Bioactive monoterpene glycosides conjugated with gallic acid from the leaves of Eucalyptus globulus

Hasegawa, Tatsuya; Takano, Fumihide; Takata, Takanobu; Niiyama, Masato; Ohta, Tomihisa

doi:10.1016/j.phytochem.2007.08.030

Cited by 100 publications

(81 citation statements)

References 22 publications

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“…E. globulus is one of the most interesting species among the more than 600 species comprising the genus Eucalyptus (Hasegawa et al, 2008). In Brazil this genus also has a great therapeutical importance and several species of Eucalyptus are used in traditional medicine as antiseptics, and against infections of the upper respiratory tract, such as the common cold, influenza and sinus congestion; besides this exhibit antibacterial, analgesic and anti-inflammatory activities (Silva et al, 2003).…”

Section: Few Ethnopharmacological Surveys Amongmentioning

confidence: 99%

Essential oils found in the smoke of "tira-capeta", a cigarette used by some quilombolas living in pantanal wetlands of Brazil

Negri¹,

Rodrigues²

2010

Rev. bras. farmacogn.

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RESUMO: "Óleos essenciais encontrados na fumaça do ¨tira-capeta¨, um cigarro utilizado pelos quilombolas que vivem no pantanal do Brasil". Pesquisa etnofarmacológica realizada entre os quilombolas que vivem na Sesmaria Mata-Cavalos, no Estado de Mato Grosso, Brasil, um cigarro conhecido como ¨tira-capeta¨, foi citado por melhorar a memória e cognição, além de possuir outras indicações terapêuticas, tais como, "contra a sinusite", "para evitar resfriado", e "para aliviar problemas de insônia". No presente estudo, foi feita a caracterização dos óleos essenciais liberados durante o aquecimento das plantas utilizadas na confecção do cigarro, usando um método simples, rápido e livre de solvente baseado em cromatografia gasosa acoplada a espectrometria de massas usando "headspace" e microextração em fase sólida. Os principais constituintes encontrados foram 1,8-cineol, cânfora e α-pineno. Na tentativa de correlacionar a atividade biológica desses constituintes com as indicações terapêuticas relatadas pelos quilombolas, encontramos vários trabalhos realizados por diversos autores que mostraram que estes óleos possuem atividades similares às indicações terapêuticas relatadas pelos quilombolas.Unitermos: Etnofarmacologia, óleos essenciais, medicina popular, sistema nervoso central, quilombolas, memória. ABSTRACT: An ethnopharmacological survey developed among quilombolas living in SesmariaMata-Cavalos, in the State of Mato Grosso, Brazil; a cigarette known as "tira-capeta" (removingthe-devil), had been cited mainly "to improve memory and cognition", and also showed other therapeutical indications, such as: "against sinusitis", "to avoid cold", "to relieve sleep problems". The purpose of the present study was carried out a screening of essential oils delivered in the heating of plants used to produce the "tira-capeta" cigarette, using a simple, rapid and solvent-free method based on gas chromatography-mass spectrometry and headspace solid-phase microextraction. The principal essential oils found were 1,8 cineole, camphor and α-pinene. In the tentative to correlate these constituents with therapeutical indications reported by the quilombolas, were found some works carried out by many authors that corroborated the therapeutical indications reported by the quilombolas.

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Section: Few Ethnopharmacological Surveys Amongmentioning

confidence: 99%

Essential oils found in the smoke of "tira-capeta", a cigarette used by some quilombolas living in pantanal wetlands of Brazil

Negri¹,

Rodrigues²

2010

Rev. bras. farmacogn.

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“…Vet. Eucalyptus citriodora (Myrtaceae) is a plant native to Australia, and is widely cultivated around the world. It is the most common species used in Brazil for extraction of essential oil (HASEGAWA et al, 2008). It is used in anti-inflammatory and antipyretic remedies for the symptoms of respiratory infections, such as colds, flu and sinus congestion (SILVA et al, 2003).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Eucalyptus citriodora essential oil on goat gastrointestinal nematodes

Macedo

Beviláqua

Oliveira

et al. 2011

Rev. Bras. Parasitol. Vet.

