Bilateral versus unilateral hearing aids for bilateral hearing impairment in adults

Schilder, Anne G. M.; Chong, Lee Yee; Ftouh, Saoussen; Burton, Martin J

doi:10.1002/14651858.cd012665.pub2

Cited by 29 publications

(27 citation statements)

References 22 publications

(7 reference statements)

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“…If the metaanalysis is not feasible due to considerable clinical and methodological heterogeneity, a qualitative summary of the results will be conducted. 28 Subgroup analysis and investigation of heterogeneity Subgroup analysis will be performed to detect possible causes of heterogeneity in the previous analysis if necessary. It will be conducted according to variations in the characteristics of the participants, moxibustion treatments and controls.…”

Section: Data Synthesismentioning

confidence: 99%

Effects of moxibustion on symptoms of mild cognitive impairment: protocol of a systematic review and meta-analysis

Zhang

Wang

et al. 2020

BMJ Open

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IntroductionMild cognitive impairment (MCI) is considered the intermediate phase between normal age-related cognitive decline and dementia. Moxibustion has gained increased popularity for the management of MCI in China.This study aimed to evaluate the effects and safety of moxibustion on symptoms of MCI.Methods and analysisFour English databases and six Chinese databases will be searched from their inception to October 2019: Embase, MEDLINE, Cochrane Central Register of Controlled Trials, Allied and Complementary Medicine Database, China National Knowledge Infrastructure, Chongqing VIP Chinese Science and Technology Periodical Database, Wanfang Database, SinoMed, China Doctoral Dissertations Full-text Database and the China Master’s Theses Full-text Database. Only clinical randomised controlled trials and the first period in randomised cross-over trial related to moxibustion for MCI will be included. The primary outcomes include the improvement of cognitive function, as measured by validated assessment tools. The secondary outcomes include changes in the activity of daily living scale, effective rate and the incidences of adverse events. The selection of studies, data extraction and risk of bias assessment will be carried out by two independent reviewers. Review Manager V.5.3 software will be used for statistical analyses. Heterogeneity test, data synthesis and subgroup analysis will be performed if necessary. The risk of bias of included studies will be assessed by theCochrane Handbookrisk of bias tool. Evidence quality will be evaluated using the Grading of Recommendations Assessment, Development and Evaluation system.Ethics and disseminationEthics approval is not required as no private information from individuals are collected. The results will be published in a peer-reviewed journal or disseminated in relevant conferences.Trial registration numberCRD42018112657.

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Section: Data Synthesismentioning

confidence: 99%

Effects of moxibustion on symptoms of mild cognitive impairment: protocol of a systematic review and meta-analysis

Zhang

Wang

et al. 2020

BMJ Open

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“…However, when P<0.1 or I 2 >50%, the random-effect model will be used to provide a more conservative estimate of effect. 35 …”

Section: Methodsmentioning

confidence: 99%

Acupuncture for constipation in patients with stroke: protocol of a systematic review and meta-analysis

Zhai¹,

Mu²,

Si³

et al. 2018

BMJ Open

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IntroductionConstipation is one of the most common complications in patients with stroke. Acupuncture has gained increased popularity for the management of constipation. However, there is a lack of supportive evidence on the efficacy of acupuncture for poststroke constipation. This systematic review aims to collect and critically appraise all the available evidence about the efficacy and safety of the acupuncture for constipation in poststroke patients.Methods and analysisA comprehensive search of Pubmed, Embase, Cochrane Central Register of Controlled Trials, Web of Science, four Chinese databases (National Knowledge Infrastructure (CNKI), Chinese Biomedical Literatures database (CBM), Wanfang Digital Periodicals (WANFANG) and Chinese Science and Technology Periodicals (VIP) database), one Japanese medical database (National Institute of Informatics, CiNii) and one Korean medical database (Oriental Medicine Advanced Searching Integrated System, OASIS) will be conducted to identify randomised controlled trials of acupuncture for constipation in poststroke patients. There is no restriction on language or publication status. The primary outcome measure will be frequency of bowel movement. The risk of bias will be assessed using the approach recommended by Cochrane Handbook for Systematic Reviews of Interventions. We will conduct the meta-analysis to synthesise the evidence for each outcome, if possible. The heterogeneity will be statistically assessed using a χ2 test and I2 statistic. This protocol is developed following the guideline of Preferred Reporting Items for Systematic Reviews and Meta-analyses Protocols 2015.Ethics and disseminationThe ethical approval is not required because no primary data are collected. The findings will be presented at scientific conferences or a peer-reviewed scientific journal.PROSPERO registration number CRD42017076880.

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“…Hearing aids and cochlear implants should be regarded as symptomatic treatments that are able to restore functionality (i.e., communication) and quality of life to a certain level. Bilateral cochlear implantation has been reported to restore binaural hearing to a certain level and improve speech comprehension, while reducing tinnitus burden and psychological comorbidities (8)(9)(10). However, in most health services, adult cochlear implantation is only reimbursed in a single ear because of its significant cost (10,11).…”

Section: Rehabilitation Of Hearing Lossmentioning

confidence: 99%

Making the Case for Research on Disease-Modifying Treatments to Tackle Post-lingual Progressive Sensorineural Hearing Loss

Rompaey

2020

Front. Neurol.

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Hearing loss not only has a significant impact on the quality of life of patients and society, but its correlation with cognitive decline in an aging population will also increase the risk of incident dementia. While current management of hearing loss is focused on hearing rehabilitation (and essentially symptomatic), patients are suffering from the burden of progressive hearing loss before hearing aids or cochlear implants are fitted. Although these devices have a significant effect on speech understanding, they do not always lead to normal speech understanding, especially in noisy environments. A significant number of patients suffer from autosomal dominantly inherited disorders that can produce progressive sensorineural hearing loss. This includes DFNA9, a disorder caused by pathologic variants in the COCH gene that leads to post-lingual profound sensorineural hearing loss and bilateral vestibulopathy. Carriers of a pathogenic variant leading to DFNA9 can be diagnosed at the pre-symptomatic or early symptomatic stage which creates a window of opportunity for treatment. Preventing hearing loss from occurring or stabilizing progression would provide the opportunity to avoid hearing aids or cochlear implants and would be able to reduce the increased incidence of dementia. While innovative therapies for restoration of hearing have been studied for restoration of hearing in case of severe-to-profound sensorineural hearing loss and congenital hearing loss, further research is needed to study how we can modify disease progression in late-onset autosomal dominant hereditary sensorineural hearing loss. Recently, gene editing strategies have been explored in autosomal dominant disorders to disrupt dominant mutations selectively without affecting wild-type alleles.

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Bilateral versus unilateral hearing aids for bilateral hearing impairment in adults

Cited by 29 publications

References 22 publications

Effects of moxibustion on symptoms of mild cognitive impairment: protocol of a systematic review and meta-analysis

Effects of moxibustion on symptoms of mild cognitive impairment: protocol of a systematic review and meta-analysis

Acupuncture for constipation in patients with stroke: protocol of a systematic review and meta-analysis

Making the Case for Research on Disease-Modifying Treatments to Tackle Post-lingual Progressive Sensorineural Hearing Loss

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