Bioactivity of Excoecaria agallocha leaf extract against Pseudomonas aeruginosa infection in Labeo rohita

Divya, D.; Beulah, G.; Rao, K. Govinda; Sravya, M. V. N.; Simhachalam, G.; Krishna, Malini; Kumar, N. S. Sampath

doi:10.1080/10454438.2022.2029792

Cited by 4 publications

(2 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Fraction A of column and band AM2 of TLC has elevated antibacterial and antioxidant activity than the crude methanol extract. This was in par with the studies of (Moovendhan et al 2015 ) in A.marina, (Beulah et al 2021 ) in S.maritima and (Divya et al 2022 ) in E.agallocha . The compounds that are responsible for the antimicrobial activity are characterized and structurally elucidated by GC–MS (Konappa et al 2020 ).…”

Section: Discussionsupporting

confidence: 85%

Anti-pathogenicity of Acanthus ilicifolius leaf extracts against A. hydrophila infection in Labeo rohita fingerlings

Sravya,

Simhachalam,

Kumar

et al. 2023

AMB Expr

Self Cite

View full text Add to dashboard Cite

Antibiotic resistance has become one of the inevitable barrier in aquaculture disease management. Herbal drugs has evolved to be the novel ways of combating drug resistant pathogens. In the current investigation, leaf extracts of mangrove plant, Acanthus ilicifolius were assessed for in vitro studies, among the selected four extracts, methanol extract has expressed highest antibacterial activity against P .aeruginosa (4 ± 0.3 mm), A. hydrophila (5.9 ± 0.5 mm), S. aureus (3.5 ± 0.7 mm) and B. subtilis (2.9 ± 0.5 mm) and antioxidant activity, DPPH (81.3 ± 1.0 AAEµg/ml) and FRAP (139.1 ± 1.5 AAEµg/ml).TPC and TFC were higher in the methanolic extract and has exhibited positive correlation with both DPPH and FRAP assays. Considering the in vitro efficiency, methanol extract was purified successively by column and thin layer chromatography and characterisation by GC–MS unveiled the presence of 2-Propanethiol, Trimethylphosphine, Pentanoyl chloride, Dimethylhydroxymethylphosphine and Propanedinitrile, ethylidene. A. hydrophila infected L. rohita fingerlings has survival percentage 81% and 94% in extract treated groups over 0% in negative control and 71% in positive control.

show abstract

Section: Discussionsupporting

confidence: 85%

Anti-pathogenicity of Acanthus ilicifolius leaf extracts against A. hydrophila infection in Labeo rohita fingerlings

Sravya,

Simhachalam,

Kumar

et al. 2023

AMB Expr

Self Cite

View full text Add to dashboard Cite

show abstract

“…P. aeruginosa cause red skin infection in Oreochromis mossambicus [ 71 ]. Divya et al [ 72 ] stated that P. aeruginosa cause friable liver, gill necrosis, abdominal distension, splenomegaly and hemorrhagic septicemia in Indian major carp Labeo rohita . Kukułowicz et al [ 73 ] and Sivaraman et al [ 74 ] isolated S. aureus from edible fish.…”

Section: Resultsmentioning

confidence: 99%

Evaluation of Phytochemical Screening, Pigment Content, In Vitro Antioxidant, Antibacterial Potential and GC-MS Metabolite Profiling of Green Seaweed Caulerpa racemosa

et al. 2023

View full text Add to dashboard Cite

Exploration of seaweeds to unravel their bioactive metabolites from the perspective of wider applications gained substantial importance. The present study was performed to investigate the total phenolic, flavonoid, tannin content, antioxidant activity and antibacterial potential of various solvent extracts of green seaweed Caulerpa racemosa. The methanolic extract showed higher phenolic (11.99 ± 0.48 mg gallic acid equivalents/g), tannin (18.59 ± 0.54 mg tannic acid equivalents/g) and flavonoid (33.17 ± 0.76 mg quercetin equivalents/g) content than other extracts. Antioxidant activity was determined by using 2,2-diphenylpicrylhydrazyl (DPPH) and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay with different concentrations of C. racemosa extracts. The methanolic extract showed higher scavenging potential in both the DPPH and ABTS activity with the inhibition value of 54.21 ± 1.39% and 76.62 ± 1.08%, respectively. Bioactive profiling was also identified by using Gas chromatography-mass spectrometry (GC-MS) and Fourier transform infrared (FT-IR) techniques. These studies revealed the presence of valuable bioactive compounds in C. racemosa extracts and these compounds might be responsible for antimicrobial, antioxidant, anticancer and anti-mutagenic properties. Major compounds identified in GC-MS were 3,7,11,15-Tetramethyl-2-hexadecen-1-ol, 3-hexadecene and Phthalic acid. In terms of antibacterial activity, C. racemosa has promising antibacterial potential against aquatic pathogens Aeromonas hydrophila, Aeromonas veronii and Aeromonas salmonicida. Further evaluation studies focusing aquatic related aspects would reveal the novel bioproperties and applications of C. racemosa.

show abstract

Bioactive Analysis of Antibacterial Efficacy and Antioxidant Potential of Aloe barbadensis Miller Leaf Extracts and Exploration of Secondary Metabolites Using GC–MS Profiling

Palaniyappan

Sridhar

Arumugam

et al. 2023

Appl Biochem Biotechnol

View full text Add to dashboard Cite

Bioactivity of Excoecaria agallocha leaf extract against Pseudomonas aeruginosa infection in Labeo rohita

Cited by 4 publications

References 35 publications

Anti-pathogenicity of Acanthus ilicifolius leaf extracts against A. hydrophila infection in Labeo rohita fingerlings

Anti-pathogenicity of Acanthus ilicifolius leaf extracts against A. hydrophila infection in Labeo rohita fingerlings

Evaluation of Phytochemical Screening, Pigment Content, In Vitro Antioxidant, Antibacterial Potential and GC-MS Metabolite Profiling of Green Seaweed Caulerpa racemosa

Bioactive Analysis of Antibacterial Efficacy and Antioxidant Potential of Aloe barbadensis Miller Leaf Extracts and Exploration of Secondary Metabolites Using GC–MS Profiling

Contact Info

Product

Resources

About