Bioactive components and preventive effect of green tea (Camellia sinensis) extract on post-laparotomy intra-abdominal adhesion in rats

Parsaei, Pouya; Karimi, Mehrdad; Asadi, Sayyed Yazdan; Rafieian-Kopaei, Mahmoud

doi:10.1016/j.ijsu.2013.08.014

Cited by 67 publications

(46 citation statements)

References 28 publications

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“…They have demonstrated promising effects in a wide variety of diseases such as cancer [16,17] , diabetes [18,19] , atherosclerosis and cardiovascular diseases [20][21][22][23] , learning and cognitive complications [24][25][26] , and wounds [27][28][29] . Furthermore, medicinal herbs are also effective in prevention and treatment of the toxicity induced by other drugs or toxins [30][31][32][33][34][35][36][37] .…”

Section: Introductionmentioning

confidence: 99%

Identification of medicinal plants effective in infectious diseases in Urmia, northwest of Iran

Bahmani

Saki

Shahsavari

et al. 2015

Asian Pacific Journal of Tropical Biomedicine

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A B S T R A C TObjective: To identify the medicinal plants effective in infectious diseases. Methods: Initially, we obtained a list of herbalists and traditional healers from Food and Drug Deputy. Direct observations and interviews as well as collection of herbarium specimens of indigenous medicinal plants effective in infectious diseases of urinary tract, reproductive, digestive, respiratory and skin systems were performed. This study was conducted through questionnaires and interviews; the questionnaires were distributed among traditional healers and simultaneous interviews were also run. The plants were herbariumized, herbarium specimens were authenticated, and their species were determined by using reliable flora and other sources. Finally, the data were input into Excel 2010 and analyses were performed. Results: Out of the studied plants, 35 native medicinal plants belonging to 17 families were effective in the treatment of various diseases and infections. In this study, the Lamiaceae family had the highest frequency of plants for the treatment of infections. Traditional healers of Urmia in 24% of cases used the leaves of medicinal herb to treat patients. In 68% of cases, they prescribed medicinal herbs in the boiled forms. Most medicinal herbs showed therapeutic effect on the digestive system. Conclusions: Traditional medicinal sources, valuable knowledge of traditional healers in Urmia, the scientific investigation of the effects of the herbs offered in this study and their effects in traditional medicine may provide a good source for new drugs in modern medicine.

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Section: Introductionmentioning

confidence: 99%

Identification of medicinal plants effective in infectious diseases in Urmia, northwest of Iran

Bahmani

Saki

Shahsavari

et al. 2015

Asian Pacific Journal of Tropical Biomedicine

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“…Therefore, applying proper strategies to prevent adhesions formation should be considered in all clinical and surgical settings. Several preventive methods and potential preventive agents have been studied, including lavage of abdominal cavity, lytic agents, macrophage promoting factors, nonsteroidal anti-nflammatory drugs, heparin, dextran 70, ringer lactate, antihistamine, prostaglandin synthesis inhibitors, calcium channel blockers, rofecoxib, and green tea extract [4][5][6][7][8] . These agents may indirectly prevent the creation of adhesions by inhibiting inflammatory processes leading to adhesion formation, or may act as physical barriers in separating injured surfaces 9 .…”

Section: ■ Introductionmentioning

confidence: 99%

The effectiveness of heparin, platelet-rich plasma (PRP), and silver nanoparticles on prevention of postoperative peritoneal adhesion formation in rats

et al. 2017

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Purpose: To assess the effectiveness of heparin, platelet-rich plasma (PRP), and silver nanoparticles on prevention of postoperative adhesion in animal models. Methods: Sixty males Albino Wistar rats aged 5 to 6 weeks were classified into five groups receiving none, heparin, PRP, silver nanoparticles, PRP plus silver nanoparticles intraperitoneally. After 2 weeks, the animals underwent laparotomy and the damaged site was assessed for peritoneal adhesions severity. Results: The mean severity scores were 2.5 ± 0.9, 2.16 ± 0.7, 1.5 ± 0.5, 2.66 ± 0.88, and 2.25 ± 0.62 in the control, heparin, PRP, silver and PRP plus silver groups, respectively with significant intergroup difference (p = 0.004). The highest effective material for preventing adhesion formation was PRP followed by heparin and PRP plus silver. Moreover, compared to the controls, only use of PRP was significantly effective, in terms of adhesion severity (p = 0.01). Conclusion: Platelet-rich plasma alone may have the highest efficacy for preventing postoperative peritoneal adhesions in comparison with heparin, silver nanoparticles and PRP plus silver nanoparticles.

