Bio‐Oss® blocks combined with BMP‐2 and VEGF for the regeneration of bony defects and vertical augmentation

Abstract

In the chosen setting and time frame, de novo bone formation did not increase with the additional use of growth factors.

Deferoxamine Restores Callus Size, Mineralization, and Mechanical Strength in Fracture Healing after Radiotherapy

“…11 In addition, recent studies have demonstrated the osteogenic stimulus of VEGF to be comparable to bone morphogenetic protein 2 (BMP-2) in vivo. 12,13 …”

Sequential healing of onlay bone grafts using combining biomaterials with cross‐linked collagen in dogs

“…Although some clinical and preclinical studies reported successful use of bovine hydroxyapatite block for ridge augmentation (Hammerle et al 2008;Rothamel et al 2009), most of preclinical studies have shown the inferior healing potential with a limited amount of new bone formation compared with autogenous block bone graft (Araujo et al 2002;De Santis et al 2012Schmitt et al 2013). Such hardtype block materials often need to be trimmed in order to conform to the irregular configuration of an osseous defect.…”

Long‐term changes in graft height after maxillary sinus augmentation, onlay bone grafting, and combination of both techniques: a long‐term retrospective cohort study

“…In many cases, especially those involving severe atrophy of the jaws, bone augmentation is needed prior to implant placement (Weingart et al 1992;Schliephake et al 1997 Esposito et al 2009;Farhat et al 2008). Vertical augmentation can be performed by onlay bone grafting of the alveolar crest, sinus floor elevation, or combinations of these methods (Neyt et al 1997;Wilkert-Walter et al 2002;Wallace & Froum 2003;Wiltfang et al 2005;Nkenke & Stelzle 2009;Raja 2009;Schmitt et al 2011Schmitt et al , 2012. However, augmented bone is subject to conversion processes, which can lead to a considerable decrease in bone over time after augmentation (Binger & Hell 1999;Wiltfang et al 2005).…”