Abstract:Polymer-ceramic composite coatings on magnesium-based alloys have attracted lots of attention in recent years, to control the speed of degradability and to enhance bioactivity and biocompatibility. In this study, to decrease the corrosion rate in a simulated body fluid (SBF) solution for long periods, to control degradability, and to enhance bioactivity, polycaprolactone-chitosan composite coatings with different percentages of baghdadite (0 wt.%, 3 wt.%, and 5 wt.%) were applied to an anodized AZ91 alloy. Acc… Show more
“…Biomaterial implants such as metals and ceramics can be coated with ceramic or composite coatings made from baghdadite ceramic [ 54 , 100 , 101 ]. Liang et al.…”
Section: Applications Of Baghdadite Ceramicmentioning
“…Biomaterial implants such as metals and ceramics can be coated with ceramic or composite coatings made from baghdadite ceramic [ 54 , 100 , 101 ]. Liang et al.…”
Section: Applications Of Baghdadite Ceramicmentioning
“…In this case, stable support could not be provided in the process of tissue repair, since it may lead to the premature failure of implants. Proper surface modification of the magnesium alloy could control the degradation rate and improve biocompatibility [5][6][7]. The most common surface modification method is to produce protective coatings on magnesium alloys, which mainly include some inorganic coatings and degradable polymer coatings [8].…”
Constructing surface topographies in the micro- or nanometer range is an effective way to improve the biocompatibility of biomaterials. For the present work, anatase coatings with controllable micro/nanoscale characteristics were successfully prepared on an MgZn alloy surface via solvothermal route, and their formation mechanisms are discussed. The features of the as-prepared coatings were characterized using a scanning electron microscope (SEM), a transmission electron microscope (TEM), an atomic force microscope (AFM), X-ray diffraction (XRD), and a contact angle goniometer. The corrosion behavior of the coatings was also evaluated by testing the open circuit potential (OCP) in SBF (Simulated Body Fluid). The results show that a gradual variation of the anatase coating morphologies was obtained through adjusting the solvothermal reaction conditions. With the increase of NH4F concentration in the solution, the cross-combined anatase nanosheets became more dispersed. The micro/nanostructured anatase coatings provide the MgZn alloy with good corrosion resistance, which increased with the density of anatase nanosheets in the coatings. In addition, the coatings exhibit the inhibition of platelet aggregation, and the micro/nano structures can also adsorb endothelial cells.
“…However, the main disadvantage of Mg alloys for medical applications is the rapid and inhomogeneous corrosion in the physiological environment; hence, Mg alloy implants may lose their mechanical integrity before the complete healing of the tissue. In order to solve this problem, surface modifications have been widely carried out to prepare suitable coatings onto Mg alloys as corrosion protective layers, and also to improve their biocompatibility and mechanical stability [5][6][7][8][9]. Therefore, modifying the surface with ideal coatings is of high significance for Mg alloy stents.…”
Constructing surface coatings is an effective way to improve the corrosion resistance and biocompatibility of magnesium alloy bioabsorbable implants. In this present work, a titanium oxide coating with a thickness of about 400 nm was successfully prepared on a MgZn alloy surface via a facile magnetron sputtering route. The surface features were characterized using scanning electron microscopy (SEM), atomic force microscopy (AFM), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and the contact angle method. The corrosion behavior and biocompatibility were evaluated. The results indicated that the amorphous TiO2 coating with a flat and dense morphology was obtained by magnetron-sputtering a titanium oxide target. The corrosion current density decreased from 1050 (bare MgZn alloy) to 49 μA/cm2 (sample with TiO2 coating), suggesting a significant increase in corrosion resistance. In addition, the TiO2 coating showed good biocompatibilities, including significant reduced hemolysis and platelet adhesion, and increased endothelial cell viability and adhesion.
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