Biliary pain in postcholecystectomy patients without biliary obstruction

Grimon, G.; Buffet, Catherine; André, L.; Etienne, J P; Desgrez, A.

doi:10.1007/bf01318203

Cited by 14 publications

(5 citation statements)

References 17 publications

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“…Although initial experience was generally favourable (65-71), there was variability in the parameters used for scintigraphy and diagnostic criteria for SO dysfunction. Sphincterotomy has been shown to improve bile flow, often to normal values (68)(69)(70). One study (72) assessed many scintigraphic variables and found that the hepatic hilum to duodenal transit time is the best predictor of delayed bile flow into the duodenum.…”

Section: Mechanism Of So Dysfunctionmentioning

confidence: 99%

Sphincter of Oddi Function and Dysfunction

Toouli

Craig²

2000

Canadian Journal of Gastroenterology

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The sphincter of Oddi (SO) is situated at the junction of the bile and pancreatic ducts where they enter the duodenum, and it serves to regulate the flow of bile and pancreatic juices as well as to prevent the reflux of duodenal contents into the pancreatobiliary system. SO dysfunction relates to either the biliary or pancreatic portions of the sphincter. Distinct clinical syndromes relating to either sphincter segment are recognized. The mechanism of dysfunction remains uncertain, but disruption of neural pathways involved in sphincter function seems likely. SO dysfunction is best diagnosed by manometry, which is able to correctly stratify patient groups and determine therapy. Biliary scintigraphy, which is noninvasive, has shown promise as a screening tool for patients with suspected SO dysfunction. Division of the sphincter is an effective treatment for patients with manometrically proven SO stenosis for either the biliary or pancreatic form of the disorder. Other forms of SO dysfunction may benefit from pharmacotherapy.

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Section: Mechanism Of So Dysfunctionmentioning

confidence: 99%

Sphincter of Oddi Function and Dysfunction

Toouli

Craig²

2000

Canadian Journal of Gastroenterology

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“…This is a minimally invasive investigation that has the potential to provide useful data regarding flow dynamics across the SO. Initial studies did not show a strong correlation with either manometric findings or treatment outcome [25][26][27], but further refinements in the evaluation of the scintigraphic variables being analyzed have demonstrated correlation with SO manometry. As such, this investigation may be useful as a screening method for selecting patients for manometry [28,29].…”

Section: Diagnosis Of Sphincter Of Oddi Dysfunctionmentioning

confidence: 94%

Clinical aspects of sphincter of oddi function and dysfunction

Toouli

Craig

1999

Curr Gastroenterol Rep

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The sphincter of Oddi (SO) functions to regulate the flow of bile and pancreatic juices as well as to prevent the reflux of duodenal contents into the pancreatobiliary system. When dysfunction of the sphincter occurs, symptoms develop relating to either the biliary or pancreatic portions of the sphincter. The mechanism of this dysfunction remains speculative. SO manometry remains the "gold standard" to correctly diagnose the disorder and stratify therapy. Division of the sphincter is effective for SO stenosis, but there is no proven therapy for SO dyskinesia.

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“…administration of [99Tcm]‐diethyl iminodiacetic acid or a related compound and gives quantitative and qualitative information by measuring the time of the radionucleotide emptying from the liver and the biliary tract. Early studies were encouraging and suggested that it could replace SOM in the diagnosis of SOD 27–32 . Sostre et al 33 .…”

Section: Methodsmentioning

confidence: 99%