Bimaxillary Oral Focal Mucinosis

Abstract

Oral focal mucinosis is considered as oral counterpart of cutaneous focal mucinosis. The preoperative diagnosis of mucinosis is almost impossible because of its rarity and clinical similarity to other lesions of various etiologies. The histological diagnosis of oral mucinosis is important to better understand the etiopathogenesis, treatment modalities, and any recurrence of the lesion besides differentiating from the other soft tissue lesions.The purpose of this paper is to report the first case of bimaxillary involvement with dome-shaped elevated, rounded, asymptomatic, normally colored swelling in left posterior palatal mucosa and left mandibular posterior region in a 25-year old woman who was diagnosed as oral focal mucinosis histopathologically.

Oral focal mucinosis of the mandible in an adolescent patient

“…The treatment of choice in this patient was complete surgical excision of her soft tissue lesion, which is the accepted method for OFM in previously noted case reports 5 6 8. There are rare reports of recurrence, with one recurrence noted due to incomplete excision 14.…”

“…This case report depicts the lesion of OFM on the left mandible gingiva of an adolescent patient. The aetiology of this lesion is unclear, though a study by Neto et al suggested trauma could be the predisposing factor 5. Previous studies have mentioned overproduction of hyaluronic acid by surrounding fibroblasts in the stroma, which intrudes into the surrounding collagen 1–4 10.…”

“…There have been several reported cases of OFM in the adolescent and paediatric populations, as young as 2 years of age. Most case reports describe a single lesion, though Yadav et al reported a bi-maxillary case in 2016 5. Overall, this is a relatively rare lesion, with about 68 reported cases since Tomich originally reported his case series in 1974 1…”

“…OFM occurs mainly in adults in the fourth to fifth decade of life, although there have been few case reports in a child as young as 2 years of age 2 3. There is a distinct ratio favouring females to males, with an approximate ratio of 3:1, with the gingival origin being the most common, followed by in the hard palate, buccal mucosa, tongue, retromolar region and lip 1 4–7…”

Oral focal mucinosis: A multi‐institutional study and literature review

“…Other anatomical sites included buccal mucosa, tongue, retromolar trigone, and lips. There were also two rare cases of bilateral lesions on the palate 33,34 . Clinically, OFM presented as a submucosal sessile or pedunculated nodule, measuring from 0.5 to 4.5 cm (mean 1.10 cm, SD 0.72) and soft to firm in consistency.…”