BIOACCUMULATION OF POLYCHLORINATED BIPHENYLS (PCBs) AND DICHLORODIPHENYLETHANE (DDE) METHYL SULFONES IN TISSUES OF SEAL AND DOLPHIN MORBILLIVIRUS EPIZOOTIC VICTIMS

Troisi, G. M.; Haraguchi, Koichi; Kaydoo, DS; Nyman, Madeleine; Aguilar, Àlex; Borrell, Asunción; Siebert, Ursula; Mason, C. F.

doi:10.1080/00984100050201622

Cited by 49 publications

(32 citation statements)

References 20 publications

(39 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Although biological systems degrade small quantities of DDT into DDE methyl sulphones and other metabolites (Letcher et al, 2000;Troisi et al, 2001), most biotransformation processes in vertebrates end up as DDE (Peterle, 1991). Thus, the progressive degradation of the remnant organochlorine load and the absence of new inputs in the western Mediterranean are further demonstrated by the increase in the relative abundance of DDE forms within the DDT mixture, a process that has been commonly observed in other locations where recent releases of this group of chemicals have not taken place (Aono et al, 1997).…”

Section: Resultsmentioning

confidence: 98%

DDT and PCB reduction in the western Mediterranean from 1987 to 2002, as shown by levels in striped dolphins (Stenella coeruleoalba)

Aguilar

Borrell

2005

Marine Environmental Research

Self Cite

View full text Add to dashboard Cite

Section: Resultsmentioning

confidence: 98%

DDT and PCB reduction in the western Mediterranean from 1987 to 2002, as shown by levels in striped dolphins (Stenella coeruleoalba)

Aguilar

Borrell

2005

Marine Environmental Research

Self Cite

View full text Add to dashboard Cite

“…The preferential retention of congeners 4-110, 4 0 -132, and 4-149 in the brain may be explained by a higher affinity to the proteins of the brain. Special protein binding properties of MeSO 2 -PCBs were observed in other organs, for example, Clara-cell secretory protein in the lung and uteroglobin in the uterus of laboratory rats and marine mammals, for example, harbor seal (Phoca vitulina) and dolphin (Stenella coeruleoalba) [26][27][28]. No previously reported data for MeSO 2 -PCBs in the fish brain are available.…”

Section: Congener Profiles Of Meso 2 -Pcbsmentioning

confidence: 91%

Methylsulfonyl polychlorinated biphenyls in fish from an electronic waste‐recycling site in South China: Levels, congener profiles, and chiral signatures

Zhang

Luo

et al. 2012

Enviro Toxic and Chemistry

View full text Add to dashboard Cite

Abstract-Great concerns have been raised about the fate and effects of polychlorinated biphenyls (PCBs) and other organic contaminants contained in electronic waste (e-waste) exported from industrialized countries at midlatitudes to subtropical and tropical regions. Information on the metabolites of these chemicals, for example, methylsulfonyl-PCBs (MeSO 2 -PCBs) in wildlife from the later regions is scarce. In the present study, 17 MeSO 2 -PCBs, including five chiral congeners, were detected in the muscle, liver, and brain tissues of two benthic fish species-northern snakehead and mud carp-from a small pond near an electronic waste recycling site in South China. The mean concentrations of the sum of the MeSO 2 -PCBs ranged from 80 to 340 ng/g lipid weight in the tissues, with relative higher levels in the liver than the muscle and brain tissues. These levels were one order of magnitude greater than the highest levels of MeSO 2 -PCBs previously reported in fish. The 3 0 -MeSO 2 -CB 87, 3 0 -and 4 0 -MeSO 2 -CB 101, 4-MeSO 2 -CB 110, and 4-MeSO 2 -CB 149 were dominant, collectively comprising more than 55% of the total MeSO 2 -PCBs. Except for 4-MeSO 2 -

show abstract

“…MeSO 2 -PCBs have also been found in uterine fluid bound to uteroglobin in animal studies (Brandt et al, 1982) and in seals and dolphins (Brandt et al, 1982;Troisi et al, 2001). In experiments in rats, MeSO 2 -PCB causes reduction of thyroid hormone levels in serum and induction of drug metabolizing enzymes in the liver (Kato et al, 1998).…”

Section: Introductionmentioning

confidence: 96%

Maternal and cord serum exposure to PCB and DDE methyl sulfone metabolites in eastern Slovakia

et al. 2007

View full text Add to dashboard Cite

Polychlorinated biphenyls (PCBs) were commercially produced between 1959 and 1984 in eastern Slovakia. Improper handling led to a highly contaminated local environment and high levels of PCBs in humans and wildlife in the Michalovce area. The aim of this study was to analyse serum for methylsulfonyl metabolites of PCB (MeSO 2 -PCBs) and DDE (3-MeSO 2 -DDE) in serum samples from pregnant women and in a selected number of paired cord blood samples to assess maternal sulfone levels and patterns, and transplacental transfer of these metabolites. The donating women were from two districts in eastern Slovakia. A liquid-liquid extraction method together with separation of substance groups and further clean up on silica gel columns were applied prior to analysis by gas chromatography/mass spectrometry. 3-MeSO 2 -DDE was the major methyl sulfone in most of the samples followed by a yet not identified MeSO 2 -hexaCB, 4′-MeSO 2 -CB101, 4′-MeSO 2 -CB87 and 4-MeSO 2 -CB149. The women from the contaminated area had three times higher concentrations of the MeSO 2 -PCBs than women from the reference area. This is the first report on methyl sulfone metabolites of PCB and DDE in human cord serum. It is shown that these metabolites are transported through the placenta. The levels of MeSO 2 -PCBs in the maternal serum were about 1.5 times higher than in the corresponding cord serum on a lipid weight basis. For 3-MeSO 2 -DDE, the levels were about the same in maternal and cord serum. The difference in the maternal:cord ratio, comparing MeSO 2 -PCBs with 3-MeSO 2 -DDE might be due to differences in transport through the placenta caused by their different affinities for lipoproteins and plasma proteins.

show abstract

BIOACCUMULATION OF POLYCHLORINATED BIPHENYLS (PCBs) AND DICHLORODIPHENYLETHANE (DDE) METHYL SULFONES IN TISSUES OF SEAL AND DOLPHIN MORBILLIVIRUS EPIZOOTIC VICTIMS

Cited by 49 publications

References 20 publications

DDT and PCB reduction in the western Mediterranean from 1987 to 2002, as shown by levels in striped dolphins (Stenella coeruleoalba)

DDT and PCB reduction in the western Mediterranean from 1987 to 2002, as shown by levels in striped dolphins (Stenella coeruleoalba)

Methylsulfonyl polychlorinated biphenyls in fish from an electronic waste‐recycling site in South China: Levels, congener profiles, and chiral signatures

Maternal and cord serum exposure to PCB and DDE methyl sulfone metabolites in eastern Slovakia

Contact Info

Product

Resources

About