Biliary excretion of essential trace elements in rats under oxidative stress caused by selenium deficiency

Yamasaki, Kosuke; Sakuma, Yasunobu; Sasaki, Junya; Matsumoto, Shingo; Anzai, Kazunori; Matsuoka, K.; Honda, Chikako; Tsukada, Masamichi; Endo, Kazutoyo; Enomoto, Shuichi

doi:10.1007/s00216-011-5333-4

Cited by 6 publications

(2 citation statements)

References 36 publications

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“…In contrast to Fe and Zn, the Cu levels in rat liver tissue increased as a result of Se deficiency. Yamasaki et al (2011) observed decreased biliary excretion of Se, As, Mn, Fe, and Zn under Se-deficient conditions compared with that in normal rats and the enhanced biliary excretion of Mn and As in Se-adequate conditions. These observations were related to the element complexation with glutathione (GSH).…”

Section: Resultsmentioning

confidence: 63%

Effect of selenium-enriched defatted rape seeds on tissue cadmium and essential elements utilization in rats

Myška¹,

Száková²,

Fučíková³

et al. 2016

CZECH J ANIM SCI

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ABSTRACT:The effect of selenium-enriched defatted rapeseeds (DRS) added to the diet on Se uptake by rat organisms (whole blood, liver, kidney) was investigated in model conditions. Additionally, the response of other essential trace and major mineral elements (Cu, Ca, Fe, K, Mg, Mn, P, S, and Zn) in rat organisms on selenium and/or DRS addition was assessed. The experimental diets for the individual experimental groups were prepared as follows: group DRS 0 (control diet), group DRS 30 (30% of soybean meal in the diet replaced with DRS), group DRS60 (60% of soybean meal in the diet replaced with DRS), and group DRS100 (100% of soybean meal in the diet replaced with DRS), either unenriched or naturally fortified with Se. Whereas Se content in the blood and liver of the animals remained unchanged, increased Se levels were observed in kidney of the selenized DRS100 group compared to the others. Moreover, the results showed decreasing Cd content in the rat liver with increasing Se content in the diet, confirming antagonism of these elements. Concerning the essential elements, the application of the selenized DRS did not result in any serious imbalance in the utilization of these elements. In contrast, Se addition seems to be helpful for the improved utilization of essential elements such as P, S, and Zn, compared to the DRS-containing diet without Se fortification.

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Section: Resultsmentioning

confidence: 63%

Effect of selenium-enriched defatted rape seeds on tissue cadmium and essential elements utilization in rats

Myška¹,

Száková²,

Fučíková³

et al. 2016

CZECH J ANIM SCI

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“…Zn is also present in the structure of SOD enzyme as much as copper is present. The element Zn, which is present in the plasma freely, is the cofactor of SOD enzyme; it binds with biological molecules and prevents Fe and Cu from binding those molecules; hence, it prevents the oxidative damage that may occur (Khaled et al, 1997; Yamasaki et al, 2011). Both Cu and Zn amounts in the kidney and lung tissues and the serum show parallel increase or decrease.…”

Section: Discussionmentioning

confidence: 99%

Trace and major element levels in rats after oral administration of diesel and biodiesel derived from opium poppy (Papaver somniferum L.) seeds

Aksoy

Sözbilir

2013

Toxicol Ind Health

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The study investigated the toxic effects of diesel and biodiesel derived from opium poppy (Papaver somniferum L.) oil seeds on the trace and major elements in kidney, lung, liver, and serum of rats. By the end of 21 days, trace and major element concentrations in kidney, lung, and liver tissues and the serum were measured using inductively coupled plasma-optical emission spectroscopy. We observed that trace and major element levels in kidney, lung, and liver tissues and the serum changed. Especially, important differences were detected in trace and major element concentrations in kidney and lung tissues. In kidney tissue, the concentration differences of calcium, sodium, and zinc (Zn) were found between diesel and biodiesel groups. In lung tissue, the concentration differences of cadmium, lithium, magnesium, manganese, and Zn were found between diesel and biodiesel groups. Among the significant findings, Zn concentration in serum and liver tissue of diesel and biodiesel were different from control (p < 0.05). However, the metal levels of biodiesel group were similar to control group. Due to lesser toxicity of biodiesel, it could be considered as an alternate fuel.

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Neutron Activation Analysis: Application in Bioanalytical Sciences

Chajduk

Polkowska-Motrenko

2022

Handbook of Bioanalytics

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Biliary excretion of essential trace elements in rats under oxidative stress caused by selenium deficiency

Cited by 6 publications

References 36 publications

Effect of selenium-enriched defatted rape seeds on tissue cadmium and essential elements utilization in rats

Effect of selenium-enriched defatted rape seeds on tissue cadmium and essential elements utilization in rats

Trace and major element levels in rats after oral administration of diesel and biodiesel derived from opium poppy (Papaver somniferum L.) seeds

Neutron Activation Analysis: Application in Bioanalytical Sciences

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