Bilateral Talc Maculopathy and Fibrovascular Proliferation in a Drug Abuser

Ruys, J; Smet, Marc D. de; Sompel, W Van De

doi:10.1097/icb.0b013e31819bfa57

Cited by 7 publications

(5 citation statements)

References 2 publications

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“…Длительная эмболизация частицами талька вызывает недостаточную перфузию и, как следствие, ишемию сетчатки и активацию процессов неоваскуляризации [2,[7][8][9][10].…”

Section: Discussionunclassified

Talc retinopathy as a result of long-term intravenous drug abuse

Matyaeva,

Slastina

2023

Aspirantskiy Vestnik Povolzhiya

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Narcotic substances have a pronounced toxic effect on the entire body and can lead to disability. Despite ongoing efforts to combat drug addiction, in today's society, many drugs are available for potential use. Their destructive action leads to numerous adverse ocular and systemic manifestations. The most frequently, the drug-users are people of working age, in whom visual impairment leads to restrictions on labor and social activities. The article considers a clinical case of talcum retinopathy, which developed as a result of long-term abuse of intravenous drugs; the ophthalmic manifestations and a possible treatment option are described.

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Section: Discussionunclassified

Talc retinopathy as a result of long-term intravenous drug abuse

Matyaeva,

Slastina

2023

Aspirantskiy Vestnik Povolzhiya

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“…5 Although talc retinopathy usually results in minimal changes in vision, occlusive events can accumulate and eventually lead to more extensive damage. Macular or peripheral ischemia can occur, 7 leading to proliferative ischemic retinopathy. 1 Emboli may also accumulate into larger refractile particles that eventually occlude the vessel distally, as described by Zoumalan and Marmor.…”

Section: Discussionmentioning

confidence: 99%

Ophthalmic Artery Occlusion From Injection of Heroin Into the Forehead

Ploysangam

Koreishi

Lema

2019

Journal of VitreoRetinal Diseases

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Purpose: To report a case of ophthalmic artery occlusion after injection of heroin into the forehead. Methods: Retrospective case report. Results: A 27-year-old patient with a history of intravenous heroin abuse presented with a left ophthalmic artery occlusion after attempting to inject heroin into a vein in her forehead. Exam was significant for diffuse retinal edema, disc edema, disc hemorrhage, and diffuse retinal hemorrhages. Findings were also noted in the widefield image, optical coherence tomography, and optical coherence tomography angiography of the retina. Conclusions: This patient suffered from a severe form of talc retinopathy resulting in an ophthalmic artery occlusion after injecting heroin into her forehead. To our knowledge, this is the first instance of combined ophthalmic artery occlusion and talc retinopathy resulting from intentional injection into a superficial facial vein.

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“…If substance abuse is stopped, retinopathy can stabilize, or it may be nonprogressive in nature. 353,354 Laser photocoagulation or pars plana vitrectomy may be necessary to treat neovascularization and vitreous hemorrhage.…”

Section: Managementmentioning

confidence: 99%

“…After talc retinopathy diagnosis, it is important to educate patients regarding the cause of retinopathy. If substance abuse is stopped, retinopathy can stabilize, or it may be nonprogressive in nature 353,354. Laser photocoagulation or pars plana vitrectomy may be necessary to treat neovascularization and vitreous hemorrhage.…”

Section: Vascular Relatedmentioning

confidence: 99%

The Impact of Systemic Medications on Retinal Function

Somisetty

Santina

Sarraf

et al. 2023

Asia-Pacific Journal of Ophthalmology

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This study will provide a thorough review of systemic (and select intravitreal) medications, along with illicit drugs that are capable of causing various patterns of retinal toxicity. The diagnosis is established by taking a thorough medication and drug history, and then by pattern recognition of the clinical retinal changes and multimodal imaging features. Examples of all of these types of toxicity will be thoroughly reviewed, including agents that cause retinal pigment epithelial disruption (hydroxychloroquine, thioridazine, pentosan polysulfate sodium, dideoxyinosine), retinal vascular occlusion (quinine, oral contraceptives), cystoid macular edema/retinal edema (nicotinic acid, sulfa-containing medications, taxels, glitazones), crystalline deposition (tamoxifen, canthaxanthin, methoxyflurane), uveitis, miscellaneous, and subjective visual symptoms (digoxin, sildenafil). The impact of newer chemotherapeutics and immunotherapeutics (tyrosine kinase inhibitor, mitogen-activated protein kinase kinase, checkpoint, anaplastic lymphoma kinase, extracellular signal-regulated kinase inhibitors, and others), will also be thoroughly reviewed. The mechanism of action will be explored in detail when known. When applicable, preventive measures will be discussed, and treatment will be reviewed. Illicit drugs (cannabinoids, cocaine, heroin, methamphetamine, alkyl nitrite), will also be reviewed in terms of the potential impact on retinal function.

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Bilateral Talc Maculopathy and Fibrovascular Proliferation in a Drug Abuser

Abstract: Intravenous drug abuse can cause retinopathy. This article is about a young cocaine abuser with bilateral crystalline maculopathy and extensive peripheral retinal neovascularization.

Cited by 7 publications

References 2 publications

Talc retinopathy as a result of long-term intravenous drug abuse

Talc retinopathy as a result of long-term intravenous drug abuse

Ophthalmic Artery Occlusion From Injection of Heroin Into the Forehead

The Impact of Systemic Medications on Retinal Function

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