Bioactive substances produced by marine isolates of Pseudomonas

Isnansetyo, Alim; Kamei, Yuto

doi:10.1007/s10295-009-0611-2

Cited by 74 publications

(50 citation statements)

References 78 publications

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“…Species from the Pseudomonas genus are the best studied of the Pseudomonadaceae family, whose sheer genetic diversity explains the ability to thrive in such a wide range of environments [99]. Marine isolates from the Pseudomonas genus have been shown to produce a wide range of bioactive compounds, many of which exhibit antibacterial as well as antiviral properties (see [100] for further references). Our results, indeed show an elevated level of Pseudomonadaceae OTUs evident on day 22 of the complete media cultures, and on days 8 and 22 of the minimal media cultures.…”

Section: Literature-based Assessment Of the Putative Role Of Each Bacmentioning

confidence: 99%

Dynamics of the Bacterial Community Associated with Phaeodactylum tricornutum Cultures

et al. 2017

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Abstract:The pennate diatom Phaeodactylum tricornutum is a model organism able to synthesize industrially-relevant molecules. Commercial-scale cultivation currently requires large monocultures, prone to bio-contamination. However, little is known about the identity of the invading organisms. To reduce the complexity of natural systems, we systematically investigated the microbiome of non-axenic P. tricornutum cultures from a culture collection in reproducible experiments. The results revealed a dynamic bacterial community that developed differently in "complete" and "minimal" media conditions. In complete media, we observed an accelerated "culture crash", indicating a more stable culture in minimal media. The identification of only four bacterial families as major players within the microbiome suggests specific roles depending on environmental conditions. From our results we propose a network of putative interactions between P. tricornutum and these main bacterial factions. We demonstrate that, even with rather sparse data, a mathematical model can be reconstructed that qualitatively reproduces the observed population dynamics, thus indicating that our hypotheses regarding the molecular interactions are in agreement with experimental data. Whereas the model in its current state is only qualitative, we argue that it serves as a starting point to develop quantitative and predictive mathematical models, which may guide experimental efforts to synthetically construct and monitor stable communities required for robust upscaling strategies.

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Section: Literature-based Assessment Of the Putative Role Of Each Bacmentioning

confidence: 99%

Dynamics of the Bacterial Community Associated with Phaeodactylum tricornutum Cultures

et al. 2017

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“…Several diketopiperazines (DKPs), uracil and 3-phenyl-2-propenoic acid produced by the deep sea bacterium Pseudomonas rhizosphaerae inhibited the growth of fouling bacteria (Qi, Xu, Gao et al 2009). Isnansetyo and Kamei (2009) reviewed several of the antibacterial substances from marine Pseudomonas species, including pyroles, quinoline and quinolone.…”

Section: Antibacterial Activity Heterotrophic Bacteriamentioning

confidence: 99%

Mini-review: Inhibition of biofouling by marine microorganisms

2013

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Any natural or artificial substratum exposed to seawater is quickly fouled by marine microorganisms and later by macrofouling species. Microfouling organisms on the surface of a substratum form heterogenic biofilms, which are composed of multiple species of heterotrophic bacteria, cyanobacteria, diatoms, protozoa and fungi. Biofilms on artificial structures create serious problems for industries worldwide, with effects including an increase in drag force and metal corrosion as well as a reduction in heat transfer efficiency. Additionally, microorganisms produce chemical compounds that may induce or inhibit settlement and growth of other fouling organisms. Since the last review by the first author on inhibition of biofouling by marine microbes in 2006, significant progress has been made in the field. Several antimicrobial, antialgal and antilarval compounds have been isolated from heterotrophic marine bacteria, cyanobacteria and fungi. Some of these compounds have multiple bioactivities. Microorganisms are able to disrupt biofilms by inhibition of bacterial signalling and production of enzymes that degrade bacterial signals and polymers. Epibiotic microorganisms associated with marine algae and invertebrates have a high antifouling (AF) potential, which can be used to solve biofouling problems in industry. However, more information about the production of AF compounds by marine microorganisms in situ and their mechanisms of action needs to be obtained. This review focuses on the AF activity of marine heterotrophic bacteria, cyanobacteria and fungi and covers publications from 2006 up to the end of 2012.

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“…Species from the Pseudomonas genus are the best studied of the Pseudomonadaceae family, whose sheer genetic diversity explains the ability to thrive in such a wide range of environments [69]. Marine isolates from the Pseudomonas genus have been shown to produce a wide range of bioactive compounds, many of which exhibit antibacterial as well as antiviral properties (see [70] for further references). Our results, indeed show an elevated level of Pseudomonadaceae OTUs evident on Day 22 of the complete media cultures, and on Days 8 and 22 of the minimal media cultures.…”

Section: Pseudomonadaceaementioning

confidence: 99%

Dynamics of the Bacterial Community Associated with <em>Phaeodactylum tricornutum</em> Cultures

Moejes¹,

Popa²,

Succurro³

et al. 2017

Preprint

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† These authors contributed equally to this work. Abstract:The pennate diatom Phaeodactylum tricornutum is a model organism able to synthesize industrially-relevant molecules. Commercial-scale cultivation currently requires large monocultures, prone to bio-contamination. However, little is known about the identity of the invading organisms. To reduce the complexity of natural systems, we systematically investigated the microbiome of non-axenic P. tricornutum cultures from a culture collection in reproducible experiments. The results revealed a dynamic bacterial community that developed differently in "complete" and "minimal" media conditions. In complete media, we observed an accelerated "culture crash", indicating a more stable culture in minimal media. The identification of only four bacterial families as major players within the microbiome suggests specific roles depending on environmental conditions. From our results we propose a network of putative interactions between P. tricornutum and these main bacterial factions. We demonstrate that, even with rather sparse data, a mathematical model can be reconstructed that qualitatively reproduces the observed population dynamics, thus indicating that our hypotheses regarding the molecular interactions are in agreement with experimental data. Whereas the model in its current state is only qualitative, we argue that it serves as a starting point to develop quantitative and predictive mathematical models, which may guide experimental efforts to synthetically construct and monitor stable communities required for robust upscaling strategies.

show abstract

Bioactive substances produced by marine isolates of Pseudomonas

Cited by 74 publications

References 78 publications

Dynamics of the Bacterial Community Associated with Phaeodactylum tricornutum Cultures

Dynamics of the Bacterial Community Associated with Phaeodactylum tricornutum Cultures

Mini-review: Inhibition of biofouling by marine microorganisms

Dynamics of the Bacterial Community Associated with <em>Phaeodactylum tricornutum</em> Cultures

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