Bioactivity-guided identification and isolation of a major antimicrobial compound in Cistus creticus subsp. creticus leaves and resin “ladano”

Škorić, Marijana; Ćirić, Ana; Budimir, Snežana; Janošević, Dušica; Anđelković, Boban; Todosijević, Marina; Todorović, Slađana; Sokóvić, Marina; Glamočlija, Jasmina; Tešević, Vele; Gašić, Uroš; Mišić, Danijela; Kanellis, Angelos K.

doi:10.1016/j.indcrop.2022.114992

Cited by 5 publications

(5 citation statements)

References 79 publications

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“…However, there is a substantial difference between the yield of polyphenols quantified through the Folin-Ciocalteu method and through HPLC analysis. Some other polyphenolic compounds that could account for this difference, according to the literature [9], could be gallocatechin dimer, naringenin, apigenin, quinic acid, catechin, and gallocatechin catechin.…”

Section: Parametersmentioning

confidence: 99%

“…It is also known as rock rose and it is widely distributed in Europe, mainly in the Mediterranean region, in West Africa, and in Asia [7,8]. It is mainly native to the island of Crete in Greece [9]. The plant species thrives in arid, warm climates, ranging in altitude from sea level to eight hundred meters.…”

Section: Introductionmentioning

confidence: 99%

“…In traditional medicine, various preparations are known and used primarily as anti-inflammatory, hemostatic, tonic, anti-diabetic, antispasmodic, and carminative agents [11]. Contemporary scientific investigations [9,[12][13][14][15] have prioritized the process of isolating and identifying the compounds found in extracts and resins derived from Cistus species. Numerous studies [6,11,[16][17][18][19][20][21] have also examined the biological and pharmacological activity of these compounds, which give rise to the therapeutic properties of the plant.…”

Section: Introductionmentioning

confidence: 99%

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Extraction of Bioactive Compounds from Cistus creticus Leaves and Their Use in the Preparation of Yogurt Desserts

Palaiogiannis,

Athanasiadis,

Chatzimitakos

et al. 2024

Oxygen

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The objective of this study was to determine the optimal conditions for the recovery of bioactive and antioxidant compounds in aqueous solutions of Cistus creticus leaves and then employ the optimal extract for the enrichment of yogurt samples. The optimal conditions were established by a response surface methodology and were determined to be a liquid-to-solid ratio of 48 mL/g at 76 °C for 41 min. The optimum extract yielded TPC 157.17 mg GAE/g dw and TFC 2.38 mg QE/g dw, while FRAP and DPPH values were 1258.52 and 933.67 μmol AAE/g dw, respectively. HPLC‒DAD was utilized to identify and quantify specific polyphenols, like myricetin rhamnoside, in the extract. The optimal extract was then added to yogurt desserts during their preparation at three different concentrations to study how the physicochemical characteristics of the yogurt, as well as the antioxidant capacity added during enrichment, were affected. Statistical analysis of the results was carried out in order to obtain more valid data. It seems that the most suitable concentration for yogurt fortification was 0.1% w/v of the extract as, at this concentration, the yogurts exhibited higher antioxidant capacity, and their physicochemical characteristics were improved.

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Section: Parametersmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Extraction of Bioactive Compounds from Cistus creticus Leaves and Their Use in the Preparation of Yogurt Desserts

Palaiogiannis,

Athanasiadis,

Chatzimitakos

et al. 2024

Oxygen

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“…The major component(s), structure, and also functional groups of the essential oils exhibit a significant role in determining their antimicrobial activity. Although antibacterial activity of essential oils from Helichrysum italicum (Dzamic et al, 2019;Mollova et al, 2020), Inula graveolens (Djenane et al, 2012;Sellem et al, 2020), Cistus creticus (Demetzos et al, 1997;Umarusman et al, 2019;Skoric et al, 2022), Echinacea purpurea (Sharifi-Rad et al, 2018) and Hypericum perforatum (Jianu et al, 2016;Moleriu et al, 2017;Metin & Bicer, 2020) plants have been reported in a variety of food and human pathogenic bacterial disease agents, to the best of our knowledge, no study has been performed on the use of essential oils from these medicinal and aromatic plants against the plant pathogenic bacteria.…”

