Bilateral versus unilateral thyroid eye disease

Kashkouli, Mohsen Bahmani; Kaghazkanani, Reza; Heidari, Iraj; Ketabi, Nooshin; Jam, Sara; Azarnia, Shahrzad; Pakdel, Farzad

doi:10.4103/0301-4738.83612

Cited by 31 publications

(41 citation statements)

References 11 publications

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“…We recently showed that there is no significant difference between unilateral vs bilateral TED regarding the demographics, type of thyroid disease, associated findings, and severity and activity of TED. 15 Our data indicated that patients with U-TED belonged to the same population as those with bilateral eye disease. 15 Similar to Eckstein et al, 3 we found no significant difference with regard to the age, gender, and smoking habit between Hr-TED vs Ho-TED (Table 1).…”

Section: Resultsmentioning

confidence: 51%

“…15 Our data indicated that patients with U-TED belonged to the same population as those with bilateral eye disease. 15 Similar to Eckstein et al, 3 we found no significant difference with regard to the age, gender, and smoking habit between Hr-TED vs Ho-TED (Table 1). Manji et al 28 have also stated that the presence of ophthalmopathy in both hyperthyroid and hypothyroid patients (Hashimoto thyroiditis) was not independently associated with gender.…”

Section: Resultsmentioning

confidence: 51%

“…2,15 The aim of this study was to compare demographics and clinical manifestations, especially severity and activity scores, of patients with Hr-TED with Ho-TED. To the best of our knowledge, there was only one recent study 2 that systematically compared the clinical characteristics of Hr-TED with Ho-TED.…”

Section: Introductionmentioning

confidence: 99%

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Hyperthyroid vs hypothyroid eye disease: the same severity and activity

Kashkouli

Pakdel

Kiavash

et al. 2011

Eye

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Purpose To compare demographics, severity, and activity of thyroid eye disease (TED) in patients with hyperthyroidism (Hr-TED) vs primary hypothyroidism (Ho-TED). Patients and MethodsIn a cross-sectional study, demographics, complete eye examination, severity score (NOSPECS, total hundred eye score), clinical activity score, and Rundle grading were recorded for patients with TED and different thyroid disorders referred from an endocrinology clinic from 2003 to 2006. Results TED was clinically found in 303 patients (303/851, 35.6%). The majority of them (280/303, 92.4%) had Graves' hyperthyroidism and 23 (23/303, 7.5%) had primary hypothyroidism. Mean age, gender, mean severity score, mean activity score, Rundle grade, unilateral presentation of TED, smoking habit, mean duration of eye disease, and mean interval time of thyroid to TED were not significantly different between the two groups (0.06oPo0.9). Mean duration of thyroid disease was significantly (P ¼ 0.02) longer in the Hr-TED group (49.6 months) than in the Ho-TED group (22.7 months). Most of the patients in both groups (63.2% of Hr-TED and 73.9% of Ho-TED) developed the eye disease within 18 months before or after the thyroid disease. Conclusion The same demographics, clinical characteristics, and severity and activity scores for Hr-TED and Ho-TED imply that both groups present the same category of eye disease.

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Section: Resultsmentioning

confidence: 51%

Section: Resultsmentioning

confidence: 51%

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Hyperthyroid vs hypothyroid eye disease: the same severity and activity

Kashkouli

Pakdel

Kiavash

et al. 2011

Eye

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“…We have defined thyroid eye disease as presence of any one sign of thyroid eye disease (NOSPECS) while other studies have taken at least two signs [18]. In a study done in India by Mohsen Bahmani Kashkouli et al [19], the prevalence was 35.6%.…”

Section: Discussionmentioning

confidence: 99%

Ocular Manifestations in Thyroid Eye Disorder: A Cross-Sectional Study from Nepal

Sabita¹,

Ajit²,

Narayan³

et al. 2016

IJCM

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Background: Thyroid eye disease represents an organ-specific autoimmune process that is usually associated with thyroid disease. Graves' disease is the most common thyroid abnormality associated with thyroid eye disease. Aim: This study was conducted for the profile of ocular manifestation in Thyroid Eye Disease (TED). Methodology: A cross-sectional study of 117 cases of thyroid dysfunction was carried out at BP Koirala Institute of Health System, out of which 84 (71.79%) cases had ocular manifestation. They were evaluated and analyzed in detail and the characteristics documented included patient's demography, ocular and systemic history and as well as ocular examination and some of the systemic and laboratory findings. Results: In this study, mean age of presentation of TED was 39.7 years. 59 patients were female and 25 were male. The maximum patients of both sexes were in the fourth decade of their lives. The common lid signs were lid retraction and lid lag. Proptosis was seen in 33.3% of cases out of which 68% had bilateral proptosis. Corneal ulcer was seen in 7.1% and optic neuropathy in 1.2% of cases. In 27.3% of cases there was elevation of IOP. Dry eye was seen in 61.9% of cases and POAG seen in 8.3% of cases. In the study population 75% were hyperthyroiditic, 16.7% were hypothyroiditic and 8.3% were in euthyroid state. Conclusion: Female was more commonly affected. The maximum number of patients of both sexes was in the fourth decade of their lives. Hyperthyroidism patient had greater chance of ocular manifestation.

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“…Thyroid ophthalmopathy is usually associated with Graves’ disease; however, in 6.2% of patients with thyroid eye disease it can be associated with hypothyroidism 1. A 54-year-old woman from Tamil Nadu presented to our outpatient department with sudden onset of binocular diplopia for the past 5 months.…”

Section: Descriptionmentioning

confidence: 99%