Bilateral tubal ectopic pregnancy after in vitro fertilization and embryo transfer

Chang, Jong-Chou; Lin, Yixiao; Sun, Ta-Teh

doi:10.1007/bf01139788

Cited by 3 publications

(2 citation statements)

References 10 publications

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“…On the other hand, the incidence of heterotopic pregnancy in spontaneous conception pregnancies, which was once considered very rare (1 in 30 000 pregnancies), now complicates 1 in 4000 to 1 in 7000 pregnancies (Ben-Rafael et al, 1985). This increase is due primarily to the use of exogenous pituitary gonadotrophins (Dietz et al, 1993) and the increasing use of IVF (Chang et al, 1991;Rizk et al, 1991). The incidence of heterotopic pregnancy subsequent to IVF treatment ranges from 1 to 3% of all clinical pregnancies (Yovich et al, 1985;Berman et al, 1986;Dor et al, 1991;Dimitry and Reid, 1993;Tal et al, 1996).…”

Section: Incidencementioning

confidence: 99%

Extra-uterine pregnancy following assisted conception treatment

Abusheikha

Salha²,

Brinsden³

2000

Human Reproduction Update

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Ectopic pregnancy may be the only life-threatening disease in which prevalence has increased as mortality has declined. The most prominent theory to explain this phenomenon involves increased sensitivity of serum beta-human chorionic gonadotrophin (HCG) immunoassay and improved quality of transvaginal ultrasound, combined with a heightened awareness and increased suspicion of the condition among clinicians which has allowed early detection of ectopic pregnancy. Laparotomy, once the standard treatment of ectopic pregnancy, has been replaced almost entirely by operative laparoscopy. This is associated with a shorter hospital stay, fewer post-operative analgesic requirements, reduced costs and lower risk of adhesion formation. Laparotomy, however, remains necessary in cases with haemodynamic instability and with exceptional locations, e.g. cervical, abdominal and interstitial implantation. In selected cases, non-surgical management has also obtained high success rates. Among medical therapies, the most common is systemic or local administration of methotrexate. The other option is expectant management involving follow-up using serial serum HCG measurements and ultrasound scans. Thus, life-threatening ectopic pregnancy is now evolving into a medical disease, with the possibility of lower-cost treatment, faster recovery and higher subsequent fertility. In this review we assess the risk of extra-uterine implantation after assisted conception treatment, the accuracy of various diagnostic tools and focus on the efficacy, safety and the fertility outcomes of surgical and nonsurgical management of ectopic pregnancy.

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Section: Incidencementioning

confidence: 99%

Extra-uterine pregnancy following assisted conception treatment

Abusheikha

Salha²,

Brinsden³

2000

Human Reproduction Update

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“…BTP has been reported in women with spontaneous menstrual cycles,9-11 following tubal surgery,12-14 in ovarian hyperstimulation cycles,15 and in such procedures as gamete intrafallopian transfer (GIFT) and in vitro fertilization and embryo transfer (IVF-ET). [16][17][18][19][20][21][22] In IFV cycles, the main extrauterine gestation sites are the salpinges, with a frequency of 74.8% of the total number of EP. At the ovarian level, the frequency is 5.9%, heterotopic pregnancies 14.8%, and BTP 4.4%.5 The first case of BTP treated conservatively by laparoscopy was reported by Molina Because of the rarity of BTP, preoperative diagnosis is difficult.…”

Section: Introductionmentioning

confidence: 99%

Conservative Laparoscopic Treatment of Bilateral Ectopic Pregnancy: Two Case Reports and Review of the Literature

Bustos-López¹,

Rojas-Poceros²,

Barron-Vallejo³

et al. 1998

Journal of Gynecologic Surgery

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Bilateral tubal pregnancy is a rare entity, reported as 1 in 125 to 1 in 1580 of the total number of extrauterine pregnancies. Two clinical cases of bilateral tubal pregnancy, treated conservatively by laparoscopy, are presented. The first patient had a history of primary infertility due to anovulation and received menotropins for ovulation induction. She was treated by linear salpingostomy in one of the tubes and distal expression (milking) in the other because of its infundibular-ostial location. The second case is a report of a woman who had multiple pelvic surgeries and had an ectopic pregnancy from a spontaneous pregnancy. In this later case, bilateral linear salpingostomy was performed. In both women, chorionic villi were demonstrated by histopathology. These cases are a model of nature indicating the usefulness of various currently used diagnostic and therapeutic methods in the management of ectopic pregnancy. (

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