Bile Acids and Bilirubin Role in Oxidative Stress and Inflammation in Cardiovascular Diseases
Angela Punzo,
Alessia Silla,
Federica Fogacci
et al.
Abstract:Bile acids (BAs) and bilirubin, primarily known for their role in lipid metabolism and as heme catabolite, respectively, have been found to have diverse effects on various physiological processes, including oxidative stress and inflammation. Indeed, accumulating evidence showed that the interplay between BAs and bilirubin in these processes involves intricate regulatory mechanisms mediated by specific receptors and signaling pathways under certain conditions and in specific contexts. Oxidative stress plays a s… Show more
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