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Phytotherapy may be an alternative strategy for controlling gastrointestinal parasites. This study evaluated the anthelmintic efficacy of Eucalyptus citriodora essential oil (EcEO). The in vitro effects of EcEO were determined through testing the inhibition of egg hatching and larval development of Haemonchus contortus. EcEO was subjected to acute toxicity testing on mice, orally and intraperitoneally. The in vivo effects of EcEO were determined by the fecal egg count reduction test (FECRT)

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“…Eucalyptus spp. (Myrtaceae) is native to Australia and is mainly cultivated for use by the paper, pharmaceutical and cosmetic industries (Hasegawa et al 2008). The nematicide action of Eucalyptus staigeriana essential oils (EsEO) was described previously (Macedo et al 2010, Mesquita et al 2013.…”

Section: Introductionmentioning

confidence: 99%

The use of Eucalyptus staigeriana nanoemulsion for control of sheep haemonchosis

et al. 2017

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Sustainable control of gastrointestinal nematodes (GIN) in small ruminants has been based on the use of alternative methods, including targeted selective treatment, such as FAMACHA. Another GIN control alternative is the use of herbal medicines, although in many cases their use is based on empirical knowledge. Biopolymer nanoformulations has been investigated to maximize the essential oil effects against sheep gastrointestinal nematodes. The aim of the present study was to combine a Eucalyptus staigeriana essential oil nanoemulsion (EsNano) with FAMACHA as an alternative control for sheep haemonchosis. The study was performed over six months at a commercial sheep farm located in a semiarid region of Northeast Brazil. Initially, a fecal egg count reduction test (FECRT) in sheep with levamisole, ivermectin and oxfendazole in sheep was performed used to determine the most effective anthelmintic to use as the positive control. Levamisole has been selected because it showed efficacy superior to 95%. EsNano was obtained and then its physicochemical properties were characterized. The average (±SE) size of the particles in the nanoemulsion was 276.8 (±12.3) nm with bimodal distribution and polydispersity. Nine visits were performed, from April to September 2013, with an interval of 17 days. One hundred sixty-two male and female sheep were divided into three groups (n=54 each) and were treated when FAMACHA score was 3, 4, or 5: G-EsNano 250mg kg -1 EsNano; G-Lev 7.5mg kg -1 levamisole (positive control), and G-Neg was not treated (negative control). Feces from sheep were collected to quantify the number of eggs per gram of feces (epg) and to identify nematode genera. Sheep weight gain was monitored. The epg data for each group and the average sheep weight gains were analyzed by variance analysis and compared with the Tukey's test (P<0.05). Significant difference between the number of animals treated with EsNano and levamisole was not observed in any visit (P>0.05). The epg variation was similar in the G-EsNano and G-Lev groups on visits (P>0.05), except the second and fifth evaluation in the epg groups were significantly different (P<0.05). Haemonchus spp. was the most prevalent nematode. There was no significant weight gain in any of the treated groups (P<0.05). The combination of phytotherapy and FAMACHA can be an alternative to minimize the use of synthetic anthelmintics to control resistant GIN populations of small ruminants.

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Bioactive monoterpene glycosides conjugated with gallic acid from the leaves of Eucalyptus globulus

Cited by 100 publications

References 22 publications

Essential oils found in the smoke of "tira-capeta", a cigarette used by some quilombolas living in pantanal wetlands of Brazil

Essential oils found in the smoke of "tira-capeta", a cigarette used by some quilombolas living in pantanal wetlands of Brazil

Evaluation of Eucalyptus citriodora essential oil on goat gastrointestinal nematodes

The use of Eucalyptus staigeriana nanoemulsion for control of sheep haemonchosis

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