Bioassay guided fractionation of extracts from flowers of Bellis perennis L. for their anticancer activity

Karakas, F Pehlivan; Karakaş, Alper; Mshvildadze, Vakhtang; Legault, Jean; Pichette, André; Türker, Arzu Uçar

doi:10.1055/s-0031-1282974

Cited by 1 publication

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“…"Daisy (Bellis perennis L.) is a traditional medicinal plant from the Asteraceae family. It is used to treat eye diseases, eczema, gastritis, enteritis, diarrhoea, rheumatism, upper respiratory tract infections and to heal wounds" [1][2][3][4]. "It is native to western, central and northern Europe, but is commonly found as an invasive plant in North America" [5].…”

Section: Introductionmentioning

confidence: 99%

Tyrosinase Inhibition, Antioxidant and Antibacterial Activity of Commercial Daisy Extract (Bellis perennis)

Karić

Horozić

Pilipović

et al. 2023

J. Pharm. Res. Int.

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Extracts obtained from plant material have widely applied in the chemical and pharmaceutical industries because they contain significant concentrations of biologically active substances. Commercial daisy extract (Bellis perennis) was used in this paper for in vitro testing of tyrosinase enzyme inhibition, and antioxidant and antimicrobial activity. Inhibition of the tyrosinase enzyme was determined by monitoring dopachrome formation at a wavelength of 492 nm. Antioxidant activity was tested using FRAP and DPPH methods, while antibacterial activity was tested by diffusion technique on reference strains from the ATCC collection. The results showed that daisy extract inhibits tyrosinase enzyme in a dose-dependent manner. The extract effectively neutralized DPPH radicals and also showed good reducing ability. Bacterial strains used for in vitro antimicrobial activity testing did not show sensitivity to the extract concentrations used in this study.

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