Bilharziose et cancer : une association fortuite ou une relation de cause à effet

Gaye, Abdou Magib; Doh, K.; Thiam, Ibou; Bentefouet, Linda; Woto-Gaye, G.

doi:10.1016/j.bulcan.2016.07.002

Cited by 7 publications

(3 citation statements)

References 8 publications

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“…Bladder cancers were positive for histological evidence of schistosomal eggs in biopsies or surgical specimens, whilst 8 were histologically described as showing suggestive features for schistosomiasis NA [ 161 ] Bedwani R 1998 Egypt Case–control study Endemic area residents Eggs were searched in histological samples of patients with bladder cancer and in the urine of a control group to investigate the relationship between history of schistosomiasis and bladder cancer risk m/f Median [range]: 59 [21–78] Eggs in histological samples were found in 86/190 (45%) bladder cancer patients NA [ 162 ] Darré T 2015 Togo Retrospective study Endemic area residents Description of the histological specimens coming from bladder lesions observed during a 10-year time span Unspecified Unspecified Although most biopsies or surgical specimens were positive for eggs, 54 out of 192 (28.12%) bladder cancers were deemed to be caused by a chronic infection. The etiopathogenetic mechanism is not described for the other lesions NA [ 163 ] Gaye AM 2016 Senegal Retrospective study Endemic area residents Search of S. haematobium eggs in histological specimens of bladder cancers observed during a 5-year time span Unspecified Unspecified 31 of the 105 (29.5%) cases of bladder cancer were described as showing histological evidence of schistosomal eggs in biopsies or surgical specimens NA [ 164 ] Groeneveld AE 1996 Burkina Faso Retrospective study Endemic area residents Description of the histological specimens coming from bladder cancers observed during ...…”

Section: Resultsmentioning

confidence: 99%

Diagnosis and management of complicated urogenital schistosomiasis: a systematic review of the literature

et al. 2023

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Background Currently, there are no standardized guidelines for the diagnosis or management of the complications of urogenital schistosomiasis (UGS). This systematic review of the literature aims to investigate the state of the art in reference to diagnostic approaches and the clinical management of this condition. Methods A systematic review of literature published between January 1990 and January 2021 was conducted in the MEDLINE database, scoping for articles regarding diagnostic means or therapeutic options for the complications of UGS, namely obstructive uropathy, bladder cancer, abortion, ectopic pregnancy, infertility, kidney failure, urolithiasis and the need for invasive procedures. Relevant data were then extracted from the articles deemed eligible according to the inclusion criteria. Main results In total, 3052 articles were identified by the research query, of which 167 articles fulfilling inclusion criteria after title/abstract screening and full-text evaluation were included, 35% on both diagnostic and therapeutic aspects, and 51% on diagnosis and 14% on therapy. Ultrasound was the most frequently tool employed for the diagnosis of UGS complications showing a good performance. Concerning the management of hydronephrosis, the majority of available evidences came from community-based studies where universal treatment with praziquantel was used leading to decrease of prevalence of obstructive uropathy. Concerning studies on surgical procedures, laser endoureterotomy followed by stenting was mostly employed in adult patients leading to a crude cure rate of 60% (43 of 71 patients). In the case of severe hydronephrosis, surgery consisting of ureteral re-implantation showed excellent results with a crude cure rate of 98% (157 cured patients of 160 treated). Concerning bladder cancer, data on 93 patients with a clear diagnosis of UGS-related bladder were available reporting a variable and sometime combined approach based on disease stage. Available data on diagnosis and management of abortion, ectopic pregnancy, infertility, kidney failure, urolithiasis and the need for invasive procedures due to UGS are also presented. Conclusions The review produced a complete picture of the diagnostic and therapeutic options currently available for complicated UGS. These results can be useful both for guiding clinicians towards correct management and for tracing the direction of future research.

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Section: Resultsmentioning

confidence: 99%

Diagnosis and management of complicated urogenital schistosomiasis: a systematic review of the literature

et al. 2023

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“…Several cases of cervical schistosomiasis have been reported and some are associated with cancer. In Senegal, Abdou Magib Gaye et al [12] reported 6 cases, which represent 33.3% of cervical schistosomiasis and 0.2% of all cases of cervical cancer. Malagasy studies by Rajaonarison JJC et al [5] and Randrianasolo BS et al [13] concerning genital schistosomiasis, have not reported any association with cervical cancer.…”

Section: Discussionmentioning

confidence: 99%

“…Only persistent infections with high-risk HPV types will eventually result in progression towards invasive cervical cancer. Schistosomiasis may be a probable cofactor of uterine cervix cancer [12]. Kjetland et al [4] found that the development of high-grade intraepithelial neoplasia was significantly associated with cervical schistosomiasis that has progressed for at least 5 years [4] [8].…”

Section: Discussionmentioning

confidence: 99%