Binge Eating Disorder: The Search for Better Treatments

Yager, Joel

doi:10.1176/foc.7.4.foc499

Cited by 16 publications

(19 citation statements)

References 9 publications

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“…The level of physical activity reported by obese individuals who binge is approximately half of that of an age and weight matched community sample (Levine et al, 1996). Because of the severe co-morbid psychiatric and physical conditions, BED has been characterized as one of the most difficult psychiatric conditions to treat (Yager, 2008).…”

Section: Introductionmentioning

confidence: 99%

Changes in physical activity, physical fitness, self-perception and quality of life following a 6-month physical activity counseling and cognitive behavioral therapy program in outpatients with binge eating disorder

Vancampfort

Probst

Adriaens

et al. 2014

Psychiatry Research

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Changes in physical activity, physical fitness, self-perception and quality of life following a six-month physical activity counseling and cosgnitive behavioral therapy program in outpatients with binge eating disorder, Psychiatry Research, http://dx.doi.org/10. 1016/j.psychres.2014.05.016 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting galley proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. AbstractThe aim of the current study was to explore the associations between changes in the number of binges, physical activity participation, physical fitness, physical self-perception and quality of life following a six-month physical activity counseling and cognitive behavioral program in patients with binge eating disorder (BED). In total 34 (31 women) outpatients with BED (38.5±10.7 years) completed a six-month one-day per week group-based program.Participants completed the 36-item Short Form Health Survey, the Baecke Physical Activity questionnaire, the Physical Self Perception Profile and performed a six-minute walk test (6MWT) at baseline, after three and six months. Except for physical activity at work, physical strength and self-worth perception, all parameters significantly improved after six months.The effect sizes ranged from -0.33 for the number of binges to 1.67 for participation in sports activities. Significant increases in leisure time physical activity were associated with significant improvements in physical health related quality of life, perceived sports competence and physical fitness and in perceived body attractiveness. The significant reduction in the number of binges was associated with significant improvements in physical health related quality of life. Future research should focus on detailing which techniques can stimulate physical activity participation in patients with BED.

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Section: Introductionmentioning

confidence: 99%

Changes in physical activity, physical fitness, self-perception and quality of life following a 6-month physical activity counseling and cognitive behavioral therapy program in outpatients with binge eating disorder

Vancampfort

Probst

Adriaens

et al. 2014

Psychiatry Research

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“…However, their administration is associated with a variety of adverse side effects, which represent serious problems during chronic treatment (McElroy et al, 2009;Carter et al, 2003;Yager, 2008). In particular, sibutramine has been recently withdrawn from the European market, while topiramate is well known for its cognitive impairing properties.…”

Section: Introductionmentioning

confidence: 99%

Role of Orexin-1 Receptor Mechanisms on Compulsive Food Consumption in a Model of Binge Eating in Female Rats

Piccoli

Bonaventura

Cifani

et al. 2012

Neuropsychopharmacol

141

102

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Orexins (OX) and their receptors (OXR) modulate feeding, arousal, stress, and drug abuse. Neural systems that motivate and reinforce drug abuse may also underlie compulsive food seeking and intake. Therefore, the effects of GSK1059865, a dual OX 1 /OX 2 R antagonist were evaluated in a binge eating (BE) model in female rats. BE of highly palatable food (HPF) was evoked by three cycles of food restriction followed by stress, elicited by exposing rats to HPF, but preventing them from having access to it for 15 min. Pharmacokinetic assessments of all compounds were obtained under the same experimental conditions used for the behavioral experiments. Topiramate was used as the reference compound as it selectively blocks BE in rats and humans. Dose-related thresholds for sleep-inducing effects of the OXR antagonists were measured using polysomnography in parallel experiments. SB-649868 and GSK1059865, but not JNJ-10397049, selectively reduced BE for HPF without affecting standard food pellet intake, at doses that did not induce sleep. These results indicate, for the first time, a major role of OX 1 R mechanisms in BE, suggesting that selective antagonism at OX 1 R could represent a novel pharmacological treatment for BE and possibly other eating disorders with a compulsive component.

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“…Due to severe co-morbid psychiatric and physical conditions the multidisciplinary treatment of BED is a clinical challenge (Yager, 2008). The treatment for people with BED is mainly focused on improving key parameters such as weight and body shape concerns, body dissatisfaction, health related quality of life, obesity and physical inactivity (Vanderlinden, Buis, Pieters, & Probst, 2007).…”

Section: Introductionmentioning

confidence: 99%

Binge Eating Disorder: The Search for Better Treatments

Cited by 16 publications

References 9 publications

Changes in physical activity, physical fitness, self-perception and quality of life following a 6-month physical activity counseling and cognitive behavioral therapy program in outpatients with binge eating disorder

Changes in physical activity, physical fitness, self-perception and quality of life following a 6-month physical activity counseling and cognitive behavioral therapy program in outpatients with binge eating disorder

Role of Orexin-1 Receptor Mechanisms on Compulsive Food Consumption in a Model of Binge Eating in Female Rats

Top 10 research questions to promote physical activity research in people with binge eating disorder

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