Bilateral optic disc oedema as the initial manifestation of leukaemic relapse

Isolated central nervous system primary acute monoblastic leukemia presenting as papilledema

“…Although CNS is a potential site for extramedullary disease, no reports of CNS disease without marrow involvement in primary leukemia were found in the literature. While there are case reports of CNS disease presenting as increased intracranial pressure, all occurred in relapse, not in primary disease . This case report emphasizes the need for systematic radiologic and laboratory review of CSF pleocytosis without a proven infectious etiology.…”

“…While there are case reports of CNS disease presenting as increased intracranial pressure, all occurred in relapse, not in primary disease. [1][2][3][4] This case report emphasizes the need for systematic radiologic and laboratory review of CSF pleocytosis without a proven infectious etiology.…”