Abstract:Bile cell--free DNA: a game changer for management of biliary tract cancer?Recent years have witnessed the advent of molecular profiling in biliary tract cancer (BTC), and new techniques and technologies have led to the identification of a variety of molecular alterations. 1 Preliminary studies have suggested a high correspondence between mutational profile in BTC tissue and bile, and the detection of tumor-specific genetic aberrations with utilization of bile cell-free DNA (cfDNA) is under evaluation, althoug… Show more
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