Bioactive Compounds from Tree Endophytes

First Report: Diversity of Endophytic fungi Possessing Antifungal Activity Isolated from Native Kougoed (Sceletium tortuosum L.)

“…Novel biotechnological approaches that focuses on the utilization of bioactive compounds isolated from endophytes for a broad spectrum of biological potentials, including antibiotics, antiviral, immunosuppressant, antiparasitic, and antifungal activities, have sparked tremendous interest in recent research [1]. Historically, ground breaking bioactive compounds isolated from endophytic fungi have been commercialized as pharmaceutical drugs from penicillin, camptothecin, podophyllotoxin to taxol [2]. Endophytic fungi live inside a plant tissue with no harmful symptoms observed.…”

“…In this study, we established that endophytic fungi isolated from medicinal plant of South Africa possess excellent antifungal properties against pathogenic fungi. Endophytic fungi are untapped territories filled with effective, novel bioactive compounds [2] to control fungal pathogens responsible for the mortality rate and high crop losses (Figure 2). In conclusion, these endophytic fungi have potential to be used as a natural biocontrol agent in the agricultural sector; antifungal agents in the medical as well Table 2.…”