Bioactive composition and antibacterial activity of three herbal extracts (lemongrass, sage, and guava leaf) against oral bacteria: An in vitro study

Elchaghaby, Marwa A.; El-Kader, Shereen Farouk Abd; Aly, Mariam Mohsen

doi:10.1016/j.job.2022.01.005

Cited by 13 publications

(4 citation statements)

References 27 publications

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“…Os primeiros estudos de óleos voláteis nas folhas examinaram as concentrações de terpeno nos óleos essenciais para fins de quimiotaxonomia (201). Dentre os mono-e sesquiterpenos já identificados no óleo essencial das folhas da espécie, estão 8-cineol, limoneno, α-pineno (monoterpenos), cariofileno, α-cedreno, β-bisaboleno, aroma-dendreno, β-selineno, nerolidol e óxido de cariofileno (sesquiterpenos) (2,3,(201)(202)(203)(204)(205)(206). Estudos confirmaram a presença de β-cariofileno, α-pineno e 1,8-cineol como compostos principais no óleo essencial das folhas (207).…”

Section: Droga Vegetal (Folhas)unclassified

Etnofarmacologia, Fitoquímica, Toxicologia E Atividades Anti-Inflamatória E Antinociceptiva De Folhas De Psidium Guajava L.: Uma Revisão

Almeida,

Martins,

Souza

et al. 2023

Infarma

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Psidium guajavaL. (Myrtaceae), conhecida como goiabeira, é uma importante espécie vegetal com diversos valores medicinais. Na medicina tradicional, é utilizada para o tratamento de uma série de doenças, como distúrbios gastrointestinais, processos inflamatórios, no tratamento de cáries, em afecções dermatomucosas, como analgésico, em distúrbios respiratórios, dentre outros. As ações podem ser atribuídas à infinidade de compostos bioativos presentes em P. guajava. O objetivo desta revisão é fornecer informações atualizadas sobre os usos etnomedicinais, compostos bioativos, potenciais ações anti-inflamatória e antinociceptiva, além da toxicidade das folhas de P. guajava L. A estratégia de busca utilizada continha o nome científico, sinonímias e nomes populares da espécie vegetal. As bases de dados consultadas foram Cochrane, Medline, SCOPUS, Science Direct, Web of Science, Lilacs, SciELO, Google acadêmico e Google books.; além de monografias em compêndios oficiais. Dentre os principais fitoquímicos extraídos de folhas de P. guajava, podem ser citados compostos dos grupos dos flavonoides, taninos, terpenoides, saponinas e óleos essenciais. Estudos in vitro e in vivo sugerem que derivados das folhas da espécie vegetal possuem potencial anti-inflamatório e antinociceptivo. Assim, considerando seu perfil fitoquímico e seus efeitos benéficos, derivados das folhas da espécie podem, potencialmente, serem utilizados no desenvolvimento de produtos farmacêuticos. Contudo, lacunas consideráveis ainda precisam ser preenchidas, como por exemplo, aquelas relacionadas a padronização do método extrativo e no que diz respeito a relação droga:derivado obtida. Ademais, há necessidade de ensaios clínicos mais robustos para estabelecer as doses seguras e a eficácia de P. guajava como agente anti-inflamatório.

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Section: Droga Vegetal (Folhas)unclassified

Etnofarmacologia, Fitoquímica, Toxicologia E Atividades Anti-Inflamatória E Antinociceptiva De Folhas De Psidium Guajava L.: Uma Revisão

Almeida,

Martins,

Souza

et al. 2023

Infarma

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“…7 Modern pharmacological research has demonstrated that guava leaves have antioxidant, antiviral, and antibacterial activities. 8 Previous research demonstrated that guava-leaf extract can improve the immunity of Labeo rohita. 9 Moreover, guava also greatly reduced the mortality rate of Oreochromis mossambicus and increased its resistance to Aeromonas hydrophila.…”

Section: First Authormentioning

confidence: 99%

Effects of dietary guava leaf aqueous extract supplementation on growth, antioxidant capacity, and non-specific immunity in mud crab Scylla paramamosain

