Bile duct necrosis after partial hepatectomy and transcatheter hepatic arterial embolization.

Gotoh, Mitsuru; Monden, Morito; Sakon, Masato; Kanai, Takanori; Umeshita, Koji; Endoh, W; Okamura, J; Wakasa, Kenichi; Sakurai, Michio; Marukawa, T

doi:10.2214/ajr.154.5.2108560

Cited by 7 publications

(3 citation statements)

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“…The most toxic combination appears to consist of chemotherapy, Lipiodol, and gelatin sponge. 31,33 Other factors that might exacerbate bile duct ischemia in patients treated with intraarterial chemotherapy include prior liver resection, 32,98 catheter-related HA dissection, high-dose chemotherapy, and large volumes of embolic agents.…”

Section: Outcome and Prognosismentioning

confidence: 99%

Ischemic Cholangiopathy

Deltenre¹,

Valla²

2008

Semin Liver Dis

109

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Bile ducts are supplied with blood exclusively via hepatic arteries. Obstruction of large arteries is rapidly compensated for by the opening of preexisting intrahepatic or transcapsular collateral arteries, which prevents ischemic damage. Ischemic bile duct injury may occur when small hepatic arteries or the peribiliary vascular plexus are injured, or when all possible arterial blood supplies are interrupted, as is the case in transplanted liver with hepatic artery thrombosis. Most causes of bile duct ischemia are iatrogenic. Systemic diseases involving small hepatic arteries may also be implicated. Depending on the extent and velocity of the arterial obstructive process, ischemic cholangiopathy may present as acute formation of biliary casts, bile duct necrosis, or chronic disease resembling primary sclerosing cholangitis. In many patients, correction of arterial obstruction is not possible. When biliary drainage or reconstruction is not possible or has failed, liver transplantation is the only means of providing potential cure.

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Section: Outcome and Prognosismentioning

confidence: 99%

Ischemic Cholangiopathy

Deltenre¹,

Valla²

2008

Semin Liver Dis

109

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“…The most toxic combination appears to consist of chemotherapy, lipiodol and gelatin sponge [66,68]. Other factors could exacerbate bile duct ischemia: prior liver resection [67,90]; catheter-related HA dissection; high dose chemotherapy and large volumes of embolic agents.…”

Section: Hepatic Arterial Infusion Of Toxic Agentsmentioning

confidence: 99%

Ischemic cholangiopathy

Deltenre

Valla

2006

Journal of Hepatology

123

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“…In this regard, we previously reported that extensive bile duct necrosis occurs easily when bile duct resection and hepatic artery occlusion are performed simultaneously. 10,11 Okajima et al reported that a subsequently detected metastatic liver tumor was treated with transcatheter arterial embolization (TAE) and weeks later intrahepatic abscesses developed in patients undergone pancreoduodenectomy. 12 Hasegawa et al reported a case of ischemic cholangitis that caused by TAE after hepatectomy for hepatocellular carcinoma with a resection of the extrahepatic bile duct.…”

Section: Discussionmentioning

confidence: 99%

Liver Abscess Formation After Microwave Coagulation Therapy Applied for Hepatic Metastases from Surgically Excised Bile Duct Cancer: Report of a Case

et al. 2002

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We report the case of a liver abscess associated with microwave coagulation therapy (MCT). A 67-year-old man underwent a pylorus-preserving pancreatoduodenectomy for bile duct cancer in August 1998. In June 1999, abdominal computed tomography (CT) showed three low-density areas in his liver. With a diagnosis of multiple metastatic liver tumors, we applied MCT to each liver tumor. The patient presented with fever after therapy. Abdominal CT showed a hepatic abscess, which was treated by percutaneous transhepatic abscess drainage under ultrasonography. A bacteriological examination of the pus material revealed the presence of Enterococcus faecalis and Candida albicans. Treatment resulted in a rapid resolution of symptoms. Our case indicated that care should be exercised in using MCT for the treatment of liver tumors in patients who have undergone reconstructive surgery of the biliary tract.

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Bile duct necrosis after partial hepatectomy and transcatheter hepatic arterial embolization.

Cited by 7 publications

References 0 publications

Ischemic Cholangiopathy

Ischemic Cholangiopathy

Ischemic cholangiopathy

Liver Abscess Formation After Microwave Coagulation Therapy Applied for Hepatic Metastases from Surgically Excised Bile Duct Cancer: Report of a Case

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