Bio Synthesis and Characterization of Silver Nanoparticles Using <i>Lagenaria siceraria</i> Leaf Extract and their Antibacterial Activity

Abstract

The present investigation demonstrates the formation of silver nanoparticles by the reduction of the aqueous silver metal ions during exposure to the Lagenaria siceraria leaf extract. The synthesized AgNPs have characterized by UV-visible spectroscopy, X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FT-IR) techniques. AgNPs formation has screened by UV-visible spectroscopy through colour conversion due to surface plasma resonance band at 427 nm. X-ray diffraction (XRD) confirmed that the resulting AgNPs are highly crystalline and the structure is face centered cubic (fcc). FT-IR spectrum indicates the presence of different functional groups present in the biomolecules capping the nanoparticles. Further, inhibitory activity of AgNPs and leaf extract were tested against human pathogens like gram-pastive (Staphylococcus aureus, Bacillus subtilis), gram-negative (Escherichia coli and Pseudomonas aeruginosa). The results indicated that the AgNPs showed moderate inhibitory actions against human pathogens than Lagenaria siceraria leaf extract, demonstrating its antimicrobial value against pathogenic diseases.

Larvicidal Efficacy and Characterization of Silver Nanoparticles Derived from Aqueous Leaves Extracts of Trichosanthes tricuspidata against Dengue Vector Ades aegypti

“…This result confirming the synthesis of silver nanoparticles due to reduction of Ag ions by the phytochemicals present in the T. tricuspidata extract. Similar results were observed from the plant extracts of Momordica charantia (8) and Lagenaria siceraria (9) . Due to the excitation of surface plasmon vibrations in the silver nanoparticles the color changes denoted silver nanoparticles formation (10) .…”

Ecofriendly Synthesis of Silver Nanoparticles Using Ethno Medicinal Plant Leaf Extract (<i>Jasminum auriculatum</i>) and their Antibacterial Properties

“…Antibacterial activity of silver nanoparticles is investigated against Enterococcus faecalis, Staphylococcus aureus (gram-positive ), Pseudomonas aeruginosa, E. coli (gram-negative) by disc diffusion method [31,32] are shown in Fig.8.…”

Enhancing malaria control using Lagenaria siceraria and its mediated zinc oxide nanoparticles against the vector Anopheles stephensi and its parasite Plasmodium falciparum

“…Roopan et al 9 and Anandh et al 45 claimed that the extract of Lagenaria siceraria is used in the therapy of large varieties of diseases like ascites, beriberi, and anasarca (edema). Further, the plant has been widely used for various treatment purposes that include antibacterial 45 , cytotoxic 46 , 47 and anti-malaria activities 48 . However, those studies applied different NPs but not much in ZnO NPs.…”