Yan

Cheng

et al. 2023

Israeli Journal of Aquaculture - Bamidgeh

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Mud crab (Scylla paramamosain) fed five different diets with varying concentrations of guava leaf aqueous extract (0 mg·kg–1, 80 mg·kg–1, 160 mg·kg–1, 320 mg·kg–1, and 640 mg·kg–1) for 30 days. Mud crabs in the 320 mg·kg–1 guava-leaf extract groups outperformed the control group in terms of survival rates (SR), weight gain rates (WGR), and specific growth rates (SGR). When compared to the control group, mud crabs in the 320 mg·kg–1 guava-leaf extract groups had significantly higher levels of lipase (LPS), pepsin, lysozyme (LZM), superoxide dismutase (SOD), acid phosphatase (ACP), and glutathione (GSH) (P < 0.05). The amylase (AMS) activity was significantly decreased in all experimental groups (P < 0.05). Malondialdehyde (MDA) content in the hepatopancreas of mud crabs in the 160 mg·kg–1, 320 mg·kg–1, and 640 mg·kg–1 guava-leaf extract groups were significantly reduced compared to the control group (P < 0.05). Additionally, real-time PCR results illustrated that the expression levels of GPx3, CAT, and JNK were all considerably increased in the 80 mg·kg–1 guava-leaf extract groups compared to the control group (P < 0.05). In the 160 mg·kg–1, 320 mg·kg–1, and 320 mg·kg–1 guava-leaf extract groups, the expression levels of SOD genes were considerably greater than the control (P < 0.05), which was consistent with the level of SOD activity. GST and P53 gene expression levels were significantly up-regulated in the 80 mg·kg–1, 160 mg·kg–1, 320 mg·kg–1, and 640 mg·kg–1 guava-leaf extract groups compared to the control group (P < 0.05). Overall, the addition of 160 mg·kg–1-320 mg·kg–1 guava-leaf extract to the feed of Scylla paramamosain promoted growth, enhanced the activities of digestive and antioxidant enzymes, and strengthened immunity.

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“…8,9 Plant extracts can serve as cost-effective and environmentally sustainable prophylactic or antimicrobial agents. Guava (Psidium guajava) leaf (GLE) are rich in various phenolic and flavonoid compounds 10 and possess antimicrobial, 11 antiviral, 12 and antioxidant 13 activities. GLE have been employed as supplements in fish feed to boost the growth, immune response, and protection against diseases for various fish species.…”

Section: Introductionmentioning

confidence: 99%

Length-weight relationship and condition factor of Nile tilapia (Oreochromis niloticus) fed diets supplemented with guava and star gooseberry leaf extract

Kamble,

Salin,

Chavan

et al. 2024

F1000Res

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Background Nile tilapia (Oreochromis niloticus) is predominant cultured species in aquaculture. However, there is a scarcity of literature regarding relationship between guava and star gooseberry leaf extract and the condition factor. Thus, the present study aims to investigate the effect of guava and star gooseberry leaf extract-supplemented diets on the specific growth rate, length-weight relationship, and condition factor of Nile tilapia. Methods Six hundred and thirty Nile tilapia (8.7±0.4 g) were randomly distributed among twenty-one tanks (30 fish per tank) within a recirculation system. Over a 60-day period, the fish were fed diets supplemented with 5g/Kg and 10g/Kg of guava leaf extract (GLE-5, GLE-10), star gooseberry leaf extract (SGLE-5, SGLE-10), and a mixture of both (MxLE-5, MXLE-10). Subsequently, specific growth rate, length-weight relationship, and condition factor were determined. Results After 60 days, the specific growth rate was significantly higher in all the GLE, SGLE, and MxLE groups compared to the control group. The final lengths and weights differed significantly both in the control group and all the GLE, SGLE, and MxLE groups. The analysis of the regression equation indicated a positive correlation (r = 0.970, 0.977, 0.976, 0.974, 0.974, 0.974, and 0.969) between the length and weight of Nile tilapia in the control group and in all the GLE, SGLE, and MxLE groups. The regression exponent "b" values in all the GLE, SGLE, and MxLE groups were >3, indicating a positive allometric growth pattern in Nile tilapia compared to the control (b=2.866), which exhibited a negative allometry. The final condition factor values did not differ significantly in either the control group or any of the plant extract groups. Conclusions Nile tilapia exhibited positive allometric growth patterns and maintained good health when fed with GLE, SGLE, and MxLE groups. Therefore, these plant extracts demonstrate suitability for commercial Nile tilapia production.

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Bioactive composition and antibacterial activity of three herbal extracts (lemongrass, sage, and guava leaf) against oral bacteria: An in vitro study

Cited by 13 publications

References 27 publications

Etnofarmacologia, Fitoquímica, Toxicologia E Atividades Anti-Inflamatória E Antinociceptiva De Folhas De Psidium Guajava L.: Uma Revisão

Etnofarmacologia, Fitoquímica, Toxicologia E Atividades Anti-Inflamatória E Antinociceptiva De Folhas De Psidium Guajava L.: Uma Revisão

Effects of dietary guava leaf aqueous extract supplementation on growth, antioxidant capacity, and non-specific immunity in mud crab Scylla paramamosain

Length-weight relationship and condition factor of Nile tilapia (Oreochromis niloticus) fed diets supplemented with guava and star gooseberry leaf extract

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