Section: Introductionmentioning

confidence: 99%

Chemical Compositions and Antibacterial Activities of Essential Oils of Five Aromatic Plants Against Plant Pathogenic Bacterial Disease Agents

GÜMÜŞ,

SOYLU,

KARA

et al. 2022

JAFES

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In this present study, the antibacterial activity and the chemical composition of essential oils from five aromatic plants (Helichrysum italicum, Inula graveolens, Cistus creticus, Echinacea purpurea and Hypericum perforatum) growing in Hatay Province of Turkey were determined. The antibacterial activity of essential oils was tested by disc diffusion method against two different economically important plant bacterial disease agents such as bean halo blight disease agent Pseudomonas syringae pv. phaseolicola and potato soft rot disease agent Pectobacterium carotovorum subsp. carotovorum. The essential oils of five aromatic plants were analyzed by gas chromatography/mass spectrometry (GC/MS). According to GC-MS analysis, 50 components were identified in H. italicum, 42 components in I. graveolens, 48 components in C. creticus, 40 components in E. purpurea and 44 components in H. perforatum. Following GC-MS analysis, neryl acetate (27.17%) and α-pinene (12.3%) in H. italicum, fenchyl (bornyl) acetate (50.33%) and borneol (36.95%) in I. graveolens, α-pinene (19.44%) in C. creticus, caryophyllene oxide (16.94%), α-pinene (16.54%) and carvacrol (6.53%) in E. purpurea and α-pinene (32.15%) in H. perforatum were determined as main components. Based on inhibition zone, the highest antibacterial activities were displayed by H. italicum and H. perforatum EOs against P. syringae pv. phaseolicola (19.33-12.33 mm), respectively. The highest antibacterial activities against P. carotovorum subsp. carotovorum was shown by H. perforatum EO (14.33 mm) followed by C. creticus (10.67 mm) EO. Based on our results, the essential oil of aromatic plants collected from Hatay province has the potential to be applied against important plant bacterial disease agents.

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“…Plants synthesize these secondary metabolites via phenylpropanoid pathways. These compounds are produced by plants to adapt to stress conditions (Skorić et al, 2022)…”

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confidence: 99%

Farkli Çözücüleri̇n Türki̇ye`de Yeti̇şen Ci̇stus Creticus Ekstraklarinin Ki̇myasal Kompozi̇syon, Anti̇oksi̇dan Akti̇vi̇te Ve Anti̇mi̇krobi̇yal Potansi̇yeli̇ne Etki̇si̇

Gedikoğlu

Öztürk

Aytaç

2023

Gıda

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The aims of this study were (1) to assess the extract yield, antioxidant activity, and antimicrobial activity of Cistus creticus extracts obtained from different locations in Türkiye (2) to evaluate the effect of water and methanol solvents on chemical composition, total polyphenol and flavonoid content, IC50, and FRAP values of C. creticus. The extracts had a weak inhibitory effect against tested microorganisms. However, the results of antioxidant assays were very promising. The IC50 values of methanol and water extracts were 13.94 µg/mL and 34.41 µg/mL, respectively. Similarly, the FRAP value of methanolic extract (1.27 M/g) was higher than the water extract (0.72 M/g). The results of HPLC analysis demonstrated that rutin was found only in the methanol extract (13.252%). In addition, the methanol extract had a higher content of quercetin (7.909%), benzoic acid (4.226%), and chlorogenic acid (2.168%), whereas the water extract possessed a higher amount of gallic acid (13.705%).

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Bioactivity-guided identification and isolation of a major antimicrobial compound in Cistus creticus subsp. creticus leaves and resin “ladano”

Cited by 5 publications

References 79 publications

Extraction of Bioactive Compounds from Cistus creticus Leaves and Their Use in the Preparation of Yogurt Desserts

Extraction of Bioactive Compounds from Cistus creticus Leaves and Their Use in the Preparation of Yogurt Desserts

Chemical Compositions and Antibacterial Activities of Essential Oils of Five Aromatic Plants Against Plant Pathogenic Bacterial Disease Agents

Farkli Çözücüleri̇n Türki̇ye`de Yeti̇şen Ci̇stus Creticus Ekstraklarinin Ki̇myasal Kompozi̇syon, Anti̇oksi̇dan Akti̇vi̇te Ve Anti̇mi̇krobi̇yal Potansi̇yeli̇ne Etki̇si̇

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