Bioactive Restorative Dental Materials—The New Frontier

Melo, Mary Anne S.; Mokeem, Lamia; Sun, Jirun

doi:10.1016/j.cden.2022.05.005

Cited by 14 publications

(12 citation statements)

References 60 publications

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“…Future studies should compare the proposed restorative rapid-layer concept with novel strength-gradient multilayer zirconia SCs and FDPs. Other materials, such as bioactive restoratives, should also be explored as potential prosthetic materials [ 54 , 55 ]. Likewise, recently introduced two-piece ceramic implants with a screw-connection should be investigated in comparison to one-piece ceramic implants, as they allow increased prosthetic flexibility and retrievability of the suprastructure.…”

Section: Discussionmentioning

confidence: 99%

Failure Load and Fatigue Behavior of Monolithic and Bi-Layer Zirconia Fixed Dental Prostheses Bonded to One-Piece Zirconia Implants

et al. 2022

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No evidence-based prosthetic treatment concept for 3-unit fixed-dental-prostheses (FDPs) on ceramic implants is currently available. Therefore, the aim of this in vitro study was to investigate the failure load and fatigue behavior of monolithic and bi-layer zirconia FDPs supported by one-piece ceramic implants. Eighty 3-unit FDPs supported by 160 zirconia-implants (ceramic.implant; vitaclinical) were divided into 4 groups (n = 20 each): Group Z-HT: 3Y-TZP monolithic-zirconia (Vita-YZ-HT); Group Z-ST: 4Y-TZP monolithic-zirconia (Vita-YZ-ST); Group FL: 3Y-TZP zirconia (Vita-YZ-HT) with facial-veneer (Vita-VM9); Group RL (Rapid-layer): PICN “table-top” (Vita-Enamic), 3Y-TZP-framework (Vita-YZ-HT). Half of the test samples (n = 10/group) were fatigued in a mouth-motion chewing-simulator (F = 98 N, 1.2 million-cycles) with simultaneous thermocycling (5–55 °C). All specimens (fatigued and non-fatigued) were afterwards exposed to single-load-to-failure-testing (Z010, Zwick). Statistical analysis was performed using ANOVA, Tukey’s post-hoc tests and two-sample t-tests (p < 0.05, Bonferroni-corrected where appropriate). All specimens withstood fatigue application. While the effect of fatigue was not significant in any group (p = 0.714), the choice of material had a significant effect (p < 0.001). Material FL recorded the highest failure loads, followed by Z-ST, Z-HT and RL, both with and without fatigue application. Taken together, all tested FDP material combinations survived chewing forces that exceeded physiological levels. Bi-Layer FL and monolithic Z-ST showed the highest resilience and might serve as reliable prosthetic reconstruction concepts for 3-unit FDPs on ceramic implants.

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Section: Discussionmentioning

confidence: 99%

Failure Load and Fatigue Behavior of Monolithic and Bi-Layer Zirconia Fixed Dental Prostheses Bonded to One-Piece Zirconia Implants

et al. 2022

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“…In 2022, the FDI issued a Policy Statement on this topic highlighting general characteristics of bioactive materials, such as beneficial/desired effects from dental restorative materials and local effects comprising biological reactions, intentionality, and repair (Schmalz et al 2023). From a dental restorative perspective, "bioactivity" represents anticaries approaches at the material level, mostly involving modulation of the cariogenic biofilm, prevention of mineral loss, and the development of polymeric resistance to acidic, enzymatic, and bacterial decomposition (Melo et al 2022).…”

Section: Dental Resins-transition From Bioinert To Bioactivementioning

confidence: 99%

Developing Bioactive Dental Resins for Restorative Dentistry

et al. 2023

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Despite its reputation as the most widely used restorative dental material currently, resin-based materials have acknowledged shortcomings. As most systematic survival studies of resin composites and dental adhesives indicate, secondary caries is the foremost reason for resin-based restoration failure and life span reduction. In subjects with high caries risk, the microbial community dominated by acidogenic and acid-tolerant bacteria triggers acid-induced deterioration of the bonding interface and/or bulk material and mineral loss around the restorations. In addition, resin-based materials undergo biodegradation in the oral cavity. As a result, the past decades have seen exponential growth in developing restorative dental materials for antimicrobial applications addressing secondary caries prevention and progression. Currently, the main challenge of bioactive resin development is the identification of efficient and safe anticaries agents that are detrimental free to final material properties and show satisfactory long-term performance and favorable clinical translation. This review centers on the continuous efforts to formulate novel bioactive resins employing 1 or multiple agents to enhance the antibiofilm efficacy or achieve multiple functionalities, such as remineralization and antimicrobial activity antidegradation. We present a comprehensive synthesis of the constraints and challenges encountered in the formulation process, the clinical performance-related prerequisites, the materials’ intended applicability, and the current advancements in clinical implementation. Moreover, we identify crucial vulnerabilities that arise during the development of dental materials, including particle aggregation, alterations in color, susceptibility to hydrolysis, and loss of physicomechanical core properties of the targeted materials.

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“…135 There has been recent interest in materials with biofilm-inhibiting properties. 136,137 Two studies observed the effect of zinc-containing materials on the inhibition of Streptococcus mutans biofilm growth with encouraging results. 138,139 There has also been work on resin materials based on quaternary ammonium methacrylates in the hope that they might yield lasting antimicrobial effects.…”

Section: Smart Materials and Antimicrobial Materialsmentioning

confidence: 99%

“…There has been recent interest in materials with biofilm‐inhibiting properties 136, 137 . Two studies observed the effect of zinc‐containing materials on the inhibition of Streptococcus mutans biofilm growth with encouraging results 138, 139 .…”

Section: Orifice Barrier Materialsmentioning

confidence: 99%

Biological considerations of dental materials as orifice barriers for restoring root‐filled teeth

Wylie,

Parashos,

Fernando

et al. 2023

Australian Dental Journal

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There is ample published literature regarding the technical aspects of restoring root‐filled teeth, but little concerning the biological impacts, consequences, and criteria for the selection of direct restorative materials following endodontic treatment. The provision of an effective coronal seal in addition to a sound root filling is known to be important in the prevention of root canal infection. This review seeks to explore the evidence concerning the selection of dental materials in the restoration of root‐filled teeth, specifically with a close examination of the properties of commonly used materials as orifice barriers. © 2023 Australian Dental Association.

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Bioactive Restorative Dental Materials—The New Frontier

Cited by 14 publications

References 60 publications

Failure Load and Fatigue Behavior of Monolithic and Bi-Layer Zirconia Fixed Dental Prostheses Bonded to One-Piece Zirconia Implants

Failure Load and Fatigue Behavior of Monolithic and Bi-Layer Zirconia Fixed Dental Prostheses Bonded to One-Piece Zirconia Implants

Developing Bioactive Dental Resins for Restorative Dentistry

Biological considerations of dental materials as orifice barriers for restoring root‐filled teeth

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