Bioactive core material for porous load-bearing implants

Abstract

So far state of knowledge on biodegradable materials is reviewed. Among a variety of investigated materials, those composed of polymers and ceramics may be considered as only candidates for a core material in porous titanium alloy. The collagen and chitosan among natural polymers, polyhydroxy acids among synthetic polymers, and hydroxyapatite and tricalcium phosphate among ceramics are proposed for further research. Three essential conditions for a core material are defined as: biodegradation rate "in vitro" and "in vivo" close to bone tissue in-growth rate, high compression strength and ability to form nanoporous open structure inside the material for vascularisation. Possible deposition techniques of a core material within the macropores of metallic scaffold include infiltration of titanium porous structure with polymer scaffold followed by precipitation of phosphate nanoparticles, and mixing of phosphate and polymers before deposition followed by controlled precipitation inside the pores.

Spectroscopic Characterization of Copper-Chitosan Nanoantimicrobials Prepared by Laser Ablation Synthesis in Aqueous Solutions

“…Noteworthy, CS can efficiently chelate and/or coordinate metals, ensuring the possibility to prepare metal-containing coordination polymers and composites [ 23 ]. In particular, metal-chitosan (Me-CS) composites have many fascinating applications in catalysis, biosensors and biomaterials [ 24 , 25 ]. A number of studies have been issued on CS combination with different inorganic nanostructures, such as Pd [ 26 , 27 ], Au [ 28 , 29 , 30 , 31 , 32 ], Ag and its compounds [ 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 ], Pt [ 27 , 41 ], Fe and its oxides [ 42 , 43 , 44 ], ZnO [ 20 , 45 , 46 ], zeolite [ 47 ], silica [ 48 ] and graphene [ 49 ], just to cite a few.…”

Regularities of Adsorption of Α-Oxypropionic Acid By Natural Zeolite

“…In fact, the production of polylactide will allow to obtain polymeric materials capable to biological destruction [21,22]. Currently, polylactide is synthesized by homogeneous catalysis, which has certain disadvantages [23,24]. It is also known that the adsorption of most compounds is not affected by the high acidity of the solutions [7,8].…”