Biliary Atresia, Intestinal Malrotation, Partial Abdominal Heterotaxia, and Craniofacial Anomalies in a Newborn with Intrauterine Opiate Exposure

Erhart, Nora; Sinatra, Frank

doi:10.1097/00005176-199405000-00014

Cited by 5 publications

(6 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previous findings (Erhart and Sinatra, ; Sutherland and Ware, ) showed an association between prenatal cocaine use and HS. We could not investigate this in our population, because none of our cases or controls were exposed.…”

Section: Discussionmentioning

confidence: 81%

See 1 more Smart Citation

When the right (Drug) should be left: Prenatal drug exposure and heterotaxy syndrome

Veenendaal

Kusters

Oostra

et al. 2016

Birth Defects Research

View full text Add to dashboard Cite

Background Recent studies reported an association between prenatal propylthiouracil exposure and birth defects, including abnormal arrangement across the left–right body axis, suggesting an association with heterotaxy syndrome. Methods This case–control and case‐finding study used data from 1981 to 2013 from the EUROCAT birth defect registry in the Northern Netherlands. First, we explored prenatal exposures in heterotaxy syndrome (cases) and Down syndrome (controls). Second, we describe the specific birth defects in offspring of mothers using propylthiouracil (PTU) prenatally. RESULTS A total of 66 cases with heterotaxy syndrome (incidence 12.1 per 100,000 pregnancies) and 783 controls with Down syndrome (143.3 per 100,000 pregnancies) were studied. No differences in intoxication use during pregnancy were found between cases and controls, including smoking (28.0% vs. 22.7%; p = 0.40), alcohol (14.0% vs. 26.9%; p = 0.052), and recreational drugs (0 vs. 0.3%; p = 1.00). We found an association between heterotaxy syndrome and prenatal drug exposure to follitropin‐alfa (5.6% vs. 1.1%; p = 0.04), and drugs used in nicotine dependence (3.7% vs. 0.2%; p = 0.02). Five mothers used PTU during pregnancy and gave birth to a child with trisomy 18, renal abnormalities, or hypospadias and cardiac defects. Conclusion This study identified follitropin‐alfa and drugs used in nicotine dependence as possible teratogens of heterotaxy syndrome. Our data suggest the possibility that there is an increased risk of birth defects (including renal, urological, and cardiac abnormalities) in children born among mothers taking PTU prenatally, but not for heterotaxy syndrome. Birth Defects Research (Part A) 106:573–579, 2016. © 2016 Wiley Periodicals, Inc.

show abstract

Section: Discussionmentioning

confidence: 81%

“…Also, the use of cocaine prenatally during the first trimester has been reported with HS (Kuehl and Loffredo, 2002;Sutherland and Ware, 2009). Opiate exposure (heroin and methadone) was also suggested as a risk factor after documentation in a patient with asymmetry defects (Erhart and Sinatra, 1994).…”

Section: Introductionmentioning

confidence: 99%

When the right (Drug) should be left: Prenatal drug exposure and heterotaxy syndrome

Veenendaal

Kusters

Oostra

et al. 2016

Birth Defects Research

View full text Add to dashboard Cite

show abstract

“…Also, the presence of situs abnormalities with BA has been reported [13]. However, up to our knowledge, the presentation of BA with both situs inversus and intestinal malrotation has only been reported three times [[14], [15], [16]].…”

Section: Discussionmentioning

confidence: 99%

Biliary atresia with an unusual abdominal orientation: A case report

Allarakia

Felemban

Khayyat

et al. 2019

International Journal of Surgery Case Reports

View full text Add to dashboard Cite

HighlightsBiliary atresia is a rare condition that causes jaundice in neonates.An association between biliary atresia and other developmental abnormalities has been reported.A presentation of biliary atresia with intestinal malrotation and situs ambiguous is extremely rare.The diagnosis and surgical management of such cases require meticulous evaluation.The use of post-operative steroids remains controversial.

show abstract

“…Other infrequently reported associations PSS are tracheo-esophageal fistula, renal anomalies, polydactyly, annular pancreas, choledochal cyst and intestinal atresias. 15 Association of polysplenia with PMDS is rare entity. This case was detected incidentally, while evaluating for acute ureteric colic.…”

Section: Discussionmentioning

confidence: 99%

Persistent Mullerian Duct Syndrome with Polysplenia and Short Pancreas: A Case Report

et al. 2019

View full text Add to dashboard Cite

Persistent Mullerian duct syndrome is a rare entity and usually presents with common symptoms of undescended testis and hernia. The syndrome is caused by an insufficient amount of Mullerian inhibiting substance or due to the insensitivity of the target organ to Mullerian inhibiting substance. Polysplenia is a rare congenital disease manifested by multiple small accessory spleens. The association of these two entities is rare and has not been reported in the literature. We reported a case of a 27 years old male presented with complains of right flank pain and nausea. Ultrasound showed right ureteric calculus with hydronephrosis and elongated soft tissue mass posterior to bladder. Contrast enhanced Computed Tomography showed soft tissue suggestive of infantile uterine structure with multiple splenculi and short pancreas. He was diagnosed as Persistent Mullerian duct syndrome with unilateral cryptorchidism, polysplenia and short pancreas, coincidentally detected while evaluating for ureteric colic.

show abstract

Biliary Atresia, Intestinal Malrotation, Partial Abdominal Heterotaxia, and Craniofacial Anomalies in a Newborn with Intrauterine Opiate Exposure

Cited by 5 publications

References 0 publications

When the right (Drug) should be left: Prenatal drug exposure and heterotaxy syndrome

When the right (Drug) should be left: Prenatal drug exposure and heterotaxy syndrome

Biliary atresia with an unusual abdominal orientation: A case report

Persistent Mullerian Duct Syndrome with Polysplenia and Short Pancreas: A Case Report

Contact Info

Product

Resources

About