Bioactive properties of powdered peppermint and spearmint extracts: Inhibition of key enzymes linked to hypertension and type 2 diabetes

Çam, Mustafa; Başyi̇ği̇t, Bülent; Alaşalvar, Hamza; Yılmaztekin, Murat; Ahhmed, Abdulatef M.; Sağdıç, Osman; Konca, Yusuf; Telci, İ̇sa

doi:10.1016/j.fbio.2020.100577

Cited by 24 publications

(14 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Therefore, the high ME could be due to the coating material (maltodextrin) rather than the inlet air temperature. Maltodextrin is a suitable coating material to carry out a successful encapsulation of phenolics (Cam et al., 2020). An increase in dry matter content and a decrease in water activity were observed with an increase in inlet air temperature.…”

Section: Resultsmentioning

confidence: 99%

“…Dry matter content, water activity, solubility, color, bulk, and tapped density, and Carr's index were measured as described by Cam et al. (2020).…”

Section: Methodsmentioning

confidence: 99%

“…The absorbance was measured at 515 nm (Brand‐Williams et al., 1995). DPPH radical scavenging activity (as EC 50 values), the amount of sample necessary to decrease initial DPPH concentration by 50%, was calculated and expressed as g sample per g DPPH according to Cam et al (2020).…”

Section: Methodsmentioning

confidence: 99%

See 2 more Smart Citations

Extraction optimization and microencapsulation of phenolic antioxidant compounds from lemon balm ( Melissa officinalis L.): Instant soluble tea production

Tülek

Alaşalvar

Başyi̇ği̇t

et al. 2020

J Food Process Preserv

Self Cite

View full text Add to dashboard Cite

The purpose of this study was to extract phenolics from lemon balm followed by microencapsulation with spray drying. The optimum extraction conditions were 100°C for the temperature and 120 min for the time with TPC of 6,365 mg GAE/100 g and ABTS radical scavenging activity of 9,196 mg TEAC/100 g. Lemon balm extracts were spray dried using three different air inlet temperatures (130°C, 165°C, and 200°C) of which 165°C was provided better scores than the other points in terms of microencapsulation yield (65.9%), microencapsulation efficiency (99.4%), dry matter (98.3%), and water activity (0.160). The inlet air temperatures had an insignificant (p > .05) effect on the antioxidant capacity of the microcapsules. Phenolic acids in lemon balm were slightly affected by the extraction and spray drying conditions. However, extraction followed by spray drying resulted in significant loss in the amount of volatiles such as geranial, neral, citronellal, and caryophyllene. Practical applications Hot water extracts of the medicinal and aromatic plants are consumed as herbal tea across the world and their biological activity varies depending on the extraction conditions. Furthermore, bioactive compounds are sensitive to environmental conditions when the compounds dissolved in water. The conditions necessary for the effective extraction of bioactive compounds are specific to the target plant and it is a problem for the consumer. Optimization of extraction conditions of lemon balm phenolics could provide useful information for the consumer and food industry. The production of phenolic microcapsules (instant soluble tea) from lemon balm could facilitate herbal tea preparation and reduce the preparation time.

show abstract

Section: Resultsmentioning

confidence: 99%

“…Dry matter content, water activity, solubility, color, bulk, and tapped density, and Carr's index were measured as described by Cam et al. (2020).…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Extraction optimization and microencapsulation of phenolic antioxidant compounds from lemon balm ( Melissa officinalis L.): Instant soluble tea production

Tülek

Alaşalvar

Başyi̇ği̇t

et al. 2020

J Food Process Preserv

Self Cite

View full text Add to dashboard Cite

show abstract

“…The potent inhibitory effect of the α-amylase may be in uenced by the abundance of phenolic compounds in MEAE. It has been reported in the literature that Ephedra alata alcohol extract contain bioactive principle that may be useful in the management or prevention of diabetic complications [29,30]. In fact, The LC-DAD-ESI/MSn pro le of E. alata was characterized by the presence of various phenolic compounds, all belonging to avonoids class, namely ve iso avones the diazein, the Epicatechin, the rutin as well as the quercitin and avones;…”

Section: Discussionmentioning

confidence: 99%

Ephedra alata extracts exhibits anti-obesity, anti-hyperlipidaemic, anti-hyperglycemia, anti-antipyretic and analgesic effects through the inhibition of lipase, α-amylase and inflammation