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“…Human adenovirus (ADV) is a non-enveloped virus with a linear double-stranded DNA which encodes [30][31][32][33][34][35][36][37][38][39][40] proteins. Almost all of about 52 serotypes of this virus are associated with a wide range of human diseases including conjunctivitis, gastroenteritis, hepatitis, myocarditis, and pneumonia.…”

Section: Introductionmentioning

confidence: 99%

“…Moreover, the compounds found in teas present different biological properties, as established by the number of in vivo and in vitro studies [24], the main ones being antioxidants [25], anti-inflammatory [26], antisepticemic [23], anticarcinogenic [27][28][29], hypocholesterolemic [30], prevent postoperative intra-abdominal adhesions [31], provide antibacterial effect [32] and protection for the renal injury induced by contrast media [33].…”

Section: Introductionmentioning

confidence: 99%

Anti-adenovirus activity, antioxidant potential, and phenolic content of black tea (Camellia sinensis Kuntze) extract

Karimi

Moradi

Alidadi

et al. 2016

Journal of Complementary and Integrative Medicine

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BackgroundAdenovirus (ADV) causes a number of diseases in human, and to date, no specific antiviral therapy is approved against this virus. Thus, searching for effective anti-ADV agents seems to be an urgent requirement. Many studies have shown that components derived from medicinal plants have antiviral activity. Therefore, the present study was aimed to evaluate in vitro anti-ADV activity and also antioxidant potential and total phenolic compounds of black tea (Camellia sinensis) crude extract. MethodsIn this study, the hydroalchoholic extract of black tea was prepared and its anti-ADV activity was evaluated on HEp2 cell line using MTT [3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide] assay. The 50 % inhibitory concentration (IC50) and 50 % cytotoxicity concentration (CC50) of the extract were determined using regression analysis. Its inhibitory effect on adsorption and/or post-adsorption stages of the virus replication cycle was evaluated. To determine antioxidant activity, total phenol content, and flavonoids content of the extract, the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, Folin-Ciocalteu method, and aluminum chloride colorimetric method were used, respectively. ResultsThe CC50 and the IC50 of the extract were 165.95±12.7 and 6.62±1.4 µg/mL, respectively, with the selectivity index (SI) of 25.06. This extract inhibited ADV replication in post-adsorption stage. The IC50 of DPPH radical was 8±1.41 μg/mL, compared with butylated hydroxytoluene, with IC50 of 25.41±1.89 μg/mL. The total phenol and flavonoid contents of the extract were 341.8±4.41 mg gallic acid equivalent per gram and 21.1±2.11 mg/g, respectively. ConclusionsHaving SI value of 25.06 with inhibitory effect on ADV replication, particularly during the post-adsorption period, black tea extract could be considered as a potential anti-ADV agent. The antiviral activity of this extract could be attributed to its phenolic compounds.

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Bioactive components and preventive effect of green tea (Camellia sinensis) extract on post-laparotomy intra-abdominal adhesion in rats

Abstract: Green tea extract reduces intra-peritoneal adhesions in an animal model.

Cited by 67 publications

References 28 publications

Identification of medicinal plants effective in infectious diseases in Urmia, northwest of Iran

Identification of medicinal plants effective in infectious diseases in Urmia, northwest of Iran

The effectiveness of heparin, platelet-rich plasma (PRP), and silver nanoparticles on prevention of postoperative peritoneal adhesion formation in rats

Anti-adenovirus activity, antioxidant potential, and phenolic content of black tea (Camellia sinensis Kuntze) extract

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