2016
DOI: 10.1016/j.phytochem.2016.05.014
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Bioactive ent-kaurane diterpenoids from Isodon serra

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Cited by 23 publications
(16 citation statements)
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“…Se ha informado que estos diterpenoides contribuyen al proceso antiinflamatorio activando fagocitos, que están relacionados con la defensa celular. Además, se informó una reducción del daño hepático en ratas con una dieta rica en compuestos diterpénicos (Wan et al, 2016). Kauran-15-ol y kauran-16-ol, son parte de la síntesis de giberelinas y están asociados con la etapa de formación de semillas en frutos (Pearce et al, 1994).…”
Section: Cromatografía De Gases/ Espectrometría De Masasunclassified
“…Se ha informado que estos diterpenoides contribuyen al proceso antiinflamatorio activando fagocitos, que están relacionados con la defensa celular. Además, se informó una reducción del daño hepático en ratas con una dieta rica en compuestos diterpénicos (Wan et al, 2016). Kauran-15-ol y kauran-16-ol, son parte de la síntesis de giberelinas y están asociados con la etapa de formación de semillas en frutos (Pearce et al, 1994).…”
Section: Cromatografía De Gases/ Espectrometría De Masasunclassified
“…The 13 C NMR spectrum ( Table 2 ), associated with HSQC experiment, exhibited 20 carbon resonances attributed to two methyls, nine methylenes [including one oxygenated carbon at δ C 66.6 (C-20) and one olefinic carbon at δ C 113.9 (C-17)], three methines, and six quaternary carbons [including one ketal carbon at δ C 96.1 (C-7), one olefinic carbon at δ C 155.4 (C-16), and one carbonyl carbon at δ C 204.9 (C-15)]. Analysis of the 1 H and 13 C NMR spectroscopic data of compound 3 showed a structure related to the known compound serrin E (a 7,20-epoxy- ent -kaurane diterpenoid) ( Wan et al, 2016 ), except for one oxygenated methine in serrin E that was replaced by a methylene in 3 at C-1 position. The planar structure of 3 was confirmed by the 1 H- 1 H COSY correlations of H 2 -1/H 2 -2/H 2 -3 and the HMBC correlations from H 2 -1 to C-2, C-5, C-9, and C-10, and from H 2 -20 to C-1 ( Figure 2 ).…”
Section: Resultsmentioning
confidence: 98%
“…The total absence of labeled botanical ingredients and/or their extracts from the commercial herbal products tested was detected by using chemical methods. Commercial samples devoid of labeled botanical ingredient species (Carlson and Thompson, 1998;Ardila et al, 2015;Geng et al, 2019;Zhu et al, 2019) or not even substituted with their related species (Wan et al, 2016). An easy way to increase the profit margin of the products was the use of cheaper plant material as it was the use of other plant parts than the ones recommended, labeled and expected by the product's users, senna (Senna alexandrina Mill.)…”
Section: Discussionmentioning
confidence: 99%