Bildgebung bei Tumorprädispositionssyndromen

Glutig, Katja; Pfeil, Alexander; Renz, Diane M.

doi:10.1007/s00117-021-00861-z

Cited by 1 publication

(1 citation statement)

References 46 publications

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“…The Taskforce Oncology Guidelines of the European Society for Paediatric Radiology confirm their significance on a global scale [ 3 ]. WB-MRI is highly valuable in the diagnosis of oncological conditions such as Hodgkin’s and non-Hodgkin’s lymphomas [ 4 ], the diagnosis of distant disease in osteo-, Ewing and soft tissue sarcomas [ 5 ] and in Langerhans cell histiocytosis [ 6 ] and for the monitoring of tumour predisposition syndromes [ 7 ]. Additionally, WB-MRI is performed for radiation-free diagnosis in infancy and adolescence of non-oncological disorders such as chronic non-bacterial osteomyelitis and chronic recurrent multifocal osteomyelitis [ 8 , 9 ].…”

Section: Introductionmentioning

confidence: 99%

Whole-body diffusion magnetic resonance imaging with simultaneous multi-slice excitation in children and adolescents

et al. 2023

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Background Whole-body magnetic resonance imaging (WB-MRI) is an increasingly used guideline-based imaging modality for oncological and non-oncological pathologies during childhood and adolescence. While diffusion-weighted imaging (DWI), a part of WB-MRI, enhances image interpretation and improves sensitivity, it also requires the longest acquisition time during a typical WB-MRI scan protocol. Interleaved short tau inversion recovery (STIR) DWI with simultaneous multi-slice (SMS) acquisition is an effective way to speed up examinations. Objective In this study of children and adolescents, we compared the acquisition time, image quality, signal-to-noise ratio (SNR) and apparent diffusion coefficient (ADC) values of an interleaved STIR SMS-DWI sequence with a standard non-accelerated DWI sequence for WB-MRI. Materials and methods Twenty children and adolescents (mean age: 13.9 years) who received two WB-MRI scans at a maximum interval of 18 months, consisting of either standard DWI or SMS-DWI MRI, respectively, were included. For quantitative evaluation, the signal-to-noise ratio (SNR) was determined for b800 images and ADC maps of seven anatomical regions. Image quality evaluation was independently performed by two experienced paediatric radiologists using a 5-point Likert scale. The measurement time per slice stack, pause between measurements including shim and total measurement time of DWI for standard DWI and SMS-DWI were extracted directly from the scan data. Results When including the shim duration, the acquisition time for SMS-DWI was 43% faster than for standard DWI. Qualitatively, the scores of SMS-DWI were higher in six locations in the b800 images and four locations in the ADC maps. There was substantial agreement between both readers, with a Cohen’s kappa of 0.75. Quantitatively, the SNR in the b800 images and the ADC maps did not differ significantly from one another. Conclusion Whole body-MRI with SMS-DWI provided equivalent image quality and reduced the acquisition time almost by half compared to the standard WB-DWI protocol.

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