Biliary tract intraductal papillary mucinous neoplasm: Report of 19 cases

Wang, Xing; Cai, Yunqiang; Chen, Yonghua; Liu, Xu-Bao

doi:10.3748/wjg.v21.i14.4261

Cited by 38 publications

(45 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Intrahepatic IPNBs are more similar to IPMN than the extrahepatic type histopathologically. 12 In a study published by Wang et al with 19 cases, 10 out of 19 tumor showed mucin secretion [14]. The frequency of phenotypes in IPNBs are pancreaticobiliary (45%), gastric (25%), intestinal (20%) and oncocytic (10%), respectively.…”

Section: Discussionmentioning

confidence: 96%

“…6 Again in two series with 19 and 32 cases showed almost 50% malignancy with IPNB. 14 Zen et al indicates in their study that IPNB is a more aggressive tumor than IPMN-P and the prognosis of patients with invasive IPNB is poorer than IPMN-P. 9 Focal dilatation of extra or intrahepatic biliary tree, intraductal masses and growth pattern through the interior wall are considered as a warning to suspect from IPNB.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Intraductal papillary neoplasm of bile ducts: report of a case and literature review

et al. 2019

View full text Add to dashboard Cite

A 67 year old male with right upper quadrant abdominal pain diagnosed with intraductal papillary neoplasm of bile ducts (IPNB) by endoscopic biopsy. The patient was treated surgically and disease free on first year follow-up. Intraductal papillary neoplasm of bile duct (IPNB) is a rare entity with malignant counterparts and recently classified by The World Health Organization. The aim of this study is to present a case of IPNB and review the literature. Pubmed/MEDLINE was searched and articles were extracted. Twenty four case reports and 17 retrospective case series were evaluated. From 41 studies, 824 cases were included. There was slight male predominancy among patients and almost all cases were from eastern countries. Even though the etiology remains unclear, hepatolithiasis was the most common potential etiological association. Most cases were treated with surgical intervention. More than half of the 577 resected specimens had invasive component. Incidence rate of histopathological subtypes were as fallowed: Intestinal (35%), pancreaticobiliary (32%), gastric (19%) and oncocytic (12%). Intraductal papillary neoplasm of bile duct has an increased malignancy rates at postoperative pathological diagnosis, consequently early surgical management is important.

show abstract

Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

Intraductal papillary neoplasm of bile ducts: report of a case and literature review

et al. 2019

View full text Add to dashboard Cite

show abstract

“…IPMN usually arises from the pancreatic duct. In the literature, there are few reported cases of IPMN arising from the biliary tree [9, 11, 12, 13, 14]. …”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Intraductal Papillary Mucinous Neoplasm of the Biliary Duct in a Patient with Prostate Adenocarcinoma

Parekh

Krol

Piraka

et al. 2016

Case Rep Gastroenterol

View full text Add to dashboard Cite

Intraductal papillary mucinous neoplasms (IPMNs) are mucin-producing papillary neoplasms of the pancreatic or biliary ductal system that exhibit variable cellular atypia and cause ductal dilation. There are few reported cases of IPMN arising from the biliary tree in the literature. It has a higher propensity to undergo malignant transformation compared to IPMN arising from the pancreatic duct. An 80-year-old male underwent cross-sectional tomography (CT) imaging of the abdomen for evaluation of prostate adenocarcinoma, which revealed an incidental 2.3 × 2.7 cm soft tissue mass centered at the porta hepatis with diffuse dilatation of the left intrahepatic biliary ductal system and mild prominence of the right intrahepatic ductal system. Endoscopic ultrasound showed 2 adjacent hilar masses involving the common hepatic duct and the left hepatic duct with protrusion of the tissue into the lumen of the duct and upstream ductal dilatation. Endoscopic retrograde cholangiopancreatography revealed a large filling defect in the common hepatic duct extending into the left hepatic duct. A large amount of clot and soft tissue with a fish-egg appearance was retrieved. The patient underwent left hepatic lobectomy, radical resection of the common hepatic duct with Roux-en-Y hepaticojejunostomy to the right hepatic duct. Histopathological examination of the resected specimen revealed intraductal papillary mucinous neoplasm with diffuse high-grade dysplasia. Follow-up CT scan of the abdomen 2 months after the surgery was negative for any masses.

show abstract

“…1 This clinical entity is a precursor of invasive carcinoma, and 40-80% of resected IPMN-Bs contain invasive components. 2 Therefore, most cases are treated surgically. However, conservative therapy was considered for inoperable patients with compli- Intraductal papillary mucinous neoplasm of the bile duct (IPMN-B) is frequently found and has recently been recognized as a precancerous lesion leading to invasive carcinoma characterized by papillary growth of the ductal epithelium with rich mucin production and cystic dilatation of the hepatic duct.…”

Section: Introductionmentioning

confidence: 99%

Intraductal Papillary Mucinous Neoplasms of the Bile Duct Treated with Argon Plasma Coagulation

Park¹,

Baek²,

Kim³

et al. 2017

Korean J Pancreas Biliary Tract

View full text Add to dashboard Cite

Biliary tract intraductal papillary mucinous neoplasm: Report of 19 cases

Abstract: BT-IPMN is a rare biliary entity. Complete resection of the tumor is associated with good survival, even in patients with malignant disease.

Cited by 38 publications

References 23 publications

Intraductal papillary neoplasm of bile ducts: report of a case and literature review

Intraductal papillary neoplasm of bile ducts: report of a case and literature review

A Rare Case of Intraductal Papillary Mucinous Neoplasm of the Biliary Duct in a Patient with Prostate Adenocarcinoma

Intraductal Papillary Mucinous Neoplasms of the Bile Duct Treated with Argon Plasma Coagulation

Contact Info

Product

Resources

About