2015
DOI: 10.1007/698_2015_417
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Bioassays Currently Available for Evaluating the Biological Potency of Pharmaceuticals in Treated Wastewater

Abstract: Water deprivation with regard to quantity and quality is one of the most important environmental problems of the century. The increasing demand of water resources puts pressure on the utilization of alternative sources such as treated wastewater. In the context of "reduce, reuse, and recycle," the inclusion of treated wastewater in the water cycle seems a promising practice for water management. The lack of general acceptance of stakeholders and public, however, still hinders the widespread application of wast… Show more

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Cited by 3 publications
(2 citation statements)
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References 139 publications
(152 reference statements)
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“…It has been included in the list of priority hazardous compounds [9]. Diclofenac has been found to be toxic at the low μg/L levels in chronic exposures of different organisms like fish and mussels, as reviewed in Vasquez et al [10]. Interestingly, a permanent shift of the microbial community composition of a wastewater treatment bioreactor was observed after an exposure to diclofenac at 50 pg/L [11].…”
Section: Introductionmentioning
confidence: 99%
“…It has been included in the list of priority hazardous compounds [9]. Diclofenac has been found to be toxic at the low μg/L levels in chronic exposures of different organisms like fish and mussels, as reviewed in Vasquez et al [10]. Interestingly, a permanent shift of the microbial community composition of a wastewater treatment bioreactor was observed after an exposure to diclofenac at 50 pg/L [11].…”
Section: Introductionmentioning
confidence: 99%
“…However, this quickly leads to immense resource requirements, especially for heterogeneous mixtures and investigations of apical effects on whole organisms. Numerous bioassays now exist for APIs found in effluents (Vasquez et al, 2016), and EDA is being applied to surface waters, sediments, and even biological tissues (Simon et al, 2015). However, if the TIE or EDA is focused on a particular group of chemicals with similar modes of action, fewer simpler and more specific high‐throughput assays (e.g., receptor‐activation assays) can be used.…”
Section: What Are the Advances In Our Understanding Of The Ecotoxicol...mentioning
confidence: 99%