Bilateral pseudoangiomatous stromal hyperplasia in childhood gigantomastia: A challenge in reconstruction and management

Bilateral multicenter pseudohemangiomatous interstitial hyperplasia of the breast: a case report

“…However, total mastectomy can be considered for extensive lesions that have spread throughout the breast [ 21 ]. There are few reports on one-stage prosthetic reconstruction performed after resection [ 4 , 6 ]. Here, we discuss a 43-year-old female patient with bilateral multicenter PASH.…”

“…The clinical manifestations of PASH include a tumor-forming lesion (tumorous PASH) or gigantomastia (diffuse PASH). Most of the cases addressed in the past were unilateral tumour PASH, and very few cases of bilateral PASH have been recorded [ 5 , 6 ]. In this article, we describe a rare case of bilateral multicenter tumorous PASH in a patient that underwent total mastectomy and one-stage implant-based breast reconstruction.…”

A rare case of gigantomastia caused by pseudoangiomatous stromal hyperplasia

“…The differential diagnosis of gigantomastia includes phyllodes tumor, giant fibroadenoma, fibrocystic disease, sarcoma and PASH disease [3,4].…”

Hiperplasia estromal pseudoangiomatosa de la mama

“…La principal hormona que produce estimulación de los miofibroblastos es la progesterona (5,6). Esto es apoyado por el hecho de que la mayoría de los casos ocurren en premenopáusicas (7). Además, más de la mitad de los casos en menopáusicas tenían antecedentes de uso de tratamiento con terapia hormonal, lo cual apoya esta teoría (5,6).…”