Bilateral Pheochromocytomas: Incidental Finding in a Trauma Patient

Raby, Linda

doi:10.1016/j.jen.2011.04.018

Cited by 4 publications

(4 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…At physical examination, there was evidence of many brown color lesions mainly located at the trunk (more than six) measuring 16 mm and several neurofibromas on the trunk and limbs (Figure 1). These findings were the pathognomonic can be bilateral (5)(6) . Nowadays, a genetic test is important in pheochromocytoma diagnosis, as it is most often associated with a hereditary cause, especially in the bilateral form and can help in the prognostic score (7) .…”

Section: Case Reportmentioning

confidence: 67%

See 1 more Smart Citation

Cafe-au-lait spots with resistant hypertension are an indicator of pheochromocytoma: a rare case report

Amri,

Tamir,

Drighil

et al. 2024

Arch Peru Cardiol Cir Cardiovasc

View full text Add to dashboard Cite

This case report is one of the rare cases of bilateral pheochromocytoma associated with neurofibromatosis type 1. The interest lies in the clinical form in which the diagnosis was revealed. We report the case of a 38-year-old woman admitted for severe hypertension resistant to triple therapy. Clinical examination revealed Cafe-au-lait spots, which are pigmented birthmarks that appear as patches on the skin with a light to dark brown colour. More than six spots are present in an estimated 95% of people diagnosed with neurofibromatosis type 1 (NF1). Abdominal computed tomography (CT) showed bilateral adrenal tumor involvement. The diagnosis of pheochromocytoma was made by measuring urinary Vanillylmandelic acid (VMA). The evolution was favorable after the excision of the tumor, with normalization of blood pressure. In conclusion: resistant hypertension with café au lait spots may indicate pheochromocytoma, especially bilateral, suggesting an underlying genetic condition like NF1, warranting systematic screening.

show abstract

Section: Case Reportmentioning

confidence: 67%

“…It is most often sporadic and unilateral. However,10% of pheochromocytoma cases can be bilateral 5 - 6 . Nowadays, a genetic test is important in pheochromocytoma diagnosis, as it is most often associated with a hereditary cause, especially in the bilateral form and can help in the prognostic score 7 .…”

Section: Discussionmentioning

confidence: 99%

Cafe-au-lait spots with resistant hypertension are an indicator of pheochromocytoma: a rare case report

Amri,

Tamir,

Drighil

et al. 2024

Arch Peru Cardiol Cir Cardiovasc

View full text Add to dashboard Cite

show abstract

“…Pheochromocytoma is most often sporadic and unilateral. However, in 10% of cases it can be bilateral [1][2][3][4]. In these patients, an underlying genetic disorder can be diagnosed in 80% of cases [2].…”

Section: Discussionmentioning

confidence: 99%

Bilateral pheochromocytoma: A case report

lafqih¹,

Aden²,

Rafi³

et al. 2023

World J. Adv. Res. Rev.

View full text Add to dashboard Cite

Pheochromocytoma is a rare tumor developed at the expense of chromaffin cells, the adrenal involvement is most often unilateral. But, in 10% of cases, a bilateral localization is observed. We report the case of a 62-year-old patient, without personal or family pathological history, was hospitalized for exploration of recurrent pain in the right hypochondrium. On examination, the patient reported headaches, palpitations and sweating, on biological examination, urinary methoxylates were elevated, adrenal CT showed a large tissue mass, with fine calcifications and central necrosis, measuring 12*12*8.2cm with a washout <50%, the MEN 1 test was negative, the genetic study was not available, the diagnosis of sporadic right pheochromocytoma was the most likely, The patient underwent a right surrenalectomy with anatopathological examination in favor of pheochromocytoma, in the framework of follow-up a MIBG scan was done at 1 year post-op, it showed the presence of a focus of abnormal and isolated capture opposite the left arm of the left adrenal measuring 10.8*8.3 mm, in favor of a pheochromocytoma, the patient was operated: left adrenalectomy and the anatomopathological examination was in favor of pheochromocytoma. In these patients with bilateral pheochromocytoma, an underlying genetic disorder can be diagnosed in 80% of cases. It is most often a multiple endocrine neoplasia type 2, apart from the genetic aspect of the disease, the discovery of bilateral involvement requires confirmation of the secretory or functional character of the two adrenal masses in view of the possibility of the association of a pheochromocytoma and an incidentaloma of another nature.

show abstract

“…Le phéochromocytome est le plus souvent sporadique et unilatéral. Néanmoins, dans 10% des cas, il peut être bilatéral [ 1 , 4 ]. Chez ces patients, une affection génétique sous jacente peut être diagnostiquée dans 80% des cas [ 2 ].…”

Section: Discussionunclassified

Le phéochromocytome surrénalien bilatéral: à propos d'un cas

Chérif¹,

Lamia²,

Samira³

et al. 2013

Pan Afr Med J

View full text Add to dashboard Cite

Les phéochromocytomes de localisation bilatérale sont rares. Ils s'intègrent le plus souvent dans le cadre d'une maladie familiale. Néanmoins des formes bilatérales sporadiques peuvent être observées. Ainsi, chez tout patient présentant des masses surrénaliennes bilatérales, un phéochromocytome bilatéral doit être suspecté et son caractère familial ou sporadique doit être déterminé devant le risque de récidive tumorale. A ce propos, nous rapportons l'observation d'une patiente âgée de 22 ans qui a été hospitalisée pour exploration d'une hypertension artérielle de découverte récente. L'association à des céphalées, sueurs et palpitations a orienté vers le diagnostic de phéochromocytome. Les taux urinaires des dérivés méthoxylés étaient très élevés. L’échographie et l'IRM abdominales ont noté la présence de deux masses surrénaliennes bilatérales. La scintigraphie au MIBG a montré une hyperfixation au niveau des deux surrénales, sans autres localisations. L'enquête à la recherche d'une néoplasie endocrinienne multiple ou d'une phacomatose était négative. Le traitement a consisté en une surrénalectomie bilatérale par voie cœlioscopique. L’évolution sous traitement substitutif par hydrocortisone était favorable avec une normalisation des chiffres tensionnels.

show abstract

Bilateral Pheochromocytomas: Incidental Finding in a Trauma Patient

Cited by 4 publications

References 1 publication

Cafe-au-lait spots with resistant hypertension are an indicator of pheochromocytoma: a rare case report

Cafe-au-lait spots with resistant hypertension are an indicator of pheochromocytoma: a rare case report

Bilateral pheochromocytoma: A case report

Le phéochromocytome surrénalien bilatéral: à propos d'un cas

Contact Info

Product

Resources

About