Bioadhesive hydrogels for cosmetic applications

Abstract

Physico-chemical and sensory techniques enabled the identification of bioadhesive hydrogel formulations with positive characteristics for cosmetic applications. Formulations which combined carbomer homopolymer type C with xanthan gum or with carbomer copolymer type B were the most promising for bioadhesive skin products. Caffeine release profiles of selected formulations were not statistically different. Both hydrogels gradually released the active ingredient, reaching approximately 80% within the first 5 h, and their profiles were well described by the Higuchi model. In this context, it could be concluded that the selected hydrogels are suitable bioadhesive hydrogel formulations for cosmetic application on the skin.

Trans-resveratrol-loaded nonionic lamellar liquid-crystalline systems: structural, rheological, mechanical, textural, and bioadhesive characterization and evaluation of in vivo anti-inflammatory activity

“…[68][69][70] Bioadhesive force values are shown in Table 4. Bioadhesive force showed significant differences (P,0.05) between mean values of the different formulations and between those of the loaded and unloaded formulations.…”

Dynamic sensory characterization of cosmetic creams during application using Temporal Check-All-That-Apply (TCATA) questions

“…Petrolatum is a common occlusive agent used to reduce transepidermal water loss, which is typically associated with a thicker consistency and greasy sensations (Nacht, Close, Yeung, & Gans, 1981). Finally, xantham gum has been related to stickiness and whitening sensations when applied on the skin (Parente, Ochoa, Ares, Russo, & Jiménez-Kairuz, 2015).…”

Synthesis of poly(acrylic acid)–Fe3+/gelatin/poly(vinyl alcohol) triple‐network supramolecular hydrogels with high toughness, high strength and self‐healing properties

“…Hydrogels are important soft biomaterials composed of polymers with network structure and water . They have been widely used in drug delivery, tissue engineering, cosmetics, agriculture, etc. However, the existing hydrogels have poor mechanical properties, such as insufficient strength and brittleness.…”