Studies of Endocrine Disruptors: Nonylphenol and Isomers in Biological Models

Estrogen Receptors Mediated Negative Effects of Estrogens and Xenoestrogens in Teleost Fishes—Review

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