Bioactive compounds from date fruit and seed as potential nutraceutical and functional food ingredients

Maqsood, Sajid; Adiamo, Oladipupo Q.; Ahmad, Mudasir; Mudgil, Priti

doi:10.1016/j.foodchem.2019.125522

Cited by 220 publications

(185 citation statements)

References 93 publications

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“…Currently, the agroforestry by-products have been increasingly exploited to isolate biocompounds with high industrial interest. Studies using natural matrices as a potential source of bioactive compounds have been published in recent decades [7,[62][63][64][65][66][67]. For instance, in a new review paper [68], the authors report that in addition to fruits and vegetables, tree barks are rich in phenolic compounds with excellent biological properties (such as antioxidant, immunostimulatory, anticancer, antibacterial, anti-inflammatory, antimutagenic, etc.)…”

Section: Pine Applicationsmentioning

confidence: 99%

Green and Sustainable Valorization of Bioactive Phenolic Compounds from Pinus By-Products

et al. 2020

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In Europe, pine forests are one of the most extended forests formations, making pine residues and by-products an important source of compounds with high industrial interest as well as for bioenergy production. Moreover, the valorization of lumber industry residues is desirable from a circular economy perspective. Different extraction methods and solvents have been used, resulting in extracts with different constituents and consequently with different bioactivities. Recently, emerging and green technologies as ultrasounds, microwaves, supercritical fluids, pressurized liquids, and electric fields have appeared as promising tools for bioactive compounds extraction in alignment with the Green Chemistry principles. Pine extracts have attracted the researchers’ attention because of the positive bioproperties, such as anti-inflammatory, antimicrobial, anti-neurodegenerative, antitumoral, cardioprotective, etc., and potential industrial applications as functional foods, food additives as preservatives, nutraceuticals, pharmaceuticals, and cosmetics. Phenolic compounds are responsible for many of these bioactivities. However, there is not much information in the literature about the individual phenolic compounds of extracts from the pine species. The present review is about the reutilization of residues and by-products from the pine species, using ecofriendly technologies to obtain added-value bioactive compounds for industrial applications.

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Section: Pine Applicationsmentioning

confidence: 99%

Green and Sustainable Valorization of Bioactive Phenolic Compounds from Pinus By-Products

et al. 2020

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“…Among the most prominent activities of phenolic compounds are the activity of free radicals' inhibition, antibacterial, anticancer, etc., and more recently the activity of inhibiting digestive enzymes, such as α-amylase and α-glycosidase, involved in the pathological state of hyperglycemia associated with diabetes mellitus. Inhibition of these enzymes blocks carbohydrate hydrolysis and decreases glucose absorption in the body [4,22,48,49].…”

Section: Antihyperglycemic Activitymentioning

confidence: 99%

Unravelling the Biological Potential of Pinus pinaster Bark Extracts

et al. 2020

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Natural compounds from agro-food by-products have fostered interest in food industries. The aim of this study was to unravel potential uses for Pinus pinaster bark extracts (PBE). As functional features of this type of extracts are usually attributed to phenolic compounds, the extraction process was studied. Different PBEs were achieved, with high content in phenolic compounds, using different water/ethanol combinations as a solvent. These PBEs were chemically characterized, and their bioactivity and in vitro cell viability were evaluated. Extracts obtained with hydroethanolic solvents had higher content in phenolic and flavonoid compounds. All the PBEs presented high antioxidant, antibacterial and antihyperglycemic activities. Moreover, PBEs have low cytotoxicity and a selective activity against cancer cells as these were negatively affected. These features may allow the extracts to be used in food formulation and processing (as preservatives, antioxidants or bioactive ingredients), but they showed also potential for the pharmaceutical or nutraceutical sectors.

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“…Dates have several other medicinal health benefits because of their functional compounds. Dates are anti‐ulcerative, nephroprotective, hepatoprotective, spermatogenic, and antiviral (Maqsood, Adiamo, Ahmad, & Mudgil, 2019). In Turkey, a herbal coffee named as “Hurma coffee” which is obtained from date seed is being consumed for the purpose of improving memory (Sekeroglu et al., 2012).…”

Section: Biological and Therapeutic Potential Of Datesmentioning

confidence: 99%

Functional food and nutra‐pharmaceutical perspectives of date ( Phoenix dactylifera L.) fruit

et al. 2020

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Date palm counts among the oldest fruit crops of the world and is mainly cultivated for its highly nutritious fruits consumed as a staple food in many countries, especially in the Gulf region. Dates are enriched with numerous therapeutic bioactives and functional compounds such as phenolics, flavonols, carotenoids, minerals, and vitamins that not only provide an appreciable amount of energy required for the human body but also act as an effective therapeutic agent against several diseases. This review aimed to provide a deep insight into the nutritional as well as phytochemicals profile of date fruit and its seeds in order to explore their biological (anti‐cancer, anti‐diabetic, cardio‐protective, anti‐inflammatory properties), functional food, and nutra‐pharmaceutical attributes. Practical applications This review provides updated information regarding the date fruits and seeds phytochemicals composition together with highlighting dates potential as a natural therapeutic agent against several diseases. The study also urges the importance of consuming dates as a great package to live a healthy life due to the functional food and nutraceutical properties of this valuable fruit. The study also provides information first time as recommending dates to cope with the hidden hunger or micronutrient deficiency faced by the third world inhabitants. Hence, the review may further help the industry and researchers to explore the potential of dates for future medicinal and nutra‐pharmaceutical applications.

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Bioactive compounds from date fruit and seed as potential nutraceutical and functional food ingredients

Cited by 220 publications

References 93 publications

Green and Sustainable Valorization of Bioactive Phenolic Compounds from Pinus By-Products

Green and Sustainable Valorization of Bioactive Phenolic Compounds from Pinus By-Products

Unravelling the Biological Potential of Pinus pinaster Bark Extracts

Functional food and nutra‐pharmaceutical perspectives of date ( Phoenix dactylifera L.) fruit

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