Bilateral Temporal Arachnoid Cysts in Neurofibromatosis

Abstract

The occurrence of bilateral temporal arachnoid cysts has been considered as a rare event. Unilateral arachnoid pouches have been reported in a few instances associated with neurofibromatosis. The authors describe a 5-year-old girl with bilateral temporal arachnoid cysts who presented obvious stigmata of van Recklinghausen's disease. To the best of our knowledge, this is the first time that this association has been described in the literature.

Bilateral Temporal Arachnoid Cysts Associated With Tuberous Sclerosis Complex

“…However, some patients with neurofibromatosis were reported to have arachnoid cysts, and 1 patient with neurofibromatosis had bilateral temporal arachnoid cysts. 19 Based on these observations, which are compatible with cortical developmental abnormalities, we believe that genetic factors are responsible for this association. Knowledge of this patient's tuberous sclerosis complex gene mutation will not help to find the mechanism by which he developed the arachnoid cysts.…”

Outcome of 12 antenatally diagnosed fetal arachnoid cysts: Case series and review of the literature

“…Chromosomal abnormality Other features Hogge et al 10 Partial trisomy 9q and partial monosomy Xq Prominent Nose, micrognatia, overlapping fingers, thin wall cyst compressing the right cerebral hemisphere Souter et al 19 Monosomy 14q Tetralogy of Fallot, IUGR, midline intracranial arachnoid cyst Pilu et al 12 Trisomy 18 Small arachnoid cyst in the ambient cistern, double outlet right ventricle, clenched hands Chen et al 24 Trisomy 18 Microcephaly, hypogenesis of cerebellar vermis, syndactyly, VSD, rocker-bottom feet Stein et al 25 Trisomy 20 mosaicism Arachnoid cyst of the basal cistern Bannister et al 27 Pallister-Hall, Aicardia Napolitano et al 34 Seckle syndrome Microcephaly, hypotelorism, beaked nose, micrognathia Kau et al 43 Chudley-Mc Cullough syndrome Martinez-Lage et al 44 Neurofibromatosis type 1 e u r o p e a n j o u r n a l o f p a e d i a t r i c n e u r o l o g y 1 9 ( 2 0 1 5 ) 1 1 4 e1 2 1…”

Type 1 neurofibromatosis associated with asymptomatic cystic malformations of central nervous system (CNS)

“…Among the intracranial space‐occupying lesions, the reported incidence of arachnoid cyst forms only 1%, and they are nearly always sporadic and single, although cysts are very rarely bilateral 10 . A few patients with neurofibromatosis were revealed to have arachnoid cysts and only one case with bilateral temporal arachnoid cysts, as in our second patient, was reported 5,9 . Also one with tuberous sclerosis complex was found to have the bilateral temporal arachnoid cysts 10 .…”

“…Arachnoid cysts are nontumoral intra‐arachnoid fluid collections that may appear throughout the cerebrospinal axis 5,9 . Among the intracranial space‐occupying lesions, the reported incidence of arachnoid cyst forms only 1%, and they are nearly always sporadic and single, although cysts are very rarely bilateral 10 .…”