Tiss¹,

Souiy²,

Boujbiha³

et al. 2020

Preprint

View full text Add to dashboard Cite

In this present study, phytochemical screening, anti-obesity, anti- antipyretic and analgesic effect of Ephedra alata (EA) extracts were evaluated. Results of this study showed that the methanol EA extract (MEAE) had a stronger inhibition activity on key enzyme related to obesity as lipase (IC50 = 1.296 mg/ml) as compared to water and ethyl acetate extracts ( with IC50 = 1.639 and 1.897 respectively). Also results revealed that ethyl acetate extract depicted high activity toward key enzyme related to hyperglycemia as α-amylase (IC50 = 0.284 mg/mL) while water and methanol extracts showed good to moderate inhibitory activity (IC50 = 1,525 and 1,103 mg/ml respectively). In HFFD rats, the administration of MEAE at 200 mg/kg inhibited key enzyme related to fat digestion and absorption as lipase in the intestine, pancreas and serum by 53, 40 and 53% respectively,which leads to decrease in body weight by 20% and also modulation of lipid profile. In addition, the administration of MEAE to HFFD-rats exerts an inhibitory effect on α-amylase activity in the intestine, pancreas and serum by 43, 26 and 46% respectively and this leads to decrease in blood glucose level by 35%. Also, MEAE exert antipyretic and analgesic activities. This study demonstrates for the first time that MEAE are efficient in preventing obesity and hyperglycemia and liver toxicity. This data generated during study shows antipyretic and analgesic activities of MEAE.

show abstract

“…Both mint species are a source of bioactive compounds, rich in antioxidants, phenolics, and other phytonutrients. Due to their health benefits, these species are also classified as medicinal crops [2,3]. However, the active constituents of medicinal plants such as spearmint and peppermint are used in clinical studies and new drug development, but their restricted intensive cultivation sets limitations in the production of medicines [4].…”

Section: Introductionmentioning

confidence: 99%

Responses of Peppermint and Spearmint Crops to Excessive Biostimulant Application and Increased Salinity in a Closed Soilless Production System

et al. 2021

View full text Add to dashboard Cite

A floating system was established in a heated glass greenhouse in order to investigate whether the effect of amino acids (0.25 or 0.50% of a commercial amino acid (AA) solution Amino16®) during peppermint and spearmint production on plant developmental and nutritional status may be in part attributed to salinity induced osmotic stress. For this reason, in some nutrient solutions, three levels of salinity were induced by adding 0, 10, or 20 mM NaCl. According to the results, it can be concluded that spearmint is mostly favored by the highest amino acid supplement of the nutrient solution (0.50%) in terms of a substantial improvement of the antioxidant nutritional quality (by up to 130%) at the expense of a reduced biomass production (by <30%). Enzymic antioxidant defense mechanism (APX and POD) was efficiently activated, preventing severe lipid peroxidation and the accumulation of reactive oxygen species such as H2O2 and maintaining the proline content at the normal levels. The osmotic stress that was induced by the excessive AA concentration and confirmed by the chlorophyl fluorescence variations was probably related to NH4+ excess supply in the growing media and was not associated with the elevated electrical conductivity in the solution. The absence of any adverse stressful consequences upon the addition of 20 mM NaCl may be attributed to the high salt tolerance of peppermint and spearmint species.

show abstract

Bioactive properties of powdered peppermint and spearmint extracts: Inhibition of key enzymes linked to hypertension and type 2 diabetes

Cited by 24 publications

References 44 publications

Extraction optimization and microencapsulation of phenolic antioxidant compounds from lemon balm ( Melissa officinalis L.): Instant soluble tea production

Extraction optimization and microencapsulation of phenolic antioxidant compounds from lemon balm ( Melissa officinalis L.): Instant soluble tea production

Ephedra alata extracts exhibits anti-obesity, anti-hyperlipidaemic, anti-hyperglycemia, anti-antipyretic and analgesic effects through the inhibition of lipase, α-amylase and inflammation

Responses of Peppermint and Spearmint Crops to Excessive Biostimulant Application and Increased Salinity in a Closed Soilless Production System

Contact Info

Product

Resources

About