Bioactive Lipids

Aluko, Rotimi E.

doi:10.1007/978-1-4614-3480-1_2

Cited by 11 publications

(1 citation statement)

References 21 publications

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“…Although the primary function of bioactive fatty acids is as an energy source, they also play an important role in human health, namely in cell structure and signalling [1,2]. Moreover, they help maintain homeostasis and prevent metabolic disorders, and some fatty acids are essential as precursors in the production of hormones and vitamins [1][2][3][4]. The more well-established health effects of bioactive fatty acids are related to cardiovascular disease.…”

Section: Introductionmentioning

confidence: 99%

Does the Nature of Added Bioactive Lipids Affect the Biological Properties of Yogurts?—Case Study Coconut and Avocado Oils

et al. 2023

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Bioactive lipids play an important role in human health and their benefits are linked to their chemical nature; for example, medium-chain fatty acids can have an important contribution to body weight management. This work aimed to test a strategy to enhance the quality profile and gastrointestinal tract resistance of previously developed vegetable oil-functionalized yogurts and further probe the biological potential of functionalized yogurts. Fortification with coconut and avocado vegetable oils led to increased nutritional value through an increase in essential fatty acids content, particularly in yogurts with vegetable oil bigels. One of the main problems with bioactive fatty acids fortification is their poor stability during in vitro digestion and consequently poor bioavailability. Despite this, the digested samples decreased lipid accumulation in Hep G2 and 3T3-L1 cells Functionalized yogurts were also responsible for high improvements in adiponectin secretion (35% for COY, 46% for CBY, 53% for AOY, and 48% ABY) compared with control yogurt. Moreover, in the inflammatory model, a reduction between 30% (for control yogurt) and 70% (for CBY) was observed for IL-6 secretion in LPS-stimulated cells. Considering these results, yogurt’s fortification with vegetable oils can be a viable alternative strategy to be scaled up for obesity management.

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