Abstract:A simple, rapid, precise, sensitive, and reproducible reverse-phase high-performance liquid chromatography (RPHPLC) LCMS/MS method has been developed for the bioanalytical method for Selinexor with D6-Selinexor as Internal Standard in the pharmaceutical dosage form. Chromatographic separation of Selinexor was achieved on Waters Alliance-e2695, by using X-Bridge phenyl, 150x4.6mm, 3.5μm column, and the mobile phase containing 0.1% Formic acid & Acetonitrile in the ratio of 80:20% v/v. The flow rate was 1.0 … Show more
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