Binding Mechanisms in Supramolecular Complexes

Abstract

Supramolecular chemistry has expanded dramatically in recent years both in terms of potential applications and in its relevance to analogous biological systems. The formation and function of supramolecular complexes occur through a multiplicity of often difficult to differentiate noncovalent forces. The aim of this Review is to describe the crucial interaction mechanisms in context, and thus classify the entire subject. In most cases, organic host-guest complexes have been selected as examples, but biologically relevant problems are also considered. An understanding and quantification of intermolecular interactions is of importance both for the rational planning of new supramolecular systems, including intelligent materials, as well as for developing new biologically active agents.

Solvent effects in the extraction and detection of polycyclic aromatic hydrocarbons from complex oils in complex environments

“…Moreover, the only solvent systems that led to a quantifiable energy transfer peak were those that contained sodium chloride (Table 7), which is further confirmed by the ability of these solvent systems to promote stronger fluorescence via direct excitation of the fluorophore ( Figure 9). In general, non-covalent cyclodextrin based complexes rely on a variety of intermolecular interactions, including hydrophobic association, intermolecular hydrogen bonding, and electrostatic and steric complementarity [38]. Many of these forces are known to depend strongly on experimental conditions, including in particular the composition of the solvent and the presence of solvent additives [39][40][41].…”

One-Pot Synthesis, Crystal Structures and Thermal Properties of Two Three-Dimensional Cobalt(II) Complexes

“…[1][2][3][4][5][6][7][8][9] It is widely acknowledged that the coordinative bonding is the primary interaction to sustain the network, while supramolecular interactions, such as hydrogen bonding, π-π stacking interactions and Van der Waals forces are also believed to play important roles. [10][11][12][13][14][15][16][17] To date, a variety of supramolecular polymers with complicated architectures and interesting properties based on different bridging ligands especially aromatic polycarboxylate ligands have been synthesized successfully.…”

Strongly underestimated dispersion energy in cryptophanes and their complexes

“…Of high interest are noncovalent host-guest interactions which are mainly dominated by London forces [1][2][3][4][5][6] . The latter are considered as weak molecular interactions and increase with the size of the interacting moieties.…”