Binding and stabilization of curcumin by mixed chitosan–surfactant systems: A spectroscopic study

Stabilization of diketo tautomer of curcumin by premicellar anionic surfactants: UV–Visible, fluorescence, tensiometric and TD-DFT evidences

“…The changes in fluorescence behavior of curcumin have been attributed to the solute-solvent interactions, intramolecular charge transfer character, intermolecular hydrogen bonding with polar solvents, and p-p interaction with molecules possessing aromatic entity [57]. The plots of fluorescence intensity (FI) vs. concentration of the surfactants are shown in Fig.…”

Development and Validation of High Performance Liquid Chromatography Method for Simultaneous Estimation of Curcuminoids from Rhizome Extracts

“…The absorption maxima around 425 nm region is due to the enol group and that at 360 nm is due to the keto group. Since polar solvents facilitated the existence of enol form [73][74][75], the wavelength is selected at 425 nm.…”

Effect of Association of Curcumin with Chitosan in Presence of TX 100 on Its Degradation

“…Assuming 1:1 complex formation between chitosan and curcumin, linear plot has been made by following the absorbance changes at a suitable wavelength, as a function of reciprocal concentration of chitosan or curcumin according to the equation, the modified Benesi-Hildebrand equation (3) is given below [24][25][26] :…”

“…[18] The useful features of chitosan, e.g., its abundance, flexibility, nontoxicity, hydrophilicity, biocompatibility, biodegradability, antibacterial property, and high resistance to heat makes chitosan suitable for biomedical application such as drug delivery, tissue engineering, wound dressing, etc. [18][19][20][21][22][23][24][25][26][27][28] Because of the high content of amine functional groups, as well as the hydroxyl groups on the glucosamine unit (Scheme 1), the protonated amine groups can attract metal anions, viz., molybdate, vanadate, palladate, chromate, cadmium, etc., and can absorb a number of dyes such as reactive, basic, acidic, disperse dyes in acidic (pH < 5) solutions. [29][30][31][32][33] Chitosan also binds the herbal pigment curcumin with high affinity at considerably high pH (7.0-10.5) through its glucosamine unit.…”

“…Recently we have reported the stabilization of curcumin by mixed chitosan-surfactant systems and by premicellar anionic surfactant systems. [24,25] In extension of the same, the present work was carried out to study the association of curcumin with chitosan-TX 100 system and to determine the effect of such association on the stability of curcumin at physiological pH.…”