Bioaccessibility and transformations of selenium in the human intestine

Lavu, Rama; Wiele, Tom Van de; Pratti, Varalakshmi Lalithya; Tack, Filip; Laing, Gijs Du

doi:10.1201/b15960-22

Cited by 2 publications

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“…Microbiota living in human intestine can be responsible of these chemical form changes and can direct metal uptake according to the species and then influence bioaccessibility values and fluctuations. Actually, working on Se bioaccessibility in the human intestine, Lavu et al (2013) reported that Se bioaccessibility decreases to below 40 and 70 % after 48 h of colon incubation for SeMet and selenate, respectively. This phenomenon was attributed to bacteria cell fractions of gut contents and feces that uptake actively Se as a micronutrient for their metabolic processes.…”

Section: Selenium Gastric Bioaccessibility (Gb) In Maizementioning

confidence: 99%

Bioaccessibility of selenium after human ingestion in relation to its chemical species and compartmentalization in maize

Mombo

Schreck

Dumat

et al. 2015

Environ Geochem Health

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Selenium is a micronutrient needed by all living organisms including humans, but often present in low concentration in food with possible deficiency. From another side, at higher concentrations in soils as observed in seleniferous regions of the world, and in function of its chemical species, Se can also induce (eco)toxicity. Root Se uptake was therefore studied in function of its initial form for maize (Zea mays L.), a plant widely cultivated for human and animal food over the world. Se phytotoxicity and compartmentalization were studied in different aerial plant tissues. For the first time, Se oral human bioaccessibility after ingestion was assessed for the main Se species (Se(IV) and Se(VI)) with the BARGE ex vivo test in maize seeds (consumed by humans), and in stems and leaves consumed by animals. Corn seedlings were cultivated in hydroponic conditions supplemented with 1 mg L(-1) of selenium (Se(IV), Se(VI), Control) for 4 months. Biomass, Se concentration, and bioaccessibility were measured on harvested plants. A reduction in plant biomass was observed under Se treatments compared to control, suggesting its phytotoxicity. This plant biomass reduction was higher for selenite species than selenate, and seed was the main affected compartment compared to control. Selenium compartmentalization study showed that for selenate species, a preferential accumulation was observed in leaves, whereas selenite translocation was very limited toward maize aerial parts, except in the seeds where selenite concentrations are generally high. Selenium oral bioaccessibility after ingestion fluctuated from 49 to 89 % according to the considered plant tissue and Se species. Whatever the tissue, selenate appeared as the most human bioaccessible form. A potential Se toxicity was highlighted for people living in seleniferous regions, this risk being enhanced by the high Se bioaccessibility.

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Section: Selenium Gastric Bioaccessibility (Gb) In Maizementioning

confidence: 99%

Bioaccessibility of selenium after human ingestion in relation to its chemical species and compartmentalization in maize

Mombo

Schreck

Dumat

et al. 2015

Environ Geochem Health

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The Level of Toxic Elements in Edible Crops from Seleniferous Area (Punjab, India)

Skalnaya

Jaiswal

Prakash

et al. 2017

Biol Trace Elem Res

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The primary objective of the present study was to assess the level of selenium and toxic trace elements in wheat, rice, maize, and mustard from seleniferous areas of Punjab, India. The content of selenium (Se) and toxic trace elements, including aluminum (Al), arsenic (As), cadmium (Cd), mercury (Hg), nickel (Ni), lead (Pb), and tin (Sn), in crop samples was assessed using inductively coupled plasma mass-spectrometry after microwave digestion of the samples. The obtained data demonstrate that cultivation of crops on seleniferous soils significantly increased Se level in wheat, mustard, rice, and maize by a factor of more than 590, 111, 85, and 64, respectively. The study also showed that Se exposure affected toxic metal content in crops. In particular, Se-rich wheat was characterized by a significant decrease in Al, As, Ni, Pb, and Sn levels. The level of As, Cd, Ni, Pb, and Sn was significantly decreased in Se-rich rice, whereas As content was increased. In turn, the decrease in Al, As, Cd, Ni, Pb, and Sn levels in Se-rich maize was associated with a significant elevation of Hg content. Finally, Se-rich mustard was characterized by a significant increase in Al, As, and Hg levels, while the content of Ni, Pb, and Sn was significantly lower than the control levels. These findings should be taken into account while developing the nutritional strategies for correction of Se status. At the same time, the exact mechanisms underlying the observed differences are to be estimated.

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Bioaccessibility and transformations of selenium in the human intestine

Cited by 2 publications

References 1 publication

Bioaccessibility of selenium after human ingestion in relation to its chemical species and compartmentalization in maize

Bioaccessibility of selenium after human ingestion in relation to its chemical species and compartmentalization in maize

The Level of Toxic Elements in Edible Crops from Seleniferous Area (Punjab, India)

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